A highly multiplexed broad pathogen detection assay for infectious disease diagnostics.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Jeffrey W Koehler, Christina E Douglas, Timothy D Minogue
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2018
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Rapid Point
• Online Access: https://doi.org/10.1371/journal.pntd.0006889; https://doaj.org/article/331216e300594f86a990c0aea6f827ad

Rapid pathogen identification during an acute febrile illness is a critical first step for providing appropriate clinical care and patient isolation. Primary screening using sensitive and specific assays, such as real-time PCR and ELISAs, can rapidly test for known circulating infectious diseases. I...