A lung image reconstruction from computed radiography images as a tool to tuberculosis treatment control
Abstract Background: Background: Tuberculosis (TB) is an infectious lung disease with high worldwide incidence that severely compromises the quality of life in affected individuals. Clinical tests are currently employed to monitor pulmonary status and treatment progression. The present study aimed t...
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ftdoajarticles:oai:doaj.org/article:32be3e333b984431909015b8f955dd23 2023-05-15T15:15:59+02:00 A lung image reconstruction from computed radiography images as a tool to tuberculosis treatment control Marcela de Oliveira Sergio Barbosa Duarte Guilherme Giacomini Paulo Câmara Marques Pereira Lenice do Rosário de Souza José Ricardo de Arruda Miranda Diana Rodrigues de Pina 2019-02-01T00:00:00Z https://doi.org/10.1590/1678-9199-jvatitd-1449-18 https://doaj.org/article/32be3e333b984431909015b8f955dd23 EN eng SciELO http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100302&lng=en&tlng=en https://doaj.org/toc/1678-9199 1678-9199 doi:10.1590/1678-9199-jvatitd-1449-18 https://doaj.org/article/32be3e333b984431909015b8f955dd23 Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 25, Iss 0 (2019) Tuberculosis Quantification Lung involvement Serum tests Pulmonary function tests Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 article 2019 ftdoajarticles https://doi.org/10.1590/1678-9199-jvatitd-1449-18 2022-12-31T00:14:19Z Abstract Background: Background: Tuberculosis (TB) is an infectious lung disease with high worldwide incidence that severely compromises the quality of life in affected individuals. Clinical tests are currently employed to monitor pulmonary status and treatment progression. The present study aimed to apply a three-dimensional (3D) reconstruction method based on chest radiography to quantify lung-involvement volume of TB acute-phase patients before and after treatment. In addition, these results were compared with indices from conventional clinical exams to show the coincidence level. Methods: A 3D lung reconstruction method using patient chest radiography was applied to quantify lung-involvement volume using retrospective examinations of 50 patients who were diagnosed with pulmonary TB and treated with two different drugs schemes. Twenty-five patients were treated with Scheme I (rifampicin, isoniazid, and pyrazinamide), whereas twenty-five patients were treated with Scheme II (rifampicin, isoniazid, pyrazinamide, and ethambutol). Acute-phase reaction: Serum exams included C-reactive protein levels, erythrocyte sedimentation rate, and albumin levels. Pulmonary function was tested posttreatment. Results: We found strong agreement between lung involvement and serum indices pre- and posttreatment. Comparison of the functional severity degree with lung involvement based on 3D image quantification for both treatment schemes found a high correlation. Conclusions: The present 3D reconstruction method produced a satisfactory agreement with the acute-phase reaction, most notably a higher significance level with the C-reactive protein. We also found a quite reasonable coincidence between the 3D reconstruction method and the degree of functional lung impairment posttreatment. The performance of the quantification method was satisfactory when comparing the two treatment schemes. Thus, the 3D reconstruction quantification method may be useful tools for monitoring TB treatment. The association with serum indices are not only ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Venomous Animals and Toxins including Tropical Diseases 25 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Tuberculosis Quantification Lung involvement Serum tests Pulmonary function tests Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
spellingShingle |
Tuberculosis Quantification Lung involvement Serum tests Pulmonary function tests Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 Marcela de Oliveira Sergio Barbosa Duarte Guilherme Giacomini Paulo Câmara Marques Pereira Lenice do Rosário de Souza José Ricardo de Arruda Miranda Diana Rodrigues de Pina A lung image reconstruction from computed radiography images as a tool to tuberculosis treatment control |
topic_facet |
Tuberculosis Quantification Lung involvement Serum tests Pulmonary function tests Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
description |
Abstract Background: Background: Tuberculosis (TB) is an infectious lung disease with high worldwide incidence that severely compromises the quality of life in affected individuals. Clinical tests are currently employed to monitor pulmonary status and treatment progression. The present study aimed to apply a three-dimensional (3D) reconstruction method based on chest radiography to quantify lung-involvement volume of TB acute-phase patients before and after treatment. In addition, these results were compared with indices from conventional clinical exams to show the coincidence level. Methods: A 3D lung reconstruction method using patient chest radiography was applied to quantify lung-involvement volume using retrospective examinations of 50 patients who were diagnosed with pulmonary TB and treated with two different drugs schemes. Twenty-five patients were treated with Scheme I (rifampicin, isoniazid, and pyrazinamide), whereas twenty-five patients were treated with Scheme II (rifampicin, isoniazid, pyrazinamide, and ethambutol). Acute-phase reaction: Serum exams included C-reactive protein levels, erythrocyte sedimentation rate, and albumin levels. Pulmonary function was tested posttreatment. Results: We found strong agreement between lung involvement and serum indices pre- and posttreatment. Comparison of the functional severity degree with lung involvement based on 3D image quantification for both treatment schemes found a high correlation. Conclusions: The present 3D reconstruction method produced a satisfactory agreement with the acute-phase reaction, most notably a higher significance level with the C-reactive protein. We also found a quite reasonable coincidence between the 3D reconstruction method and the degree of functional lung impairment posttreatment. The performance of the quantification method was satisfactory when comparing the two treatment schemes. Thus, the 3D reconstruction quantification method may be useful tools for monitoring TB treatment. The association with serum indices are not only ... |
format |
Article in Journal/Newspaper |
author |
Marcela de Oliveira Sergio Barbosa Duarte Guilherme Giacomini Paulo Câmara Marques Pereira Lenice do Rosário de Souza José Ricardo de Arruda Miranda Diana Rodrigues de Pina |
author_facet |
Marcela de Oliveira Sergio Barbosa Duarte Guilherme Giacomini Paulo Câmara Marques Pereira Lenice do Rosário de Souza José Ricardo de Arruda Miranda Diana Rodrigues de Pina |
author_sort |
Marcela de Oliveira |
title |
A lung image reconstruction from computed radiography images as a tool to tuberculosis treatment control |
title_short |
A lung image reconstruction from computed radiography images as a tool to tuberculosis treatment control |
title_full |
A lung image reconstruction from computed radiography images as a tool to tuberculosis treatment control |
title_fullStr |
A lung image reconstruction from computed radiography images as a tool to tuberculosis treatment control |
title_full_unstemmed |
A lung image reconstruction from computed radiography images as a tool to tuberculosis treatment control |
title_sort |
lung image reconstruction from computed radiography images as a tool to tuberculosis treatment control |
publisher |
SciELO |
publishDate |
2019 |
url |
https://doi.org/10.1590/1678-9199-jvatitd-1449-18 https://doaj.org/article/32be3e333b984431909015b8f955dd23 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 25, Iss 0 (2019) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100302&lng=en&tlng=en https://doaj.org/toc/1678-9199 1678-9199 doi:10.1590/1678-9199-jvatitd-1449-18 https://doaj.org/article/32be3e333b984431909015b8f955dd23 |
op_doi |
https://doi.org/10.1590/1678-9199-jvatitd-1449-18 |
container_title |
Journal of Venomous Animals and Toxins including Tropical Diseases |
container_volume |
25 |
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1766346307711008768 |