Anti-Toxocara antibodies detected in children attending elementary school in Vitoria, State of Espírito Santo, Brazil: prevalence and associated factors
INTRODUCTION: The aim of this study was to evaluate the frequency of anti-Toxocara antibodies in serum from 7-year-old children attending elementary school in Vitória-ES, Brazil and to correlate these antibodies with socio-demographic factors, the presence of intestinal helminths, blood eosinophil n...
Published in: | Revista da Sociedade Brasileira de Medicina Tropical |
---|---|
Main Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Sociedade Brasileira de Medicina Tropical (SBMT)
2011
|
Subjects: | |
Online Access: | https://doi.org/10.1590/S0037-86822011000400012 https://doaj.org/article/329e467862db499391a2ce44864c6f28 |
id |
ftdoajarticles:oai:doaj.org/article:329e467862db499391a2ce44864c6f28 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:329e467862db499391a2ce44864c6f28 2023-05-15T15:11:30+02:00 Anti-Toxocara antibodies detected in children attending elementary school in Vitoria, State of Espírito Santo, Brazil: prevalence and associated factors Roberta Paranhos Fragoso Mariza Buriche Macedo Monteiro Elenice Moreira Lemos Fausto Edmundo Lima Pereira 2011-08-01T00:00:00Z https://doi.org/10.1590/S0037-86822011000400012 https://doaj.org/article/329e467862db499391a2ce44864c6f28 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000400012&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/S0037-86822011000400012 https://doaj.org/article/329e467862db499391a2ce44864c6f28 Revista da Sociedade Brasileira de Medicina Tropical, Vol 44, Iss 4, Pp 461-466 (2011) Toxocara canis Toxocarase Infecção com Toxocara Larva migrans visceral Arctic medicine. Tropical medicine RC955-962 article 2011 ftdoajarticles https://doi.org/10.1590/S0037-86822011000400012 2022-12-31T03:20:45Z INTRODUCTION: The aim of this study was to evaluate the frequency of anti-Toxocara antibodies in serum from 7-year-old children attending elementary school in Vitória-ES, Brazil and to correlate these antibodies with socio-demographic factors, the presence of intestinal helminths, blood eosinophil numbers, past history of allergy or asthma, and clinical manifestations of helminth infections. METHODS: The detection of anti-Toxocara antibodies was performed using an ELISA (Cellabs Pty Ltd)on serum from 391 children who had already been examined by fecal examination and blood cell counts. Data from clinical and physical examinations were obtained for all children. RESULTS: The prevalence of anti-Toxocara antibodies was 51.6%, with no gender differences. No significant differences were observed between positive serology and the presence or absence of intestinal worms (60.3 and 51.7%, respectively; p = 0.286). The only variables significantly related to positive serology were onycophagy and the use of unfiltered water. Although eosinophilia (blood eosinophil count higher than 600/mm³) was significantly related to the presence of a positive ELISA result, this significance disappeared when we considered only children without worms or without a past history of allergy or asthma. No clinical symptoms related to Toxocara infection were observed. CONCLUSIONS: There is a high prevalence of anti-Toxocara antibodies in children attending elementary schools in Vitória, which may be partially related to cross-reactivity with intestinal helminths or to a high frequency of infection with a small number of Toxocara eggs. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 44 4 461 466 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Toxocara canis Toxocarase Infecção com Toxocara Larva migrans visceral Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Toxocara canis Toxocarase Infecção com Toxocara Larva migrans visceral Arctic medicine. Tropical medicine RC955-962 Roberta Paranhos Fragoso Mariza Buriche Macedo Monteiro Elenice Moreira Lemos Fausto Edmundo Lima Pereira Anti-Toxocara antibodies detected in children attending elementary school in Vitoria, State of Espírito Santo, Brazil: prevalence and associated factors |
topic_facet |
Toxocara canis Toxocarase Infecção com Toxocara Larva migrans visceral Arctic medicine. Tropical medicine RC955-962 |
description |
INTRODUCTION: The aim of this study was to evaluate the frequency of anti-Toxocara antibodies in serum from 7-year-old children attending elementary school in Vitória-ES, Brazil and to correlate these antibodies with socio-demographic factors, the presence of intestinal helminths, blood eosinophil numbers, past history of allergy or asthma, and clinical manifestations of helminth infections. METHODS: The detection of anti-Toxocara antibodies was performed using an ELISA (Cellabs Pty Ltd)on serum from 391 children who had already been examined by fecal examination and blood cell counts. Data from clinical and physical examinations were obtained for all children. RESULTS: The prevalence of anti-Toxocara antibodies was 51.6%, with no gender differences. No significant differences were observed between positive serology and the presence or absence of intestinal worms (60.3 and 51.7%, respectively; p = 0.286). The only variables significantly related to positive serology were onycophagy and the use of unfiltered water. Although eosinophilia (blood eosinophil count higher than 600/mm³) was significantly related to the presence of a positive ELISA result, this significance disappeared when we considered only children without worms or without a past history of allergy or asthma. No clinical symptoms related to Toxocara infection were observed. CONCLUSIONS: There is a high prevalence of anti-Toxocara antibodies in children attending elementary schools in Vitória, which may be partially related to cross-reactivity with intestinal helminths or to a high frequency of infection with a small number of Toxocara eggs. |
format |
Article in Journal/Newspaper |
author |
Roberta Paranhos Fragoso Mariza Buriche Macedo Monteiro Elenice Moreira Lemos Fausto Edmundo Lima Pereira |
author_facet |
Roberta Paranhos Fragoso Mariza Buriche Macedo Monteiro Elenice Moreira Lemos Fausto Edmundo Lima Pereira |
author_sort |
Roberta Paranhos Fragoso |
title |
Anti-Toxocara antibodies detected in children attending elementary school in Vitoria, State of Espírito Santo, Brazil: prevalence and associated factors |
title_short |
Anti-Toxocara antibodies detected in children attending elementary school in Vitoria, State of Espírito Santo, Brazil: prevalence and associated factors |
title_full |
Anti-Toxocara antibodies detected in children attending elementary school in Vitoria, State of Espírito Santo, Brazil: prevalence and associated factors |
title_fullStr |
Anti-Toxocara antibodies detected in children attending elementary school in Vitoria, State of Espírito Santo, Brazil: prevalence and associated factors |
title_full_unstemmed |
Anti-Toxocara antibodies detected in children attending elementary school in Vitoria, State of Espírito Santo, Brazil: prevalence and associated factors |
title_sort |
anti-toxocara antibodies detected in children attending elementary school in vitoria, state of espírito santo, brazil: prevalence and associated factors |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2011 |
url |
https://doi.org/10.1590/S0037-86822011000400012 https://doaj.org/article/329e467862db499391a2ce44864c6f28 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 44, Iss 4, Pp 461-466 (2011) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000400012&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/S0037-86822011000400012 https://doaj.org/article/329e467862db499391a2ce44864c6f28 |
op_doi |
https://doi.org/10.1590/S0037-86822011000400012 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
container_volume |
44 |
container_issue |
4 |
container_start_page |
461 |
op_container_end_page |
466 |
_version_ |
1766342346720411648 |