A survey on Mycobacterium ulcerans in Mosquitoes and March flies captured from endemic areas of Northern Queensland, Australia.
Mycobacterium ulcerans is the causative agent of Buruli ulcer (BU). This nontuberculous mycobacterial infection has been reported in 34 countries worldwide. In Australia, the majority of cases of BU have been recorded in coastal Victoria and the Mossman-Daintree areas of north Queensland. Mosquitoes...
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ftdoajarticles:oai:doaj.org/article:316b81979c1d4c2c92715b7dc4921e59 2023-05-15T15:06:24+02:00 A survey on Mycobacterium ulcerans in Mosquitoes and March flies captured from endemic areas of Northern Queensland, Australia. Avishek Singh William John Hannan McBride Brenda Govan Mark Pearson Scott A Ritchie 2019-02-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0006745 https://doaj.org/article/316b81979c1d4c2c92715b7dc4921e59 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC6400404?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0006745 https://doaj.org/article/316b81979c1d4c2c92715b7dc4921e59 PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0006745 (2019) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2019 ftdoajarticles https://doi.org/10.1371/journal.pntd.0006745 2022-12-31T03:21:49Z Mycobacterium ulcerans is the causative agent of Buruli ulcer (BU). This nontuberculous mycobacterial infection has been reported in 34 countries worldwide. In Australia, the majority of cases of BU have been recorded in coastal Victoria and the Mossman-Daintree areas of north Queensland. Mosquitoes have been postulated as a vector of M. ulcerans in Victoria, however the specific mode of transmission of this disease is still far from being well understood. In the current study, we trapped and analysed 16,900 (allocated to 845 pools) mosquitoes and 296 March flies from the endemic areas of north Queensland to examine for the presence of M. ulcerans DNA by polymerase chain reaction. Seven of 845 pools of mosquitoes were positive on screening using the IS2404 PCR target (maximum likelihood estimate 0.4/1,000). M. ulcerans DNA was detected from one pool of mosquitoes from which all three PCR targets: IS2404, IS2606 and the ketoreductase B domain of mycolactone polyketide synthase gene were detected. None of the March fly samples were positive for the presence of M. ulcerans DNA. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Queensland Mossman ENVELOPE(-44.700,-44.700,-60.750,-60.750) PLOS Neglected Tropical Diseases 13 2 e0006745 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Avishek Singh William John Hannan McBride Brenda Govan Mark Pearson Scott A Ritchie A survey on Mycobacterium ulcerans in Mosquitoes and March flies captured from endemic areas of Northern Queensland, Australia. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Mycobacterium ulcerans is the causative agent of Buruli ulcer (BU). This nontuberculous mycobacterial infection has been reported in 34 countries worldwide. In Australia, the majority of cases of BU have been recorded in coastal Victoria and the Mossman-Daintree areas of north Queensland. Mosquitoes have been postulated as a vector of M. ulcerans in Victoria, however the specific mode of transmission of this disease is still far from being well understood. In the current study, we trapped and analysed 16,900 (allocated to 845 pools) mosquitoes and 296 March flies from the endemic areas of north Queensland to examine for the presence of M. ulcerans DNA by polymerase chain reaction. Seven of 845 pools of mosquitoes were positive on screening using the IS2404 PCR target (maximum likelihood estimate 0.4/1,000). M. ulcerans DNA was detected from one pool of mosquitoes from which all three PCR targets: IS2404, IS2606 and the ketoreductase B domain of mycolactone polyketide synthase gene were detected. None of the March fly samples were positive for the presence of M. ulcerans DNA. |
format |
Article in Journal/Newspaper |
author |
Avishek Singh William John Hannan McBride Brenda Govan Mark Pearson Scott A Ritchie |
author_facet |
Avishek Singh William John Hannan McBride Brenda Govan Mark Pearson Scott A Ritchie |
author_sort |
Avishek Singh |
title |
A survey on Mycobacterium ulcerans in Mosquitoes and March flies captured from endemic areas of Northern Queensland, Australia. |
title_short |
A survey on Mycobacterium ulcerans in Mosquitoes and March flies captured from endemic areas of Northern Queensland, Australia. |
title_full |
A survey on Mycobacterium ulcerans in Mosquitoes and March flies captured from endemic areas of Northern Queensland, Australia. |
title_fullStr |
A survey on Mycobacterium ulcerans in Mosquitoes and March flies captured from endemic areas of Northern Queensland, Australia. |
title_full_unstemmed |
A survey on Mycobacterium ulcerans in Mosquitoes and March flies captured from endemic areas of Northern Queensland, Australia. |
title_sort |
survey on mycobacterium ulcerans in mosquitoes and march flies captured from endemic areas of northern queensland, australia. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2019 |
url |
https://doi.org/10.1371/journal.pntd.0006745 https://doaj.org/article/316b81979c1d4c2c92715b7dc4921e59 |
long_lat |
ENVELOPE(-44.700,-44.700,-60.750,-60.750) |
geographic |
Arctic Queensland Mossman |
geographic_facet |
Arctic Queensland Mossman |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0006745 (2019) |
op_relation |
http://europepmc.org/articles/PMC6400404?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0006745 https://doaj.org/article/316b81979c1d4c2c92715b7dc4921e59 |
op_doi |
https://doi.org/10.1371/journal.pntd.0006745 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
13 |
container_issue |
2 |
container_start_page |
e0006745 |
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1766338013862821888 |