Comparison of Schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections.
A Schistosoma mansoni cercarial antigen preparation (cercarial transformation fluid--SmCTF) was evaluated for detection of anti-schistosome antibodies in human sera in 4 collaborating laboratories. The performance of SmCTF was compared with that of S. mansoni egg antigens (SmSEA) in an indirect enzy...
Published in: | PLoS Neglected Tropical Diseases |
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ftdoajarticles:oai:doaj.org/article:3159512c7bdc4b5da4df0abc16bae088 2023-05-15T15:05:03+02:00 Comparison of Schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections. Huw Smith Mike Doenhoff Cara Aitken Wendi Bailey Minjun Ji Emily Dawson Henk Gilis Grant Spence Claire Alexander Tom van Gool 2012-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0001815 https://doaj.org/article/3159512c7bdc4b5da4df0abc16bae088 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3441401?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 doi:10.1371/journal.pntd.0001815 1935-2727 1935-2735 https://doaj.org/article/3159512c7bdc4b5da4df0abc16bae088 PLoS Neglected Tropical Diseases, Vol 6, Iss 9, p e1815 (2012) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2012 ftdoajarticles https://doi.org/10.1371/journal.pntd.0001815 2022-12-31T00:56:10Z A Schistosoma mansoni cercarial antigen preparation (cercarial transformation fluid--SmCTF) was evaluated for detection of anti-schistosome antibodies in human sera in 4 collaborating laboratories. The performance of SmCTF was compared with that of S. mansoni egg antigens (SmSEA) in an indirect enzyme-immunoassay (ELISA) antigen assay, the latter being used routinely in 3 of the 4 participating laboratories to diagnose S. mansoni and S. haematobium infections. In the fourth laboratory the performance of SmCTF was compared with that of S. japonicum egg antigens (SjSEA) in ELISA for detection of anti-S. japonicum antibodies. In all 4 laboratories the results given by SmCTF in ELISA were very similar to those given by the antigen preparation routinely used in the respective laboratory to detect anti-schistosome antibodies in human infection sera. In so far as the ELISA results from SmCTF are thus so little different from those given by schistosome egg antigens and also cheaper to produce, the former is a potentially useful new diagnostic aid for schistosomiasis. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 6 9 e1815 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Huw Smith Mike Doenhoff Cara Aitken Wendi Bailey Minjun Ji Emily Dawson Henk Gilis Grant Spence Claire Alexander Tom van Gool Comparison of Schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
A Schistosoma mansoni cercarial antigen preparation (cercarial transformation fluid--SmCTF) was evaluated for detection of anti-schistosome antibodies in human sera in 4 collaborating laboratories. The performance of SmCTF was compared with that of S. mansoni egg antigens (SmSEA) in an indirect enzyme-immunoassay (ELISA) antigen assay, the latter being used routinely in 3 of the 4 participating laboratories to diagnose S. mansoni and S. haematobium infections. In the fourth laboratory the performance of SmCTF was compared with that of S. japonicum egg antigens (SjSEA) in ELISA for detection of anti-S. japonicum antibodies. In all 4 laboratories the results given by SmCTF in ELISA were very similar to those given by the antigen preparation routinely used in the respective laboratory to detect anti-schistosome antibodies in human infection sera. In so far as the ELISA results from SmCTF are thus so little different from those given by schistosome egg antigens and also cheaper to produce, the former is a potentially useful new diagnostic aid for schistosomiasis. |
format |
Article in Journal/Newspaper |
author |
Huw Smith Mike Doenhoff Cara Aitken Wendi Bailey Minjun Ji Emily Dawson Henk Gilis Grant Spence Claire Alexander Tom van Gool |
author_facet |
Huw Smith Mike Doenhoff Cara Aitken Wendi Bailey Minjun Ji Emily Dawson Henk Gilis Grant Spence Claire Alexander Tom van Gool |
author_sort |
Huw Smith |
title |
Comparison of Schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections. |
title_short |
Comparison of Schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections. |
title_full |
Comparison of Schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections. |
title_fullStr |
Comparison of Schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections. |
title_full_unstemmed |
Comparison of Schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections. |
title_sort |
comparison of schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2012 |
url |
https://doi.org/10.1371/journal.pntd.0001815 https://doaj.org/article/3159512c7bdc4b5da4df0abc16bae088 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 6, Iss 9, p e1815 (2012) |
op_relation |
http://europepmc.org/articles/PMC3441401?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 doi:10.1371/journal.pntd.0001815 1935-2727 1935-2735 https://doaj.org/article/3159512c7bdc4b5da4df0abc16bae088 |
op_doi |
https://doi.org/10.1371/journal.pntd.0001815 |
container_title |
PLoS Neglected Tropical Diseases |
container_volume |
6 |
container_issue |
9 |
container_start_page |
e1815 |
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1766336813271613440 |