Glucose metabolism sustains heme-induced Trypanosoma cruzi epimastigote growth in vitro.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Carolina Silva Dias Vieira, Ramon Pinheiro Aguiar, Natalia Pereira de Almeida Nogueira, Gilson Costa Dos Santos Junior, Marcia Cristina Paes
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2023
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Crabtree
• Online Access: https://doi.org/10.1371/journal.pntd.0011725; https://doaj.org/article/31594309491a40f198f086c8bdba6d7a

Chagas disease is caused by the protozoan parasite, Trypanosoma cruzi. This parasite alternates between an insect vector and a mammalian host. T. cruzi epimastigotes reside in the insect vector and coexist with the blood components of the vertebrate host. The metabolic profile of T. cruzi has been e...