Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets
The effects of high and low-protein diets on the structure of the jejunal mucosa were studied in Schistosoma mansoni infected mice (morphology and histomorphometry). Weaning male albino mice were infected with 80 cercariae, fed with high (20%) or low-protein (5%) diets and compared to uninfected con...
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Sociedade Brasileira de Medicina Tropical (SBMT)
2002
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ftdoajarticles:oai:doaj.org/article:3101e11a0bca40a29cb685881fdd62d2 2023-05-15T15:04:29+02:00 Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets Janira Lúcia Assumpção Couto Haroldo da Silva Ferreira Dinalva Bezerra da Rocha Maria Eugênia Leite Duarte Monica Lopes Assunção Eridan de Medeiros Coutinho 2002-12-01T00:00:00Z https://doaj.org/article/3101e11a0bca40a29cb685881fdd62d2 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000600010&tlng=en https://doaj.org/toc/1678-9849 1678-9849 https://doaj.org/article/3101e11a0bca40a29cb685881fdd62d2 Revista da Sociedade Brasileira de Medicina Tropical, Vol 35, Iss 6, Pp 601-607 (2002) Schistosoma mansoni Undernutrition Mice Intestinal mucosa Histomorphometry Arctic medicine. Tropical medicine RC955-962 article 2002 ftdoajarticles 2022-12-30T21:39:04Z The effects of high and low-protein diets on the structure of the jejunal mucosa were studied in Schistosoma mansoni infected mice (morphology and histomorphometry). Weaning male albino mice were infected with 80 cercariae, fed with high (20%) or low-protein (5%) diets and compared to uninfected controls under the same conditions. Mice were sacrificed 12 weeks after infection. Animals submitted to a low-protein diet showed lower weight curves, mainly when infected. In the jejunal mucosa, finger-like villi were the predominant pattern among uninfected high-protein fed animals, while the infected ones showed leaf-shaped and flattened villi in most cases. Undernourished infected mice had 65.7% leaf-shaped villi. A significant increase in the number of goblet cells was seen in infected mice. A decrease in the number of absorptive cells was detected in undernourished mice, particularly in infected ones. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Schistosoma mansoni Undernutrition Mice Intestinal mucosa Histomorphometry Arctic medicine. Tropical medicine RC955-962 |
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Schistosoma mansoni Undernutrition Mice Intestinal mucosa Histomorphometry Arctic medicine. Tropical medicine RC955-962 Janira Lúcia Assumpção Couto Haroldo da Silva Ferreira Dinalva Bezerra da Rocha Maria Eugênia Leite Duarte Monica Lopes Assunção Eridan de Medeiros Coutinho Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets |
topic_facet |
Schistosoma mansoni Undernutrition Mice Intestinal mucosa Histomorphometry Arctic medicine. Tropical medicine RC955-962 |
description |
The effects of high and low-protein diets on the structure of the jejunal mucosa were studied in Schistosoma mansoni infected mice (morphology and histomorphometry). Weaning male albino mice were infected with 80 cercariae, fed with high (20%) or low-protein (5%) diets and compared to uninfected controls under the same conditions. Mice were sacrificed 12 weeks after infection. Animals submitted to a low-protein diet showed lower weight curves, mainly when infected. In the jejunal mucosa, finger-like villi were the predominant pattern among uninfected high-protein fed animals, while the infected ones showed leaf-shaped and flattened villi in most cases. Undernourished infected mice had 65.7% leaf-shaped villi. A significant increase in the number of goblet cells was seen in infected mice. A decrease in the number of absorptive cells was detected in undernourished mice, particularly in infected ones. |
format |
Article in Journal/Newspaper |
author |
Janira Lúcia Assumpção Couto Haroldo da Silva Ferreira Dinalva Bezerra da Rocha Maria Eugênia Leite Duarte Monica Lopes Assunção Eridan de Medeiros Coutinho |
author_facet |
Janira Lúcia Assumpção Couto Haroldo da Silva Ferreira Dinalva Bezerra da Rocha Maria Eugênia Leite Duarte Monica Lopes Assunção Eridan de Medeiros Coutinho |
author_sort |
Janira Lúcia Assumpção Couto |
title |
Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets |
title_short |
Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets |
title_full |
Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets |
title_fullStr |
Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets |
title_full_unstemmed |
Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets |
title_sort |
structural changes in the jejunal mucosa of mice infected with schistosoma mansoni, fed low or high protein diets |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2002 |
url |
https://doaj.org/article/3101e11a0bca40a29cb685881fdd62d2 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 35, Iss 6, Pp 601-607 (2002) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000600010&tlng=en https://doaj.org/toc/1678-9849 1678-9849 https://doaj.org/article/3101e11a0bca40a29cb685881fdd62d2 |
_version_ |
1766336245077639168 |