Bendiocarb, a potential alternative against pyrethroid resistant Anopheles gambiae in Benin, West Africa
Abstract Background Anopheles gambiae , the main malaria vector in Benin has developed high level of resistance to pyrethroid insecticides, which is a serious concern to the future use of long-lasting insecticidal nets (LLIN) and indoor residual spraying (IRS). In this context, one of the pathways a...
Published in: | Malaria Journal |
---|---|
Main Authors: | , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
BMC
2010
|
Subjects: | |
Online Access: | https://doi.org/10.1186/1475-2875-9-204 https://doaj.org/article/30fc1be4dafc4cb0b13f2a9677bc5d2e |
id |
ftdoajarticles:oai:doaj.org/article:30fc1be4dafc4cb0b13f2a9677bc5d2e |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:30fc1be4dafc4cb0b13f2a9677bc5d2e 2023-05-15T15:15:36+02:00 Bendiocarb, a potential alternative against pyrethroid resistant Anopheles gambiae in Benin, West Africa Irish Seth Gbénou Dina Padonou Gil Akogbéto Martin C Yadouleton Anges 2010-07-01T00:00:00Z https://doi.org/10.1186/1475-2875-9-204 https://doaj.org/article/30fc1be4dafc4cb0b13f2a9677bc5d2e EN eng BMC http://www.malariajournal.com/content/9/1/204 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-204 1475-2875 https://doaj.org/article/30fc1be4dafc4cb0b13f2a9677bc5d2e Malaria Journal, Vol 9, Iss 1, p 204 (2010) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2010 ftdoajarticles https://doi.org/10.1186/1475-2875-9-204 2022-12-31T05:18:14Z Abstract Background Anopheles gambiae , the main malaria vector in Benin has developed high level of resistance to pyrethroid insecticides, which is a serious concern to the future use of long-lasting insecticidal nets (LLIN) and indoor residual spraying (IRS). In this context, one of the pathways available for malaria vector control would be to investigate alternative classes of insecticides with different mode of action than that of pyrethroids. The goal of this study was to evaluate under field conditions the efficacy of a carbamate (bendiocarb) and an organophosphate (fenitrothion) against pyrethroid-resistant An. gambiae s.s . Methods Wild populations and females from laboratory colonies of five days old An. gambiae were bio-assayed during this study. Two pyrethroids (deltamethrin and alphacypermethrin), an organophosphate (fenitrothion), a carbamate (bendiocarb) and a mixture of an organophosphate (chlorpyriphos + a pyrethroid deltamethrin) were compared in experimental huts as IRS treatments. Insecticides were applied in the huts using a hand-operated compression sprayer. The deterrency, exophily, blood feeding rate and mortality induced by these insecticides against An. gambiae were compared to the untreated control huts. Results Deltamethrin, alphacypermethrin and bendiocarb treatment significantly reduced mosquito entry into the huts (p < 0.05) compared to untreated huts. Blood feeding rates in huts treated with fenitrothion and the mixture chlorpyriphos/deltamethrin were reduced from 10.95% respectively to 3.7% and 4.47% three months after treatment and from 10.20% to 4.4% and 2.04% four months after treatment. Exophily rates in huts with deltamethrin, alphacypermethrin and the mixture chlorpyriphos/deltamethrin were significantly higher than in the huts with fenitrothion. Deltamethrin and alphacypermethrin had the lowest mortality rate while fenitrothion killed 100% of An. gambiae (in the first month) and 77.8% (in the fourth month). Bendiocarb and the mixture chlorpyriphos/deltamethrin mortality ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 9 1 204 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Irish Seth Gbénou Dina Padonou Gil Akogbéto Martin C Yadouleton Anges Bendiocarb, a potential alternative against pyrethroid resistant Anopheles gambiae in Benin, West Africa |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Anopheles gambiae , the main malaria vector in Benin has developed high level of resistance to pyrethroid insecticides, which is a serious concern to the future use of long-lasting insecticidal nets (LLIN) and indoor residual spraying (IRS). In this context, one of the pathways available for malaria vector control would be to investigate alternative classes of insecticides with different mode of action than that of pyrethroids. The goal of this study was to evaluate under field conditions the efficacy of a carbamate (bendiocarb) and an organophosphate (fenitrothion) against pyrethroid-resistant An. gambiae s.s . Methods Wild populations and females from laboratory colonies of five days old An. gambiae were bio-assayed during this study. Two pyrethroids (deltamethrin and alphacypermethrin), an organophosphate (fenitrothion), a carbamate (bendiocarb) and a mixture of an organophosphate (chlorpyriphos + a pyrethroid deltamethrin) were compared in experimental huts as IRS treatments. Insecticides were applied in the huts using a hand-operated compression sprayer. The deterrency, exophily, blood feeding rate and mortality induced by these insecticides against An. gambiae were compared to the untreated control huts. Results Deltamethrin, alphacypermethrin and bendiocarb treatment significantly reduced mosquito entry into the huts (p < 0.05) compared to untreated huts. Blood feeding rates in huts treated with fenitrothion and the mixture chlorpyriphos/deltamethrin were reduced from 10.95% respectively to 3.7% and 4.47% three months after treatment and from 10.20% to 4.4% and 2.04% four months after treatment. Exophily rates in huts with deltamethrin, alphacypermethrin and the mixture chlorpyriphos/deltamethrin were significantly higher than in the huts with fenitrothion. Deltamethrin and alphacypermethrin had the lowest mortality rate while fenitrothion killed 100% of An. gambiae (in the first month) and 77.8% (in the fourth month). Bendiocarb and the mixture chlorpyriphos/deltamethrin mortality ... |
format |
Article in Journal/Newspaper |
author |
Irish Seth Gbénou Dina Padonou Gil Akogbéto Martin C Yadouleton Anges |
author_facet |
Irish Seth Gbénou Dina Padonou Gil Akogbéto Martin C Yadouleton Anges |
author_sort |
Irish Seth |
title |
Bendiocarb, a potential alternative against pyrethroid resistant Anopheles gambiae in Benin, West Africa |
title_short |
Bendiocarb, a potential alternative against pyrethroid resistant Anopheles gambiae in Benin, West Africa |
title_full |
Bendiocarb, a potential alternative against pyrethroid resistant Anopheles gambiae in Benin, West Africa |
title_fullStr |
Bendiocarb, a potential alternative against pyrethroid resistant Anopheles gambiae in Benin, West Africa |
title_full_unstemmed |
Bendiocarb, a potential alternative against pyrethroid resistant Anopheles gambiae in Benin, West Africa |
title_sort |
bendiocarb, a potential alternative against pyrethroid resistant anopheles gambiae in benin, west africa |
publisher |
BMC |
publishDate |
2010 |
url |
https://doi.org/10.1186/1475-2875-9-204 https://doaj.org/article/30fc1be4dafc4cb0b13f2a9677bc5d2e |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 9, Iss 1, p 204 (2010) |
op_relation |
http://www.malariajournal.com/content/9/1/204 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-204 1475-2875 https://doaj.org/article/30fc1be4dafc4cb0b13f2a9677bc5d2e |
op_doi |
https://doi.org/10.1186/1475-2875-9-204 |
container_title |
Malaria Journal |
container_volume |
9 |
container_issue |
1 |
container_start_page |
204 |
_version_ |
1766345963199266816 |