Clinical Symptoms, Imaging Features and Cyst Distribution in the Cerebrospinal Fluid Compartments in Patients with Extraparenchymal Neurocysticercosis.
Extraparenchymal neurocysticercosis has an aggressive course because cysts in the cerebrospinal fluid compartments induce acute inflammatory reactions. The relationships between symptoms, imaging findings, lesion type and location remain poorly understood. In this retrospective clinical records-base...
Published in: | PLOS Neglected Tropical Diseases |
---|---|
Main Authors: | , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pntd.0005115 https://doaj.org/article/30d8ccd2891f413097dcc0f8d7e23c44 |
id |
ftdoajarticles:oai:doaj.org/article:30d8ccd2891f413097dcc0f8d7e23c44 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:30d8ccd2891f413097dcc0f8d7e23c44 2023-05-15T15:09:24+02:00 Clinical Symptoms, Imaging Features and Cyst Distribution in the Cerebrospinal Fluid Compartments in Patients with Extraparenchymal Neurocysticercosis. Rodrigo Bazan Pedro Tadao Hamamoto Filho Gustavo José Luvizutto Hélio Rubens de Carvalho Nunes Newton Satoru Odashima Antônio Carlos Dos Santos Jorge Elias Júnior Marco Antônio Zanini Agnès Fleury Osvaldo Massaiti Takayanagui 2016-11-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0005115 https://doaj.org/article/30d8ccd2891f413097dcc0f8d7e23c44 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC5102378?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0005115 https://doaj.org/article/30d8ccd2891f413097dcc0f8d7e23c44 PLoS Neglected Tropical Diseases, Vol 10, Iss 11, p e0005115 (2016) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2016 ftdoajarticles https://doi.org/10.1371/journal.pntd.0005115 2022-12-31T16:24:22Z Extraparenchymal neurocysticercosis has an aggressive course because cysts in the cerebrospinal fluid compartments induce acute inflammatory reactions. The relationships between symptoms, imaging findings, lesion type and location remain poorly understood. In this retrospective clinical records-based study, we describe the clinical symptoms, magnetic resonance imaging features, and cyst distribution in the CSF compartments of 36 patients with extraparenchymal neurocysticercosis. Patients were recruited between 1995 and 2010 and median follow up was 38 months. During all the follow up time we found that 75% (27/36) of the patients had symptoms related to raised intracranial pressure sometime, 72.2% (26/36) cysticercotic meningitis, 61.1% (22/36) seizures, and 50.0% (18/36) headaches unrelated to intracranial pressure. Regarding lesion types, 77.8% (28/36) of patients presented with grape-like cysts, 22.2% (8/36) giant cysts, and 61.1% (22/36) contrast-enhancing lesions. Hydrocephalus occurred in 72.2% (26/36) of patients during the follow-up period. All patients had cysts in the subarachnoid space and 41.7% (15/36) had at least one cyst in some ventricle. Cysts were predominantly located in the posterior fossa (31 patients) and supratentorial basal cisterns (19 patients). The fourth ventricle was the main compromised ventricle (10 patients). Spinal cysts were more frequent than previously reported (11.1%, 4/36). Our findings are useful for both diagnosis and treatment selection in patients with neurocysticercosis. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Fossa ENVELOPE(9.795,9.795,62.990,62.990) PLOS Neglected Tropical Diseases 10 11 e0005115 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Rodrigo Bazan Pedro Tadao Hamamoto Filho Gustavo José Luvizutto Hélio Rubens de Carvalho Nunes Newton Satoru Odashima Antônio Carlos Dos Santos Jorge Elias Júnior Marco Antônio Zanini Agnès Fleury Osvaldo Massaiti Takayanagui Clinical Symptoms, Imaging Features and Cyst Distribution in the Cerebrospinal Fluid Compartments in Patients with Extraparenchymal Neurocysticercosis. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Extraparenchymal neurocysticercosis has an aggressive course because cysts in the cerebrospinal fluid compartments induce acute inflammatory reactions. The relationships between symptoms, imaging findings, lesion type and location remain poorly understood. In this retrospective clinical records-based study, we describe the clinical symptoms, magnetic resonance imaging features, and cyst distribution in the CSF compartments of 36 patients with extraparenchymal neurocysticercosis. Patients were recruited between 1995 and 2010 and median follow up was 38 months. During all the follow up time we found that 75% (27/36) of the patients had symptoms related to raised intracranial pressure sometime, 72.2% (26/36) cysticercotic meningitis, 61.1% (22/36) seizures, and 50.0% (18/36) headaches unrelated to intracranial pressure. Regarding lesion types, 77.8% (28/36) of patients presented with grape-like cysts, 22.2% (8/36) giant cysts, and 61.1% (22/36) contrast-enhancing lesions. Hydrocephalus occurred in 72.2% (26/36) of patients during the follow-up period. All patients had cysts in the subarachnoid space and 41.7% (15/36) had at least one cyst in some ventricle. Cysts were predominantly located in the posterior fossa (31 patients) and supratentorial basal cisterns (19 patients). The fourth ventricle was the main compromised ventricle (10 patients). Spinal cysts were more frequent than previously reported (11.1%, 4/36). Our findings are useful for both diagnosis and treatment selection in patients with neurocysticercosis. |
format |
Article in Journal/Newspaper |
author |
Rodrigo Bazan Pedro Tadao Hamamoto Filho Gustavo José Luvizutto Hélio Rubens de Carvalho Nunes Newton Satoru Odashima Antônio Carlos Dos Santos Jorge Elias Júnior Marco Antônio Zanini Agnès Fleury Osvaldo Massaiti Takayanagui |
author_facet |
Rodrigo Bazan Pedro Tadao Hamamoto Filho Gustavo José Luvizutto Hélio Rubens de Carvalho Nunes Newton Satoru Odashima Antônio Carlos Dos Santos Jorge Elias Júnior Marco Antônio Zanini Agnès Fleury Osvaldo Massaiti Takayanagui |
author_sort |
Rodrigo Bazan |
title |
Clinical Symptoms, Imaging Features and Cyst Distribution in the Cerebrospinal Fluid Compartments in Patients with Extraparenchymal Neurocysticercosis. |
title_short |
Clinical Symptoms, Imaging Features and Cyst Distribution in the Cerebrospinal Fluid Compartments in Patients with Extraparenchymal Neurocysticercosis. |
title_full |
Clinical Symptoms, Imaging Features and Cyst Distribution in the Cerebrospinal Fluid Compartments in Patients with Extraparenchymal Neurocysticercosis. |
title_fullStr |
Clinical Symptoms, Imaging Features and Cyst Distribution in the Cerebrospinal Fluid Compartments in Patients with Extraparenchymal Neurocysticercosis. |
title_full_unstemmed |
Clinical Symptoms, Imaging Features and Cyst Distribution in the Cerebrospinal Fluid Compartments in Patients with Extraparenchymal Neurocysticercosis. |
title_sort |
clinical symptoms, imaging features and cyst distribution in the cerebrospinal fluid compartments in patients with extraparenchymal neurocysticercosis. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2016 |
url |
https://doi.org/10.1371/journal.pntd.0005115 https://doaj.org/article/30d8ccd2891f413097dcc0f8d7e23c44 |
long_lat |
ENVELOPE(9.795,9.795,62.990,62.990) |
geographic |
Arctic Fossa |
geographic_facet |
Arctic Fossa |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 10, Iss 11, p e0005115 (2016) |
op_relation |
http://europepmc.org/articles/PMC5102378?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0005115 https://doaj.org/article/30d8ccd2891f413097dcc0f8d7e23c44 |
op_doi |
https://doi.org/10.1371/journal.pntd.0005115 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
10 |
container_issue |
11 |
container_start_page |
e0005115 |
_version_ |
1766340607631949824 |