Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients
Objective: To prove probable relations between serum E3 SUMO-protein ligase NSE2 (NSMCE2) concentration, peroxynitrite related to oxidative stress in nephrolithiasis patients. Methods: A total of 60 patients with nephrolithiasis and 50 healthy volunteers were involved in this study. Colorimetric met...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
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Online Access: | https://doi.org/10.1016/j.apjtb.2016.12.008 https://doaj.org/article/2fd3a11a150945b483daef2965532219 |
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ftdoajarticles:oai:doaj.org/article:2fd3a11a150945b483daef2965532219 2023-05-15T15:03:18+02:00 Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients Atheer Awad Mehde Faridah Yusof Wesen Adel Mehdi Raha Ahmed Raus Layla Othman Farhan Jwan Abdulmohsin Zainulabdeen Zaima Azira Zainal Abidin Hamid Ghazali Azlina Abd Rahman 2017-03-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2016.12.008 https://doaj.org/article/2fd3a11a150945b483daef2965532219 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169116302192 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2016.12.008 https://doaj.org/article/2fd3a11a150945b483daef2965532219 Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 3, Pp 249-252 (2017) Nephrolithiasis Peroxynitrite Nitric oxide E3 SUMO-protein ligase NSE2 Total oxidant status Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2017 ftdoajarticles https://doi.org/10.1016/j.apjtb.2016.12.008 2022-12-31T04:35:45Z Objective: To prove probable relations between serum E3 SUMO-protein ligase NSE2 (NSMCE2) concentration, peroxynitrite related to oxidative stress in nephrolithiasis patients. Methods: A total of 60 patients with nephrolithiasis and 50 healthy volunteers were involved in this study. Colorimetric method was used to detect blood urea, creatinine, uric acid, protein, albumin, total antioxidant status, total oxidant status, peroxynitrite, nitric oxide and oxidative stress index. Glutathione, NSMCE2 and superoxide dismutase were measured by ELISA. Results: A significant increase in level of peroxynitrite, total oxidant status, NSMCE2 and oxidative stress index in patients was observed, while total antioxidant status and glutathione were significantly decreased. Conclusions: The study concluded that serum NSMCE2 significantly correlated with peroxynitrite and oxidative stress in patients with nephrolithiasis. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 7 3 249 252 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Nephrolithiasis Peroxynitrite Nitric oxide E3 SUMO-protein ligase NSE2 Total oxidant status Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Nephrolithiasis Peroxynitrite Nitric oxide E3 SUMO-protein ligase NSE2 Total oxidant status Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Atheer Awad Mehde Faridah Yusof Wesen Adel Mehdi Raha Ahmed Raus Layla Othman Farhan Jwan Abdulmohsin Zainulabdeen Zaima Azira Zainal Abidin Hamid Ghazali Azlina Abd Rahman Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients |
topic_facet |
Nephrolithiasis Peroxynitrite Nitric oxide E3 SUMO-protein ligase NSE2 Total oxidant status Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To prove probable relations between serum E3 SUMO-protein ligase NSE2 (NSMCE2) concentration, peroxynitrite related to oxidative stress in nephrolithiasis patients. Methods: A total of 60 patients with nephrolithiasis and 50 healthy volunteers were involved in this study. Colorimetric method was used to detect blood urea, creatinine, uric acid, protein, albumin, total antioxidant status, total oxidant status, peroxynitrite, nitric oxide and oxidative stress index. Glutathione, NSMCE2 and superoxide dismutase were measured by ELISA. Results: A significant increase in level of peroxynitrite, total oxidant status, NSMCE2 and oxidative stress index in patients was observed, while total antioxidant status and glutathione were significantly decreased. Conclusions: The study concluded that serum NSMCE2 significantly correlated with peroxynitrite and oxidative stress in patients with nephrolithiasis. |
format |
Article in Journal/Newspaper |
author |
Atheer Awad Mehde Faridah Yusof Wesen Adel Mehdi Raha Ahmed Raus Layla Othman Farhan Jwan Abdulmohsin Zainulabdeen Zaima Azira Zainal Abidin Hamid Ghazali Azlina Abd Rahman |
author_facet |
Atheer Awad Mehde Faridah Yusof Wesen Adel Mehdi Raha Ahmed Raus Layla Othman Farhan Jwan Abdulmohsin Zainulabdeen Zaima Azira Zainal Abidin Hamid Ghazali Azlina Abd Rahman |
author_sort |
Atheer Awad Mehde |
title |
Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients |
title_short |
Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients |
title_full |
Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients |
title_fullStr |
Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients |
title_full_unstemmed |
Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients |
title_sort |
serum e3 sumo-protein ligase nse2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2017 |
url |
https://doi.org/10.1016/j.apjtb.2016.12.008 https://doaj.org/article/2fd3a11a150945b483daef2965532219 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 3, Pp 249-252 (2017) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169116302192 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2016.12.008 https://doaj.org/article/2fd3a11a150945b483daef2965532219 |
op_doi |
https://doi.org/10.1016/j.apjtb.2016.12.008 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
7 |
container_issue |
3 |
container_start_page |
249 |
op_container_end_page |
252 |
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1766335167675236352 |