Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca
Long-standing reports of open sores on the hind legs of moose (Alces alces) have been recorded in Alaska (as well as Canada, Europe, and Michigan), eliciting concerns about causes and infection. We used histological and genomic methods to investigate the sores from 20 adult moose on the Kenai Penins...
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ftdoajarticles:oai:doaj.org/article:2faccdb030b94aca8662af98e8c0b00c 2023-05-15T13:13:18+02:00 Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca Bridgett M. Benedict Perry S. Barboza John A. Crouse Katia R. Groch Matthew R. Kulpa Dan P. Thompson Guilherme G. Verocai Dominique J. Wiener 2023-01-01T00:00:00Z https://doaj.org/article/2faccdb030b94aca8662af98e8c0b00c EN eng Public Library of Science (PLoS) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833588/?tool=EBI https://doaj.org/toc/1932-6203 1932-6203 https://doaj.org/article/2faccdb030b94aca8662af98e8c0b00c PLoS ONE, Vol 18, Iss 1 (2023) Medicine R Science Q article 2023 ftdoajarticles 2023-01-22T01:42:06Z Long-standing reports of open sores on the hind legs of moose (Alces alces) have been recorded in Alaska (as well as Canada, Europe, and Michigan), eliciting concerns about causes and infection. We used histological and genomic methods to investigate the sores from 20 adult moose on the Kenai Peninsula, Alaska. We paired this with thermal imagery and molt scoring of adult moose to further describe sore formation and understand its timing. Severe, ulcerative and eosinophilic dermatitis was found in all moose with sores present, and microfilariae within intraepidermal pustules were additionally found in four samples. Genetic analysis of sores from moose revealed a previously unknown genetic lineage of Onchocerca. Adult moose molt and lose their barrier of protection against flies in June and July during peak fly activity, leaving them vulnerable and allowing the development of sores. In summary, our results indicate that the cause for the sores on the hindleg of moose is a previously unknown genetic lineage of Onchocerca, probably transmitted by black flies, in timing with the molt cycle of adult moose. These sores leave moose exposed to pathogens, making them vulnerable, and challenging their health and fitness. Article in Journal/Newspaper Alces alces Alaska Directory of Open Access Journals: DOAJ Articles Canada |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Medicine R Science Q |
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Medicine R Science Q Bridgett M. Benedict Perry S. Barboza John A. Crouse Katia R. Groch Matthew R. Kulpa Dan P. Thompson Guilherme G. Verocai Dominique J. Wiener Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca |
topic_facet |
Medicine R Science Q |
description |
Long-standing reports of open sores on the hind legs of moose (Alces alces) have been recorded in Alaska (as well as Canada, Europe, and Michigan), eliciting concerns about causes and infection. We used histological and genomic methods to investigate the sores from 20 adult moose on the Kenai Peninsula, Alaska. We paired this with thermal imagery and molt scoring of adult moose to further describe sore formation and understand its timing. Severe, ulcerative and eosinophilic dermatitis was found in all moose with sores present, and microfilariae within intraepidermal pustules were additionally found in four samples. Genetic analysis of sores from moose revealed a previously unknown genetic lineage of Onchocerca. Adult moose molt and lose their barrier of protection against flies in June and July during peak fly activity, leaving them vulnerable and allowing the development of sores. In summary, our results indicate that the cause for the sores on the hindleg of moose is a previously unknown genetic lineage of Onchocerca, probably transmitted by black flies, in timing with the molt cycle of adult moose. These sores leave moose exposed to pathogens, making them vulnerable, and challenging their health and fitness. |
format |
Article in Journal/Newspaper |
author |
Bridgett M. Benedict Perry S. Barboza John A. Crouse Katia R. Groch Matthew R. Kulpa Dan P. Thompson Guilherme G. Verocai Dominique J. Wiener |
author_facet |
Bridgett M. Benedict Perry S. Barboza John A. Crouse Katia R. Groch Matthew R. Kulpa Dan P. Thompson Guilherme G. Verocai Dominique J. Wiener |
author_sort |
Bridgett M. Benedict |
title |
Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca |
title_short |
Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca |
title_full |
Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca |
title_fullStr |
Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca |
title_full_unstemmed |
Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca |
title_sort |
sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus onchocerca |
publisher |
Public Library of Science (PLoS) |
publishDate |
2023 |
url |
https://doaj.org/article/2faccdb030b94aca8662af98e8c0b00c |
geographic |
Canada |
geographic_facet |
Canada |
genre |
Alces alces Alaska |
genre_facet |
Alces alces Alaska |
op_source |
PLoS ONE, Vol 18, Iss 1 (2023) |
op_relation |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833588/?tool=EBI https://doaj.org/toc/1932-6203 1932-6203 https://doaj.org/article/2faccdb030b94aca8662af98e8c0b00c |
_version_ |
1766257532243804160 |