Exploring the feasibility of introducing triple artemisinin-based combination therapy in the malaria treatment policy in Vietnam
Abstract Background This study investigates the processes regarding changing malaria treatment policies in Vietnam. Moreover, it explores the feasibility of introducing triple artemisinin-based combination therapy (TACT) in Vietnam to support the national malaria control and elimination plan. Method...
Published in: | Malaria Journal |
---|---|
Main Authors: | , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
BMC
2023
|
Subjects: | |
Online Access: | https://doi.org/10.1186/s12936-023-04763-4 https://doaj.org/article/2d66ede009644e0a8a8fb62360d26d0d |
id |
ftdoajarticles:oai:doaj.org/article:2d66ede009644e0a8a8fb62360d26d0d |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:2d66ede009644e0a8a8fb62360d26d0d 2023-12-03T10:18:11+01:00 Exploring the feasibility of introducing triple artemisinin-based combination therapy in the malaria treatment policy in Vietnam Van Anh Thi Cao Thieu Quang Nguyen Duong Le Quyen Wouter P. C. Boon Ellen H. M. Moors Arjen M. Dondorp Freek de Haan Chanaki Amaratunga 2023-10-01T00:00:00Z https://doi.org/10.1186/s12936-023-04763-4 https://doaj.org/article/2d66ede009644e0a8a8fb62360d26d0d EN eng BMC https://doi.org/10.1186/s12936-023-04763-4 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-023-04763-4 1475-2875 https://doaj.org/article/2d66ede009644e0a8a8fb62360d26d0d Malaria Journal, Vol 22, Iss 1, Pp 1-8 (2023) Triple artemisinin-based combination therapy (TACT) Introduction strategies Drug resistance Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2023 ftdoajarticles https://doi.org/10.1186/s12936-023-04763-4 2023-11-05T01:44:20Z Abstract Background This study investigates the processes regarding changing malaria treatment policies in Vietnam. Moreover, it explores the feasibility of introducing triple artemisinin-based combination therapy (TACT) in Vietnam to support the national malaria control and elimination plan. Methods Data were collected via 12 in-depth interviews with key stakeholders, combined with a review of policy documents. Results TACT is considered as a useful backup strategy in case future treatment failures with current artemisinin-based combination therapy (ACT) would occur. Moreover, TACT is also considered as a promising strategy to prevent the re-establishment of malaria. However, regulatory procedures and implementation timelines for TACT were expected to be lengthy. Therefore, strategies to engage national decision-makers, regulators, and suppliers should be initiated soon, stipulating the benefits of TACT deployment. In Vietnam, a procedure to apply for an import permit without registration that has previously been applied to the introduction of artesunate-pyronaridine was proposed to accelerate the introduction of TACT. Global-level support through the World Health Organization recommendations and prequalification were considered critical for supporting the introduction of TACT in Vietnam. Conclusions Appropriate approach strategies and early stakeholder engagement will be needed to accelerate the introduction of TACT in Vietnam. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 22 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Triple artemisinin-based combination therapy (TACT) Introduction strategies Drug resistance Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Triple artemisinin-based combination therapy (TACT) Introduction strategies Drug resistance Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Van Anh Thi Cao Thieu Quang Nguyen Duong Le Quyen Wouter P. C. Boon Ellen H. M. Moors Arjen M. Dondorp Freek de Haan Chanaki Amaratunga Exploring the feasibility of introducing triple artemisinin-based combination therapy in the malaria treatment policy in Vietnam |
topic_facet |
Triple artemisinin-based combination therapy (TACT) Introduction strategies Drug resistance Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background This study investigates the processes regarding changing malaria treatment policies in Vietnam. Moreover, it explores the feasibility of introducing triple artemisinin-based combination therapy (TACT) in Vietnam to support the national malaria control and elimination plan. Methods Data were collected via 12 in-depth interviews with key stakeholders, combined with a review of policy documents. Results TACT is considered as a useful backup strategy in case future treatment failures with current artemisinin-based combination therapy (ACT) would occur. Moreover, TACT is also considered as a promising strategy to prevent the re-establishment of malaria. However, regulatory procedures and implementation timelines for TACT were expected to be lengthy. Therefore, strategies to engage national decision-makers, regulators, and suppliers should be initiated soon, stipulating the benefits of TACT deployment. In Vietnam, a procedure to apply for an import permit without registration that has previously been applied to the introduction of artesunate-pyronaridine was proposed to accelerate the introduction of TACT. Global-level support through the World Health Organization recommendations and prequalification were considered critical for supporting the introduction of TACT in Vietnam. Conclusions Appropriate approach strategies and early stakeholder engagement will be needed to accelerate the introduction of TACT in Vietnam. |
format |
Article in Journal/Newspaper |
author |
Van Anh Thi Cao Thieu Quang Nguyen Duong Le Quyen Wouter P. C. Boon Ellen H. M. Moors Arjen M. Dondorp Freek de Haan Chanaki Amaratunga |
author_facet |
Van Anh Thi Cao Thieu Quang Nguyen Duong Le Quyen Wouter P. C. Boon Ellen H. M. Moors Arjen M. Dondorp Freek de Haan Chanaki Amaratunga |
author_sort |
Van Anh Thi Cao |
title |
Exploring the feasibility of introducing triple artemisinin-based combination therapy in the malaria treatment policy in Vietnam |
title_short |
Exploring the feasibility of introducing triple artemisinin-based combination therapy in the malaria treatment policy in Vietnam |
title_full |
Exploring the feasibility of introducing triple artemisinin-based combination therapy in the malaria treatment policy in Vietnam |
title_fullStr |
Exploring the feasibility of introducing triple artemisinin-based combination therapy in the malaria treatment policy in Vietnam |
title_full_unstemmed |
Exploring the feasibility of introducing triple artemisinin-based combination therapy in the malaria treatment policy in Vietnam |
title_sort |
exploring the feasibility of introducing triple artemisinin-based combination therapy in the malaria treatment policy in vietnam |
publisher |
BMC |
publishDate |
2023 |
url |
https://doi.org/10.1186/s12936-023-04763-4 https://doaj.org/article/2d66ede009644e0a8a8fb62360d26d0d |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 22, Iss 1, Pp 1-8 (2023) |
op_relation |
https://doi.org/10.1186/s12936-023-04763-4 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-023-04763-4 1475-2875 https://doaj.org/article/2d66ede009644e0a8a8fb62360d26d0d |
op_doi |
https://doi.org/10.1186/s12936-023-04763-4 |
container_title |
Malaria Journal |
container_volume |
22 |
container_issue |
1 |
_version_ |
1784265155134095360 |