Clinical assessment and pathophysiology of Bothrops venom-related acute kidney injury: a scoping review
Abstract Bothrops are one of the most common medically important snakes found in Latin America. Its venom is predominantly hemotoxic and proteolytic, which means that local lesion (edema and redness) and hemorrhagic symptoms are recurrent in envenoming by this snake. Although hemorrhage is usually t...
Published in: | Journal of Venomous Animals and Toxins including Tropical Diseases |
---|---|
Main Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
SciELO
|
Subjects: | |
Online Access: | https://doi.org/10.1590/1678-9199-jvatitd-2019-0076 https://doaj.org/article/2d0ba0fbb599407aac69445d7b39e984 |
id |
ftdoajarticles:oai:doaj.org/article:2d0ba0fbb599407aac69445d7b39e984 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:2d0ba0fbb599407aac69445d7b39e984 2023-05-15T15:16:44+02:00 Clinical assessment and pathophysiology of Bothrops venom-related acute kidney injury: a scoping review Polianna Lemos Moura Moreira Albuquerque José Hicaro Hellano Gonçalves Lima Paiva Alice Maria Costa Martins Gdayllon Cavalcante Meneses Geraldo Bezerra da Silva Júnior Nicholas Buckley Elizabeth De Francesco Daher https://doi.org/10.1590/1678-9199-jvatitd-2019-0076 https://doaj.org/article/2d0ba0fbb599407aac69445d7b39e984 EN eng SciELO http://www.scielo.br/pdf/jvatitd/v26/1678-9199-jvatitd-26-e20190076.pdf http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992020000100204&tlng=en https://doaj.org/toc/1678-9199 1678-9199 doi:10.1590/1678-9199-jvatitd-2019-0076 https://doaj.org/article/2d0ba0fbb599407aac69445d7b39e984 Journal of Venomous Animals and Toxins including Tropical Diseases Bothrops Snakebite Acute kidney injury (AKI) Envenoming Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 article ftdoajarticles https://doi.org/10.1590/1678-9199-jvatitd-2019-0076 2022-12-31T16:21:57Z Abstract Bothrops are one of the most common medically important snakes found in Latin America. Its venom is predominantly hemotoxic and proteolytic, which means that local lesion (edema and redness) and hemorrhagic symptoms are recurrent in envenoming by this snake. Although hemorrhage is usually the major cause of death, snakebite-related acute kidney injury is another potentially fatal clinical complication that may lead to chronic kidney disease. The present review highlights the main studies on Bothrops venom-related acute kidney injury, including observational, cross-sectional, case-control and cohort human studies available up to December 2019. The following descriptors were used according to Medical Subject Headings (MeSH): on Medline/Pubmed and Google Scholar “acute kidney injury” or “kidney disease” and “Bothrops”; on Lilacs and SciELO “kidney disease” or “acute kidney injury” and “Bothrops”. Newcastle-Ottawa quality assessment scale was used to appraise the quality of the cross-sectional and cohort studies included. The selection of more severe patients who looked for health care units and tertiary centers is a risk of bias. Due to the methodological heterogeneity of the studies, a critical analysis of the results was performed based on the hypothesis that the design of the included studies influences the incidence of acute kidney injury. Fifteen human studies (total participants 4624) were included according to stablished criteria. The coagulation abnormalities (hemorrhagic symptoms, abnormal fibrinogen and activated partial thromboplastin time) were associated with acute kidney injury in the most recent studies reported. The findings observed in this review provide up-to-date evidence about the acute kidney injury pathogenesis following Bothrops syndrome. Studies pointed out that coagulation abnormalities comprise the major pathway for acute kidney injury development. This review may improve patient management by primary healthcare providers, allowing earlier diagnosis and treatment of Bothrops ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Venomous Animals and Toxins including Tropical Diseases 26 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Bothrops Snakebite Acute kidney injury (AKI) Envenoming Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
spellingShingle |
Bothrops Snakebite Acute kidney injury (AKI) Envenoming Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 Polianna Lemos Moura Moreira Albuquerque José Hicaro Hellano Gonçalves Lima Paiva Alice Maria Costa Martins Gdayllon Cavalcante Meneses Geraldo Bezerra da Silva Júnior Nicholas Buckley Elizabeth De Francesco Daher Clinical assessment and pathophysiology of Bothrops venom-related acute kidney injury: a scoping review |
topic_facet |
Bothrops Snakebite Acute kidney injury (AKI) Envenoming Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
description |
Abstract Bothrops are one of the most common medically important snakes found in Latin America. Its venom is predominantly hemotoxic and proteolytic, which means that local lesion (edema and redness) and hemorrhagic symptoms are recurrent in envenoming by this snake. Although hemorrhage is usually the major cause of death, snakebite-related acute kidney injury is another potentially fatal clinical complication that may lead to chronic kidney disease. The present review highlights the main studies on Bothrops venom-related acute kidney injury, including observational, cross-sectional, case-control and cohort human studies available up to December 2019. The following descriptors were used according to Medical Subject Headings (MeSH): on Medline/Pubmed and Google Scholar “acute kidney injury” or “kidney disease” and “Bothrops”; on Lilacs and SciELO “kidney disease” or “acute kidney injury” and “Bothrops”. Newcastle-Ottawa quality assessment scale was used to appraise the quality of the cross-sectional and cohort studies included. The selection of more severe patients who looked for health care units and tertiary centers is a risk of bias. Due to the methodological heterogeneity of the studies, a critical analysis of the results was performed based on the hypothesis that the design of the included studies influences the incidence of acute kidney injury. Fifteen human studies (total participants 4624) were included according to stablished criteria. The coagulation abnormalities (hemorrhagic symptoms, abnormal fibrinogen and activated partial thromboplastin time) were associated with acute kidney injury in the most recent studies reported. The findings observed in this review provide up-to-date evidence about the acute kidney injury pathogenesis following Bothrops syndrome. Studies pointed out that coagulation abnormalities comprise the major pathway for acute kidney injury development. This review may improve patient management by primary healthcare providers, allowing earlier diagnosis and treatment of Bothrops ... |
format |
Article in Journal/Newspaper |
author |
Polianna Lemos Moura Moreira Albuquerque José Hicaro Hellano Gonçalves Lima Paiva Alice Maria Costa Martins Gdayllon Cavalcante Meneses Geraldo Bezerra da Silva Júnior Nicholas Buckley Elizabeth De Francesco Daher |
author_facet |
Polianna Lemos Moura Moreira Albuquerque José Hicaro Hellano Gonçalves Lima Paiva Alice Maria Costa Martins Gdayllon Cavalcante Meneses Geraldo Bezerra da Silva Júnior Nicholas Buckley Elizabeth De Francesco Daher |
author_sort |
Polianna Lemos Moura Moreira Albuquerque |
title |
Clinical assessment and pathophysiology of Bothrops venom-related acute kidney injury: a scoping review |
title_short |
Clinical assessment and pathophysiology of Bothrops venom-related acute kidney injury: a scoping review |
title_full |
Clinical assessment and pathophysiology of Bothrops venom-related acute kidney injury: a scoping review |
title_fullStr |
Clinical assessment and pathophysiology of Bothrops venom-related acute kidney injury: a scoping review |
title_full_unstemmed |
Clinical assessment and pathophysiology of Bothrops venom-related acute kidney injury: a scoping review |
title_sort |
clinical assessment and pathophysiology of bothrops venom-related acute kidney injury: a scoping review |
publisher |
SciELO |
url |
https://doi.org/10.1590/1678-9199-jvatitd-2019-0076 https://doaj.org/article/2d0ba0fbb599407aac69445d7b39e984 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Venomous Animals and Toxins including Tropical Diseases |
op_relation |
http://www.scielo.br/pdf/jvatitd/v26/1678-9199-jvatitd-26-e20190076.pdf http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992020000100204&tlng=en https://doaj.org/toc/1678-9199 1678-9199 doi:10.1590/1678-9199-jvatitd-2019-0076 https://doaj.org/article/2d0ba0fbb599407aac69445d7b39e984 |
op_doi |
https://doi.org/10.1590/1678-9199-jvatitd-2019-0076 |
container_title |
Journal of Venomous Animals and Toxins including Tropical Diseases |
container_volume |
26 |
_version_ |
1766347022329184256 |