Vitamin D deficiency is a potential risk factor for lipid Amphotericin B nephrotoxicity.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Daniela Ferreira, Ana Carolina de Bragança, Rildo Aparecido Volpini, Maria Heloisa Massola Shimizu, Pedro Henrique França Gois, Adriana Castello Costa Girardi, Antonio Carlos Seguro, Daniele Canale
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2019
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Napi
• Online Access: https://doi.org/10.1371/journal.pntd.0007567; https://doaj.org/article/2ce5d7f9b1974837945c64fc27108dbd

Invasive fungal infections (IFI) is a worldwide serious health problem and Amphotericin B (AmB) has been considered the drug of choice for IFI treatment. Despite its efficacy, clinical use of AmB has been associated with renal toxicity. Some lines of evidence have shown that an extemporaneous lipid...