Cost effectiveness of OptiMal ® rapid diagnostic test for malaria in remote areas of the Amazon Region, Brazil
Abstract Background In areas with limited structure in place for microscopy diagnosis, rapid diagnostic tests (RDT) have been demonstrated to be effective. Method The cost-effectiveness of the Optimal ® and thick smear microscopy was estimated and compared. Data were collected on remote areas of 12...
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ftdoajarticles:oai:doaj.org/article:2c2b93fcee144c78a78585495882aa7a 2023-05-15T15:12:51+02:00 Cost effectiveness of OptiMal ® rapid diagnostic test for malaria in remote areas of the Amazon Region, Brazil Toscano Cristiana M de Castro Gomes Almério de Oliveira Maria 2010-10-01T00:00:00Z https://doi.org/10.1186/1475-2875-9-277 https://doaj.org/article/2c2b93fcee144c78a78585495882aa7a EN eng BMC http://www.malariajournal.com/content/9/1/277 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-277 1475-2875 https://doaj.org/article/2c2b93fcee144c78a78585495882aa7a Malaria Journal, Vol 9, Iss 1, p 277 (2010) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2010 ftdoajarticles https://doi.org/10.1186/1475-2875-9-277 2022-12-30T22:50:50Z Abstract Background In areas with limited structure in place for microscopy diagnosis, rapid diagnostic tests (RDT) have been demonstrated to be effective. Method The cost-effectiveness of the Optimal ® and thick smear microscopy was estimated and compared. Data were collected on remote areas of 12 municipalities in the Brazilian Amazon. Data sources included the National Malaria Control Programme of the Ministry of Health, the National Healthcare System reimbursement table, hospitalization records, primary data collected from the municipalities, and scientific literature. The perspective was that of the Brazilian public health system, the analytical horizon was from the start of fever until the diagnostic results provided to patient and the temporal reference was that of year 2006. The results were expressed in costs per adequately diagnosed cases in 2006 U.S. dollars. Sensitivity analysis was performed considering key model parameters. Results In the case base scenario, considering 92% and 95% sensitivity for thick smear microscopy to Plasmodium falciparum and Plasmodium vivax , respectively, and 100% specificity for both species, thick smear microscopy is more costly and more effective, with an incremental cost estimated at US$549.9 per adequately diagnosed case. In sensitivity analysis, when sensitivity and specificity of microscopy for P. vivax were 0.90 and 0.98, respectively, and when its sensitivity for P. falciparum was 0.83, the RDT was more cost-effective than microscopy. Conclusion Microscopy is more cost-effective than OptiMal ® in these remote areas if high accuracy of microscopy is maintained in the field. Decision regarding use of rapid tests for diagnosis of malaria in these areas depends on current microscopy accuracy in the field. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 9 1 |
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Directory of Open Access Journals: DOAJ Articles |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Toscano Cristiana M de Castro Gomes Almério de Oliveira Maria Cost effectiveness of OptiMal ® rapid diagnostic test for malaria in remote areas of the Amazon Region, Brazil |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background In areas with limited structure in place for microscopy diagnosis, rapid diagnostic tests (RDT) have been demonstrated to be effective. Method The cost-effectiveness of the Optimal ® and thick smear microscopy was estimated and compared. Data were collected on remote areas of 12 municipalities in the Brazilian Amazon. Data sources included the National Malaria Control Programme of the Ministry of Health, the National Healthcare System reimbursement table, hospitalization records, primary data collected from the municipalities, and scientific literature. The perspective was that of the Brazilian public health system, the analytical horizon was from the start of fever until the diagnostic results provided to patient and the temporal reference was that of year 2006. The results were expressed in costs per adequately diagnosed cases in 2006 U.S. dollars. Sensitivity analysis was performed considering key model parameters. Results In the case base scenario, considering 92% and 95% sensitivity for thick smear microscopy to Plasmodium falciparum and Plasmodium vivax , respectively, and 100% specificity for both species, thick smear microscopy is more costly and more effective, with an incremental cost estimated at US$549.9 per adequately diagnosed case. In sensitivity analysis, when sensitivity and specificity of microscopy for P. vivax were 0.90 and 0.98, respectively, and when its sensitivity for P. falciparum was 0.83, the RDT was more cost-effective than microscopy. Conclusion Microscopy is more cost-effective than OptiMal ® in these remote areas if high accuracy of microscopy is maintained in the field. Decision regarding use of rapid tests for diagnosis of malaria in these areas depends on current microscopy accuracy in the field. |
format |
Article in Journal/Newspaper |
author |
Toscano Cristiana M de Castro Gomes Almério de Oliveira Maria |
author_facet |
Toscano Cristiana M de Castro Gomes Almério de Oliveira Maria |
author_sort |
Toscano Cristiana M |
title |
Cost effectiveness of OptiMal ® rapid diagnostic test for malaria in remote areas of the Amazon Region, Brazil |
title_short |
Cost effectiveness of OptiMal ® rapid diagnostic test for malaria in remote areas of the Amazon Region, Brazil |
title_full |
Cost effectiveness of OptiMal ® rapid diagnostic test for malaria in remote areas of the Amazon Region, Brazil |
title_fullStr |
Cost effectiveness of OptiMal ® rapid diagnostic test for malaria in remote areas of the Amazon Region, Brazil |
title_full_unstemmed |
Cost effectiveness of OptiMal ® rapid diagnostic test for malaria in remote areas of the Amazon Region, Brazil |
title_sort |
cost effectiveness of optimal ® rapid diagnostic test for malaria in remote areas of the amazon region, brazil |
publisher |
BMC |
publishDate |
2010 |
url |
https://doi.org/10.1186/1475-2875-9-277 https://doaj.org/article/2c2b93fcee144c78a78585495882aa7a |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 9, Iss 1, p 277 (2010) |
op_relation |
http://www.malariajournal.com/content/9/1/277 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-277 1475-2875 https://doaj.org/article/2c2b93fcee144c78a78585495882aa7a |
op_doi |
https://doi.org/10.1186/1475-2875-9-277 |
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Malaria Journal |
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9 |
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1 |
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1766343490158985216 |