The Impact of Trachomatous Trichiasis on Quality of Life: A Case Control Study.
BACKGROUND:Trachomatous trichiasis is thought to have a profound effect on quality of life (QoL), however, there is little research in this area. We measured vision and health-related QoL in a case-control study in Amhara Region, Ethiopia. METHODOLOGY/PRINCIPAL FINDINGS:We recruited 1000 adult trich...
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ftdoajarticles:oai:doaj.org/article:2c00ffd1c37c421b98476feead8992e7 2023-05-15T15:14:43+02:00 The Impact of Trachomatous Trichiasis on Quality of Life: A Case Control Study. Esmael Habtamu Tariku Wondie Sintayehu Aweke Zerihun Tadesse Mulat Zerihun Zebideru Zewudie Wondimu Gebeyehu Kelly Callahan Paul M Emerson Hannah Kuper Robin L Bailey David C W Mabey Saul N Rajak Sarah Polack Helen A Weiss Matthew J Burton 2015-11-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0004254 https://doaj.org/article/2c00ffd1c37c421b98476feead8992e7 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4657886?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004254 https://doaj.org/article/2c00ffd1c37c421b98476feead8992e7 PLoS Neglected Tropical Diseases, Vol 9, Iss 11, p e0004254 (2015) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2015 ftdoajarticles https://doi.org/10.1371/journal.pntd.0004254 2022-12-31T01:02:22Z BACKGROUND:Trachomatous trichiasis is thought to have a profound effect on quality of life (QoL), however, there is little research in this area. We measured vision and health-related QoL in a case-control study in Amhara Region, Ethiopia. METHODOLOGY/PRINCIPAL FINDINGS:We recruited 1000 adult trichiasis cases and 200 trichiasis-free controls, matched to every fifth trichiasis case on age (+/- two years), sex and location. Vision-related quality of life (VRQoL) and health-related quality of life (HRQoL) were measured using the WHO/PBD-VF20 and WHOQOL-BREF questionnaires. Comparisons were made using linear regression adjusted for age, sex and socioeconomic status. Trichiasis cases had substantially lower VRQoL than controls on all subscales (overall eyesight, visual symptom, general functioning and psychosocial, p<0.0001), even in the sub-group with normal vision (p<0.0001). Lower VRQoL scores in cases were associated with longer trichiasis duration, central corneal opacity, visual impairment and poor contrast sensitivity. Trichiasis cases had lower HRQoL in all domains (Physical-health, Psychological, Social, Environment, p<0.0001), lower overall QoL (mean, 34.5 v 64.6; p<0.0001) and overall health satisfaction (mean, 38.2 v 71.7; p<0.0001). This association persisted in a sub-group analysis of cases and controls with normal vision. Not having a marriage partner (p<0.0001), visual impairment (p = 0.0068), daily labouring (p<0.0001), presence of other health problems (p = 0.0018) and low self-rated wealth (p<0.0001) were independently associated with lower overall QoL scores in cases. Among cases, trichiasis caused 596 (59%) to feel embarrassed, 913 (91.3%) to worry they may lose their remaining eyesight and 681 (68.1%) to have sleep disturbance. CONCLUSIONS/SIGNIFICANCE:Trachomatous trichiasis substantially reduces vision and health related QoL and is disabling, even without visual impairment. Prompt trichiasis intervention is needed both to prevent vision loss and to alleviate physical ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 9 11 e0004254 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Esmael Habtamu Tariku Wondie Sintayehu Aweke Zerihun Tadesse Mulat Zerihun Zebideru Zewudie Wondimu Gebeyehu Kelly Callahan Paul M Emerson Hannah Kuper Robin L Bailey David C W Mabey Saul N Rajak Sarah Polack Helen A Weiss Matthew J Burton The Impact of Trachomatous Trichiasis on Quality of Life: A Case Control Study. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND:Trachomatous trichiasis is thought to have a profound effect on quality of life (QoL), however, there is little research in this area. We measured vision and health-related QoL in a case-control study in Amhara Region, Ethiopia. METHODOLOGY/PRINCIPAL FINDINGS:We recruited 1000 adult trichiasis cases and 200 trichiasis-free controls, matched to every fifth trichiasis case on age (+/- two years), sex and location. Vision-related quality of life (VRQoL) and health-related quality of life (HRQoL) were measured using the WHO/PBD-VF20 and WHOQOL-BREF questionnaires. Comparisons were made using linear regression adjusted for age, sex and socioeconomic status. Trichiasis cases had substantially lower VRQoL than controls on all subscales (overall eyesight, visual symptom, general functioning and psychosocial, p<0.0001), even in the sub-group with normal vision (p<0.0001). Lower VRQoL scores in cases were associated with longer trichiasis duration, central corneal opacity, visual impairment and poor contrast sensitivity. Trichiasis cases had lower HRQoL in all domains (Physical-health, Psychological, Social, Environment, p<0.0001), lower overall QoL (mean, 34.5 v 64.6; p<0.0001) and overall health satisfaction (mean, 38.2 v 71.7; p<0.0001). This association persisted in a sub-group analysis of cases and controls with normal vision. Not having a marriage partner (p<0.0001), visual impairment (p = 0.0068), daily labouring (p<0.0001), presence of other health problems (p = 0.0018) and low self-rated wealth (p<0.0001) were independently associated with lower overall QoL scores in cases. Among cases, trichiasis caused 596 (59%) to feel embarrassed, 913 (91.3%) to worry they may lose their remaining eyesight and 681 (68.1%) to have sleep disturbance. CONCLUSIONS/SIGNIFICANCE:Trachomatous trichiasis substantially reduces vision and health related QoL and is disabling, even without visual impairment. Prompt trichiasis intervention is needed both to prevent vision loss and to alleviate physical ... |
format |
Article in Journal/Newspaper |
author |
Esmael Habtamu Tariku Wondie Sintayehu Aweke Zerihun Tadesse Mulat Zerihun Zebideru Zewudie Wondimu Gebeyehu Kelly Callahan Paul M Emerson Hannah Kuper Robin L Bailey David C W Mabey Saul N Rajak Sarah Polack Helen A Weiss Matthew J Burton |
author_facet |
Esmael Habtamu Tariku Wondie Sintayehu Aweke Zerihun Tadesse Mulat Zerihun Zebideru Zewudie Wondimu Gebeyehu Kelly Callahan Paul M Emerson Hannah Kuper Robin L Bailey David C W Mabey Saul N Rajak Sarah Polack Helen A Weiss Matthew J Burton |
author_sort |
Esmael Habtamu |
title |
The Impact of Trachomatous Trichiasis on Quality of Life: A Case Control Study. |
title_short |
The Impact of Trachomatous Trichiasis on Quality of Life: A Case Control Study. |
title_full |
The Impact of Trachomatous Trichiasis on Quality of Life: A Case Control Study. |
title_fullStr |
The Impact of Trachomatous Trichiasis on Quality of Life: A Case Control Study. |
title_full_unstemmed |
The Impact of Trachomatous Trichiasis on Quality of Life: A Case Control Study. |
title_sort |
impact of trachomatous trichiasis on quality of life: a case control study. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2015 |
url |
https://doi.org/10.1371/journal.pntd.0004254 https://doaj.org/article/2c00ffd1c37c421b98476feead8992e7 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 9, Iss 11, p e0004254 (2015) |
op_relation |
http://europepmc.org/articles/PMC4657886?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004254 https://doaj.org/article/2c00ffd1c37c421b98476feead8992e7 |
op_doi |
https://doi.org/10.1371/journal.pntd.0004254 |
container_title |
PLOS Neglected Tropical Diseases |
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9 |
container_issue |
11 |
container_start_page |
e0004254 |
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