Estimating the burden of paratyphoid a in Asia and Africa.
Despite the increasing availability of typhoid vaccine in many regions, global estimates of mortality attributable to enteric fever appear stable. While both Salmonella enterica serovar Typhi (S. Typhi) and serovar Paratyphi (S. Paratyphi) cause enteric fever, limited data exist estimating the burde...
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ftdoajarticles:oai:doaj.org/article:2ad9adb3c1f44dd18b22ae4d182761ba 2023-05-15T15:16:08+02:00 Estimating the burden of paratyphoid a in Asia and Africa. Michael B Arndt Emily M Mosites Mu Tian Mohammad H Forouzanfar Ali H Mokhdad Margaret Meller Rion L Ochiai Judd L Walson 2014-06-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0002925 https://doaj.org/article/2ad9adb3c1f44dd18b22ae4d182761ba EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4046978?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002925 https://doaj.org/article/2ad9adb3c1f44dd18b22ae4d182761ba PLoS Neglected Tropical Diseases, Vol 8, Iss 6, p e2925 (2014) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2014 ftdoajarticles https://doi.org/10.1371/journal.pntd.0002925 2022-12-31T01:28:59Z Despite the increasing availability of typhoid vaccine in many regions, global estimates of mortality attributable to enteric fever appear stable. While both Salmonella enterica serovar Typhi (S. Typhi) and serovar Paratyphi (S. Paratyphi) cause enteric fever, limited data exist estimating the burden of S. Paratyphi, particularly in Asia and Africa. We performed a systematic review of both English and Chinese-language databases to estimate the regional burden of paratyphoid within Africa and Asia. Distinct from previous reviews of the topic, we have presented two separate measures of burden; both incidence and proportion of enteric fever attributable to paratyphoid. Included articles reported laboratory-confirmed Salmonella serovar classification, provided clear methods on sampling strategy, defined the age range of participants, and specified the time period of the study. A total of 64 full-text articles satisfied inclusion criteria and were included in the qualitative synthesis. Paratyphoid A was commonly identified as a cause of enteric fever throughout Asia. The highest incidence estimates in Asia came from China; four studies estimated incidence rates of over 150 cases/100,000 person-years. Paratyphoid A burden estimates from Africa were extremely limited and with the exception of Nigeria, few population or hospital-based studies from Africa reported significant Paratyphoid A burden. While significant gaps exist in the existing population-level estimates of paratyphoid burden in Asia and Africa, available data suggest that paratyphoid A is a significant cause of enteric fever in Asia. The high variability in documented incidence and proportion estimates of paratyphoid suggest considerable geospatial variability in the burden of paratyphoid fever. Additional efforts to monitor enteric fever at the population level will be necessary in order to accurately quantify the public health threat posed by S. Paratyphi A, and to improve the prevention and treatment of enteric fever. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 8 6 e2925 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Michael B Arndt Emily M Mosites Mu Tian Mohammad H Forouzanfar Ali H Mokhdad Margaret Meller Rion L Ochiai Judd L Walson Estimating the burden of paratyphoid a in Asia and Africa. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Despite the increasing availability of typhoid vaccine in many regions, global estimates of mortality attributable to enteric fever appear stable. While both Salmonella enterica serovar Typhi (S. Typhi) and serovar Paratyphi (S. Paratyphi) cause enteric fever, limited data exist estimating the burden of S. Paratyphi, particularly in Asia and Africa. We performed a systematic review of both English and Chinese-language databases to estimate the regional burden of paratyphoid within Africa and Asia. Distinct from previous reviews of the topic, we have presented two separate measures of burden; both incidence and proportion of enteric fever attributable to paratyphoid. Included articles reported laboratory-confirmed Salmonella serovar classification, provided clear methods on sampling strategy, defined the age range of participants, and specified the time period of the study. A total of 64 full-text articles satisfied inclusion criteria and were included in the qualitative synthesis. Paratyphoid A was commonly identified as a cause of enteric fever throughout Asia. The highest incidence estimates in Asia came from China; four studies estimated incidence rates of over 150 cases/100,000 person-years. Paratyphoid A burden estimates from Africa were extremely limited and with the exception of Nigeria, few population or hospital-based studies from Africa reported significant Paratyphoid A burden. While significant gaps exist in the existing population-level estimates of paratyphoid burden in Asia and Africa, available data suggest that paratyphoid A is a significant cause of enteric fever in Asia. The high variability in documented incidence and proportion estimates of paratyphoid suggest considerable geospatial variability in the burden of paratyphoid fever. Additional efforts to monitor enteric fever at the population level will be necessary in order to accurately quantify the public health threat posed by S. Paratyphi A, and to improve the prevention and treatment of enteric fever. |
format |
Article in Journal/Newspaper |
author |
Michael B Arndt Emily M Mosites Mu Tian Mohammad H Forouzanfar Ali H Mokhdad Margaret Meller Rion L Ochiai Judd L Walson |
author_facet |
Michael B Arndt Emily M Mosites Mu Tian Mohammad H Forouzanfar Ali H Mokhdad Margaret Meller Rion L Ochiai Judd L Walson |
author_sort |
Michael B Arndt |
title |
Estimating the burden of paratyphoid a in Asia and Africa. |
title_short |
Estimating the burden of paratyphoid a in Asia and Africa. |
title_full |
Estimating the burden of paratyphoid a in Asia and Africa. |
title_fullStr |
Estimating the burden of paratyphoid a in Asia and Africa. |
title_full_unstemmed |
Estimating the burden of paratyphoid a in Asia and Africa. |
title_sort |
estimating the burden of paratyphoid a in asia and africa. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2014 |
url |
https://doi.org/10.1371/journal.pntd.0002925 https://doaj.org/article/2ad9adb3c1f44dd18b22ae4d182761ba |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 8, Iss 6, p e2925 (2014) |
op_relation |
http://europepmc.org/articles/PMC4046978?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002925 https://doaj.org/article/2ad9adb3c1f44dd18b22ae4d182761ba |
op_doi |
https://doi.org/10.1371/journal.pntd.0002925 |
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PLoS Neglected Tropical Diseases |
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8 |
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6 |
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e2925 |
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