Association of Cancer Incidence and Duration of Residence in Geothermal Heating Area in Iceland: An Extended Follow-Up.
BACKGROUND:Residents of geothermal areas have higher incidence of non-Hodgkin's lymphoma, breast cancer, prostate cancer, and kidney cancers than others. These populations are exposed to chronic low-level ground gas emissions and various pollutants from geothermal water. The aim was to assess w...
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ftdoajarticles:oai:doaj.org/article:2ac8479e669e4e429256cf6ff94226fd 2023-05-15T16:52:13+02:00 Association of Cancer Incidence and Duration of Residence in Geothermal Heating Area in Iceland: An Extended Follow-Up. Adalbjorg Kristbjornsdottir Thor Aspelund Vilhjalmur Rafnsson 2016-01-01T00:00:00Z https://doi.org/10.1371/journal.pone.0155922 https://doaj.org/article/2ac8479e669e4e429256cf6ff94226fd EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4874673?pdf=render https://doaj.org/toc/1932-6203 1932-6203 doi:10.1371/journal.pone.0155922 https://doaj.org/article/2ac8479e669e4e429256cf6ff94226fd PLoS ONE, Vol 11, Iss 5, p e0155922 (2016) Medicine R Science Q article 2016 ftdoajarticles https://doi.org/10.1371/journal.pone.0155922 2023-01-08T01:33:58Z BACKGROUND:Residents of geothermal areas have higher incidence of non-Hodgkin's lymphoma, breast cancer, prostate cancer, and kidney cancers than others. These populations are exposed to chronic low-level ground gas emissions and various pollutants from geothermal water. The aim was to assess whether habitation in geothermal areas and utilisation of geothermal water is associated with risk of cancer according to duration of residence. METHODS:The cohort obtained from the census 1981 was followed to the end of 2013. Personal identifier was used in record linkage with nation-wide emigration, death, and cancer registries. The exposed population, defined by community codes, was located on young bedrock and had utilised geothermal water supply systems since 1972. Two reference populations were located by community codes on older bedrock or had not utilised geothermal water supply systems for as long a period as had the exposed population. Adjusted hazard ratio (HR), 95% confidence intervals (CI) non-stratified and stratified on cumulative years of residence were estimated in Cox-model. RESULTS:The HR for all cancer was 1.21 (95% CI 1.12-1.30) as compared with the first reference area. The HR for pancreatic cancer was 1.93 (1.22-3.06), breast cancer, 1.48 (1.23-1.80), prostate cancer 1.47 (1.22-1.77), kidney cancer 1.46 (1.03-2.05), lymphoid and haematopoietic tissue 1.54 (1.21-1.97), non-Hodgkin´s lymphoma 2.08 (1.38-3.15) and basal cell carcinoma of the skin 1.62 (1.35-1.94). Positive dose-response relationship was observed between incidence of cancers and duration of residence, and between incidence of cancer and degree of geothermal/volcanic activity in the comparison areas. CONCLUSIONS:The higher cancer incidence in geothermal areas than in reference areas is consistent with previous findings. As the dose-response relationships were positive between incidence of cancers and duration of residence, it is now more urgent than before to investigate the chemical and physical content of the geothermal water and of the ... Article in Journal/Newspaper Iceland Directory of Open Access Journals: DOAJ Articles PLOS ONE 11 5 e0155922 |
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Medicine R Science Q |
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Medicine R Science Q Adalbjorg Kristbjornsdottir Thor Aspelund Vilhjalmur Rafnsson Association of Cancer Incidence and Duration of Residence in Geothermal Heating Area in Iceland: An Extended Follow-Up. |
topic_facet |
Medicine R Science Q |
description |
BACKGROUND:Residents of geothermal areas have higher incidence of non-Hodgkin's lymphoma, breast cancer, prostate cancer, and kidney cancers than others. These populations are exposed to chronic low-level ground gas emissions and various pollutants from geothermal water. The aim was to assess whether habitation in geothermal areas and utilisation of geothermal water is associated with risk of cancer according to duration of residence. METHODS:The cohort obtained from the census 1981 was followed to the end of 2013. Personal identifier was used in record linkage with nation-wide emigration, death, and cancer registries. The exposed population, defined by community codes, was located on young bedrock and had utilised geothermal water supply systems since 1972. Two reference populations were located by community codes on older bedrock or had not utilised geothermal water supply systems for as long a period as had the exposed population. Adjusted hazard ratio (HR), 95% confidence intervals (CI) non-stratified and stratified on cumulative years of residence were estimated in Cox-model. RESULTS:The HR for all cancer was 1.21 (95% CI 1.12-1.30) as compared with the first reference area. The HR for pancreatic cancer was 1.93 (1.22-3.06), breast cancer, 1.48 (1.23-1.80), prostate cancer 1.47 (1.22-1.77), kidney cancer 1.46 (1.03-2.05), lymphoid and haematopoietic tissue 1.54 (1.21-1.97), non-Hodgkin´s lymphoma 2.08 (1.38-3.15) and basal cell carcinoma of the skin 1.62 (1.35-1.94). Positive dose-response relationship was observed between incidence of cancers and duration of residence, and between incidence of cancer and degree of geothermal/volcanic activity in the comparison areas. CONCLUSIONS:The higher cancer incidence in geothermal areas than in reference areas is consistent with previous findings. As the dose-response relationships were positive between incidence of cancers and duration of residence, it is now more urgent than before to investigate the chemical and physical content of the geothermal water and of the ... |
format |
Article in Journal/Newspaper |
author |
Adalbjorg Kristbjornsdottir Thor Aspelund Vilhjalmur Rafnsson |
author_facet |
Adalbjorg Kristbjornsdottir Thor Aspelund Vilhjalmur Rafnsson |
author_sort |
Adalbjorg Kristbjornsdottir |
title |
Association of Cancer Incidence and Duration of Residence in Geothermal Heating Area in Iceland: An Extended Follow-Up. |
title_short |
Association of Cancer Incidence and Duration of Residence in Geothermal Heating Area in Iceland: An Extended Follow-Up. |
title_full |
Association of Cancer Incidence and Duration of Residence in Geothermal Heating Area in Iceland: An Extended Follow-Up. |
title_fullStr |
Association of Cancer Incidence and Duration of Residence in Geothermal Heating Area in Iceland: An Extended Follow-Up. |
title_full_unstemmed |
Association of Cancer Incidence and Duration of Residence in Geothermal Heating Area in Iceland: An Extended Follow-Up. |
title_sort |
association of cancer incidence and duration of residence in geothermal heating area in iceland: an extended follow-up. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2016 |
url |
https://doi.org/10.1371/journal.pone.0155922 https://doaj.org/article/2ac8479e669e4e429256cf6ff94226fd |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
PLoS ONE, Vol 11, Iss 5, p e0155922 (2016) |
op_relation |
http://europepmc.org/articles/PMC4874673?pdf=render https://doaj.org/toc/1932-6203 1932-6203 doi:10.1371/journal.pone.0155922 https://doaj.org/article/2ac8479e669e4e429256cf6ff94226fd |
op_doi |
https://doi.org/10.1371/journal.pone.0155922 |
container_title |
PLOS ONE |
container_volume |
11 |
container_issue |
5 |
container_start_page |
e0155922 |
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1766042376233549824 |