Low eligibility for hepatitis B treatment in the Brazilian public health system
ABSTRACT Background: Chronic hepatitis B (CHB) affects 257 million people worldwide. However, the proportion of patients eligible for treatment in the public health system has not been established. This study describes the clinical and laboratory profiles of untreated CHB patients and estimates the...
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ftdoajarticles:oai:doaj.org/article:2a438e93a32946ba94a79405cc373953 2023-05-15T15:07:29+02:00 Low eligibility for hepatitis B treatment in the Brazilian public health system Cristiane Faria Oliveira Scarponi Marco Antônio Ferreira Pedrosa Marcos Paulo Gomes Mol Michael John Mascarenhas Hardman Dirceu Bartolomeu Greco 2022-04-01T00:00:00Z https://doi.org/10.1590/0037-8682-0297-2021 https://doaj.org/article/2a438e93a32946ba94a79405cc373953 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822022000100307&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0297-2021 https://doaj.org/article/2a438e93a32946ba94a79405cc373953 Revista da Sociedade Brasileira de Medicina Tropical, Vol 55 (2022) Hepatitis B Treatment eligibility Guideline adherence Antiviral therapy Public health Brazil Arctic medicine. Tropical medicine RC955-962 article 2022 ftdoajarticles https://doi.org/10.1590/0037-8682-0297-2021 2022-12-30T23:24:16Z ABSTRACT Background: Chronic hepatitis B (CHB) affects 257 million people worldwide. However, the proportion of patients eligible for treatment in the public health system has not been established. This study describes the clinical and laboratory profiles of untreated CHB patients and estimates the eligibility rate for antiviral therapy in accordance with the Brazilian Clinical Protocol and Therapeutic Guidelines. Methods: Records of 670 CHB patients were collected from May 2012 to September 2013 in Minas Gerais. Data from each patient were analyzed by hepatitis B virus (HBV) management. Results: 461 CHB patients were treatment-naive. Of these, 23 were HBeAg-positive, 352 were HBeAg-negative, and 14 were clinically diagnosed with cirrhosis. Periodic monitoring was performed in only three patients. However, 9.3% of untreated patients met the eligibility criteria for HBV treatment. Conclusions: Few CHB patients were active carriers and eligible candidates for antiviral therapy. This study revealed inadequate pre-treatment conduct in the Brazilian public health system, emphasizing the need for regular laboratory follow-up for patients initially not eligible for treatment. Such information may indirectly subsidize the planning and improvement of actions and services related to optimal HBV management in the public sphere. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 55 |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Hepatitis B Treatment eligibility Guideline adherence Antiviral therapy Public health Brazil Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Hepatitis B Treatment eligibility Guideline adherence Antiviral therapy Public health Brazil Arctic medicine. Tropical medicine RC955-962 Cristiane Faria Oliveira Scarponi Marco Antônio Ferreira Pedrosa Marcos Paulo Gomes Mol Michael John Mascarenhas Hardman Dirceu Bartolomeu Greco Low eligibility for hepatitis B treatment in the Brazilian public health system |
topic_facet |
Hepatitis B Treatment eligibility Guideline adherence Antiviral therapy Public health Brazil Arctic medicine. Tropical medicine RC955-962 |
description |
ABSTRACT Background: Chronic hepatitis B (CHB) affects 257 million people worldwide. However, the proportion of patients eligible for treatment in the public health system has not been established. This study describes the clinical and laboratory profiles of untreated CHB patients and estimates the eligibility rate for antiviral therapy in accordance with the Brazilian Clinical Protocol and Therapeutic Guidelines. Methods: Records of 670 CHB patients were collected from May 2012 to September 2013 in Minas Gerais. Data from each patient were analyzed by hepatitis B virus (HBV) management. Results: 461 CHB patients were treatment-naive. Of these, 23 were HBeAg-positive, 352 were HBeAg-negative, and 14 were clinically diagnosed with cirrhosis. Periodic monitoring was performed in only three patients. However, 9.3% of untreated patients met the eligibility criteria for HBV treatment. Conclusions: Few CHB patients were active carriers and eligible candidates for antiviral therapy. This study revealed inadequate pre-treatment conduct in the Brazilian public health system, emphasizing the need for regular laboratory follow-up for patients initially not eligible for treatment. Such information may indirectly subsidize the planning and improvement of actions and services related to optimal HBV management in the public sphere. |
format |
Article in Journal/Newspaper |
author |
Cristiane Faria Oliveira Scarponi Marco Antônio Ferreira Pedrosa Marcos Paulo Gomes Mol Michael John Mascarenhas Hardman Dirceu Bartolomeu Greco |
author_facet |
Cristiane Faria Oliveira Scarponi Marco Antônio Ferreira Pedrosa Marcos Paulo Gomes Mol Michael John Mascarenhas Hardman Dirceu Bartolomeu Greco |
author_sort |
Cristiane Faria Oliveira Scarponi |
title |
Low eligibility for hepatitis B treatment in the Brazilian public health system |
title_short |
Low eligibility for hepatitis B treatment in the Brazilian public health system |
title_full |
Low eligibility for hepatitis B treatment in the Brazilian public health system |
title_fullStr |
Low eligibility for hepatitis B treatment in the Brazilian public health system |
title_full_unstemmed |
Low eligibility for hepatitis B treatment in the Brazilian public health system |
title_sort |
low eligibility for hepatitis b treatment in the brazilian public health system |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2022 |
url |
https://doi.org/10.1590/0037-8682-0297-2021 https://doaj.org/article/2a438e93a32946ba94a79405cc373953 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 55 (2022) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822022000100307&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0297-2021 https://doaj.org/article/2a438e93a32946ba94a79405cc373953 |
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https://doi.org/10.1590/0037-8682-0297-2021 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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55 |
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