Neurological paradox during treatment in a non-HIV patient with pulmonary tuberculosis: A case report
Rationale: To report neurological paradox in a non-HIV patient with pulmonary tuberculosis. Patient concerns: A 26-year-old non-human immunodeficiency virus immunosuppressed female patient presented with diffused headache, diplopia, ascending paraparesis with loss of bowel and bladder control. Diagn...
| Published in: | Asian Pacific Journal of Tropical Medicine |
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| Main Authors: | , , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2022
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| Subjects: | |
| Online Access: | https://doi.org/10.4103/1995-7645.356995 https://doaj.org/article/2935265d057441cc99064e09348e99ca |
| Summary: | Rationale: To report neurological paradox in a non-HIV patient with pulmonary tuberculosis. Patient concerns: A 26-year-old non-human immunodeficiency virus immunosuppressed female patient presented with diffused headache, diplopia, ascending paraparesis with loss of bowel and bladder control. Diagnosis: Disseminated neurological paradoxical reaction developed during tuberculosis treatment in a non-human immunodeficiency virus patient. Intervention: High-dose intravenous corticosteroid was added to the anti-tuberculous drugs, followed by tapered dose of oral prednisolone in 3 months. Outcome: A favorable neurological outcome was obtained 6 months later. Lessons: Neurological paradoxical reaction cannot be overlooked among the tuberculosis-treated cases who present with newly emerged neurological disorders. |
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