Avaliação de antígenos de Cysticercus cellulosae no imunodiagnóstico da cisticercose humana pela hemaglutinação indireta Evaluation of antigens from Cysticercus cellulosae for immunodiagnosis of human cysticercosis by hemagglutination test

• Main Authors: E. Nascimento, W. Mayrink
• Format: Article in Journal/Newspaper
• Language: English
• Published: Universidade de São Paulo (USP) 1984
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic
• Online Access: https://doaj.org/article/291abef2b40443fd85d2c72d700c573b

Os Autores avaliaram os antígenos de Cysticercus cellulosae para o imunodiagnóstico da cistieercose humana pela reação de hemaglutinação indireta. Observaram que os antígenos de escólex (ES) e ES pico II são mais específicos que os antígenos de C. cellulosae total (CC), líquido vesicular e de membrana (ME). Usando soros de pacientes com cistieercose comprovada parasitologicamente, obtiveram uma sensibilidade de 0,80 para o ES, 0,84 para o ES II e especificidade 1,0, quando os soros foram usados na diluição 1:8 para o antígeno ES e 1:16 para o antígeno ES II. The Authors evaluated the use of antigens from Cysticercus cellulosae in the immunodiagnosis of human cysticercosis by haemagglutination test. The extract prepared from the es-colex and its chromatographic peak II were more specific than those from whole larvae, vesicular liquid and membrane antigens. Using sera from patients with parasitologically proven cysticercosis, positive reactions were obtained with a sensitivity index of 0.80 for escolex antigen and 0.84 escolex peak II antigen. Specificity of 1.0 was obtained for sera diluted at 1:8 for ES and 1:16 for ES II antigens.