The 'hidden' burden of malaria: cognitive impairment following infection
Abstract Background The burden of post-malaria cognitive impairment is often overlooked. Given the large number of infections occurring worldwide, the magnitude of the problem is likely to be substantial. The objectives of this paper are; (i) to assess the evidence on post malarial cognitive impairm...
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ftdoajarticles:oai:doaj.org/article:276e23781a6e4ffd936ae2c5037e73b4 2023-05-15T15:08:36+02:00 The 'hidden' burden of malaria: cognitive impairment following infection Rodrigo Chaturaka Fernando Sumadhya D Rajapakse Senaka 2010-12-01T00:00:00Z https://doi.org/10.1186/1475-2875-9-366 https://doaj.org/article/276e23781a6e4ffd936ae2c5037e73b4 EN eng BMC http://www.malariajournal.com/content/9/1/366 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-366 1475-2875 https://doaj.org/article/276e23781a6e4ffd936ae2c5037e73b4 Malaria Journal, Vol 9, Iss 1, p 366 (2010) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2010 ftdoajarticles https://doi.org/10.1186/1475-2875-9-366 2022-12-31T04:21:44Z Abstract Background The burden of post-malaria cognitive impairment is often overlooked. Given the large number of infections occurring worldwide, the magnitude of the problem is likely to be substantial. The objectives of this paper are; (i) to assess the evidence on post malarial cognitive impairment or impact on school education; (ii) to assess the possible positive impact of malaria drug prophylaxis on cognition; and (iii) to suggest recommendations on minimizing the burden of post-malarial cognitive impairment Methods PUBMED and SCOPUS were searched for all articles with the key word 'Malaria' in the title field and 'cognitive impairment' in any field. Google Scholar was searched for the same keywords anywhere in the article. The search was restricted to articles published in English within the last 15 years (1995-2010). After filtering of abstracts from the initial search, 44 papers had research evidence on this topic. Results & Discussion Cognitive abilities and school performance were shown to be impaired in sub-groups of patients (with either cerebral malaria or uncomplicated malaria) when compared with healthy controls. Studies comparing cognitive functions before and after treatment for acute malarial illness continued to show significantly impaired school performance and cognitive abilities even after recovery. Malaria prophylaxis was shown to improve cognitive function and school performance in clinical trials when compared to placebo groups. The implications of these findings are discussed. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 9 1 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Rodrigo Chaturaka Fernando Sumadhya D Rajapakse Senaka The 'hidden' burden of malaria: cognitive impairment following infection |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background The burden of post-malaria cognitive impairment is often overlooked. Given the large number of infections occurring worldwide, the magnitude of the problem is likely to be substantial. The objectives of this paper are; (i) to assess the evidence on post malarial cognitive impairment or impact on school education; (ii) to assess the possible positive impact of malaria drug prophylaxis on cognition; and (iii) to suggest recommendations on minimizing the burden of post-malarial cognitive impairment Methods PUBMED and SCOPUS were searched for all articles with the key word 'Malaria' in the title field and 'cognitive impairment' in any field. Google Scholar was searched for the same keywords anywhere in the article. The search was restricted to articles published in English within the last 15 years (1995-2010). After filtering of abstracts from the initial search, 44 papers had research evidence on this topic. Results & Discussion Cognitive abilities and school performance were shown to be impaired in sub-groups of patients (with either cerebral malaria or uncomplicated malaria) when compared with healthy controls. Studies comparing cognitive functions before and after treatment for acute malarial illness continued to show significantly impaired school performance and cognitive abilities even after recovery. Malaria prophylaxis was shown to improve cognitive function and school performance in clinical trials when compared to placebo groups. The implications of these findings are discussed. |
format |
Article in Journal/Newspaper |
author |
Rodrigo Chaturaka Fernando Sumadhya D Rajapakse Senaka |
author_facet |
Rodrigo Chaturaka Fernando Sumadhya D Rajapakse Senaka |
author_sort |
Rodrigo Chaturaka |
title |
The 'hidden' burden of malaria: cognitive impairment following infection |
title_short |
The 'hidden' burden of malaria: cognitive impairment following infection |
title_full |
The 'hidden' burden of malaria: cognitive impairment following infection |
title_fullStr |
The 'hidden' burden of malaria: cognitive impairment following infection |
title_full_unstemmed |
The 'hidden' burden of malaria: cognitive impairment following infection |
title_sort |
'hidden' burden of malaria: cognitive impairment following infection |
publisher |
BMC |
publishDate |
2010 |
url |
https://doi.org/10.1186/1475-2875-9-366 https://doaj.org/article/276e23781a6e4ffd936ae2c5037e73b4 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 9, Iss 1, p 366 (2010) |
op_relation |
http://www.malariajournal.com/content/9/1/366 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-366 1475-2875 https://doaj.org/article/276e23781a6e4ffd936ae2c5037e73b4 |
op_doi |
https://doi.org/10.1186/1475-2875-9-366 |
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Malaria Journal |
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9 |
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1 |
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1766339933912432640 |