Demonstration of the Coexistence of Duplicated LH Receptors in Teleosts, and Their Origin in Ancestral Actinopterygians.

• Published in: PLOS ONE
• Main Authors: Gersende Maugars, Sylvie Dufour
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2015
• Subjects: Medicine; R; Science; Q; Gar’; European eel
• Online Access: https://doi.org/10.1371/journal.pone.0135184; https://doaj.org/article/27033a43cb7a49559fdf8e988b6e38c4

Pituitary gonadotropins, FSH and LH, control gonad activity in vertebrates, via binding to their respective receptors, FSHR and LHR, members of GPCR superfamily. Until recently, it was accepted that gnathostomes possess a single FSHR and a single LHR, encoded by fshr and lhcgr genes. We reinvestigat...