The disease burden of human cystic echinococcosis based on HDRs from 2001 to 2014 in Italy.
Cystic echinococcosis (CE) is an important neglected zoonotic parasitic infection belonging to the subgroup of seven Neglected Zoonotic Disease (NZDs) included in the World Health Organization's official list of 18 Neglected Tropical Diseases (NTDs). CE causes serious global human health concer...
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ftdoajarticles:oai:doaj.org/article:26adf060ff924a4185e6b09a3efafd24 2023-05-15T15:18:37+02:00 The disease burden of human cystic echinococcosis based on HDRs from 2001 to 2014 in Italy. Toni Piseddu Diego Brundu Giovanni Stegel Federica Loi Sandro Rolesu Gabriella Masu Salvatore Ledda Giovanna Masala 2017-07-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0005771 https://doaj.org/article/26adf060ff924a4185e6b09a3efafd24 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC5546721?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0005771 https://doaj.org/article/26adf060ff924a4185e6b09a3efafd24 PLoS Neglected Tropical Diseases, Vol 11, Iss 7, p e0005771 (2017) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2017 ftdoajarticles https://doi.org/10.1371/journal.pntd.0005771 2022-12-31T10:36:11Z Cystic echinococcosis (CE) is an important neglected zoonotic parasitic infection belonging to the subgroup of seven Neglected Zoonotic Disease (NZDs) included in the World Health Organization's official list of 18 Neglected Tropical Diseases (NTDs). CE causes serious global human health concerns and leads to significant economic losses arising from the costs of medical treatment, morbidity, life impairments and fatality rates in human cases. Moreover, CE is endemic in several Italian Regions. The aim of this study is to perform a detailed analysis of the economic burden of hospitalization and treatment costs and to estimate the Disability Adjusted Life Years (DALYs) of CE in Italy.In the period from 2001 to 2014, the direct costs of 21,050 Hospital Discharge Records (HDRs) belonging to 12,619 patients with at least one CE-related diagnosis codes were analyzed in order to quantify the economic burden of CE. CE cases average per annum are 901 (min-max = 480-1,583). Direct costs include expenses for hospitalizations, medical and surgical treatment incurred by public and private hospitals and were computed on an individual basis according to Italian Health Ministry legislation. Moreover, we estimated the DALYs for each patient. The Italian financial burden of CE is around € 53 million; the national average economic burden per annum is around € 4 million; the DALYs of the population from 2001 to 2014 are 223.35 annually and 5.26 DALYs per 105 inhabitants.In Italy, human CE is responsible for significant economic losses in the public health sector. In humans, costs associated with CE have been shown to have a great impact on affected individuals, their families and the community as a whole. This study could be used as a tool to prioritize and make decisions with regard to a surveillance system for this largely preventable yet neglected disease. It demonstrates the need of implementing a CE control program aimed at preventing the considerable economic and social losses it causes in high incidence areas. Article in Journal/Newspaper Arctic Human health Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 11 7 e0005771 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Toni Piseddu Diego Brundu Giovanni Stegel Federica Loi Sandro Rolesu Gabriella Masu Salvatore Ledda Giovanna Masala The disease burden of human cystic echinococcosis based on HDRs from 2001 to 2014 in Italy. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Cystic echinococcosis (CE) is an important neglected zoonotic parasitic infection belonging to the subgroup of seven Neglected Zoonotic Disease (NZDs) included in the World Health Organization's official list of 18 Neglected Tropical Diseases (NTDs). CE causes serious global human health concerns and leads to significant economic losses arising from the costs of medical treatment, morbidity, life impairments and fatality rates in human cases. Moreover, CE is endemic in several Italian Regions. The aim of this study is to perform a detailed analysis of the economic burden of hospitalization and treatment costs and to estimate the Disability Adjusted Life Years (DALYs) of CE in Italy.In the period from 2001 to 2014, the direct costs of 21,050 Hospital Discharge Records (HDRs) belonging to 12,619 patients with at least one CE-related diagnosis codes were analyzed in order to quantify the economic burden of CE. CE cases average per annum are 901 (min-max = 480-1,583). Direct costs include expenses for hospitalizations, medical and surgical treatment incurred by public and private hospitals and were computed on an individual basis according to Italian Health Ministry legislation. Moreover, we estimated the DALYs for each patient. The Italian financial burden of CE is around € 53 million; the national average economic burden per annum is around € 4 million; the DALYs of the population from 2001 to 2014 are 223.35 annually and 5.26 DALYs per 105 inhabitants.In Italy, human CE is responsible for significant economic losses in the public health sector. In humans, costs associated with CE have been shown to have a great impact on affected individuals, their families and the community as a whole. This study could be used as a tool to prioritize and make decisions with regard to a surveillance system for this largely preventable yet neglected disease. It demonstrates the need of implementing a CE control program aimed at preventing the considerable economic and social losses it causes in high incidence areas. |
format |
Article in Journal/Newspaper |
author |
Toni Piseddu Diego Brundu Giovanni Stegel Federica Loi Sandro Rolesu Gabriella Masu Salvatore Ledda Giovanna Masala |
author_facet |
Toni Piseddu Diego Brundu Giovanni Stegel Federica Loi Sandro Rolesu Gabriella Masu Salvatore Ledda Giovanna Masala |
author_sort |
Toni Piseddu |
title |
The disease burden of human cystic echinococcosis based on HDRs from 2001 to 2014 in Italy. |
title_short |
The disease burden of human cystic echinococcosis based on HDRs from 2001 to 2014 in Italy. |
title_full |
The disease burden of human cystic echinococcosis based on HDRs from 2001 to 2014 in Italy. |
title_fullStr |
The disease burden of human cystic echinococcosis based on HDRs from 2001 to 2014 in Italy. |
title_full_unstemmed |
The disease burden of human cystic echinococcosis based on HDRs from 2001 to 2014 in Italy. |
title_sort |
disease burden of human cystic echinococcosis based on hdrs from 2001 to 2014 in italy. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2017 |
url |
https://doi.org/10.1371/journal.pntd.0005771 https://doaj.org/article/26adf060ff924a4185e6b09a3efafd24 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Human health |
genre_facet |
Arctic Human health |
op_source |
PLoS Neglected Tropical Diseases, Vol 11, Iss 7, p e0005771 (2017) |
op_relation |
http://europepmc.org/articles/PMC5546721?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0005771 https://doaj.org/article/26adf060ff924a4185e6b09a3efafd24 |
op_doi |
https://doi.org/10.1371/journal.pntd.0005771 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
11 |
container_issue |
7 |
container_start_page |
e0005771 |
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1766348817208180736 |