Characteristics of pulmonary tuberculosis in HIV seropositive and seronegative patients in a Northeastern region of Brazil
The aim of this study was to analyse the clinical, epidemiological and bacteriological features present in 60 pulmonary tuberculosis patients who were also infected with human immunodeficiency virus (HIV) and to compare these with 120 TB patients who were not infected with HIV. The patients with pul...
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Sociedade Brasileira de Medicina Tropical (SBMT)
2004
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ftdoajarticles:oai:doaj.org/article:26a2f9ee53f14511a4a85de6b07ba1ca 2023-05-15T15:06:29+02:00 Characteristics of pulmonary tuberculosis in HIV seropositive and seronegative patients in a Northeastern region of Brazil Liberato Isabella Ramos de Oliveira Albuquerque Maria de Fatima P. Militão de Campelo Antônio Roberto Leite Melo Heloísa Ramos Lacerda de 2004-01-01T00:00:00Z https://doaj.org/article/26a2f9ee53f14511a4a85de6b07ba1ca EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822004000100012 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/26a2f9ee53f14511a4a85de6b07ba1ca Revista da Sociedade Brasileira de Medicina Tropical, Vol 37, Iss 1, Pp 46-50 (2004) Tuberculosis Tuberculosis/HIV co-infection Arctic medicine. Tropical medicine RC955-962 article 2004 ftdoajarticles 2022-12-30T21:38:14Z The aim of this study was to analyse the clinical, epidemiological and bacteriological features present in 60 pulmonary tuberculosis patients who were also infected with human immunodeficiency virus (HIV) and to compare these with 120 TB patients who were not infected with HIV. The patients with pulmonary tuberculosis and HIV coinfection were mostly male (p = 0.001), showed a higher frequency of weight loss >10 kilos (p <0.001), had a higher rate of non-reaction result to the tuberculin skin test (p <0.001), a higher frequency of negative sputum smear examination for acid-fast bacilli (p = 0.001) and negative sputum culture for Mycobacterium tuberculosis (p = 0.001). Treatment failure was more common in those who were HIV positive (p <0.000). No higher frequency of resistance to antituberculosis drugs was found to be associated with TB/HIV coinfection (p = 0.407). Association between extrapulmonary and pulmonary tuberculosis was more frequent in those seropositive to HIV than those without HIV virus, 30% and 1.6% respectively. These findings showed a predominance of atypical clinical laboratory features in co-infected patients, and suggest that health care personnel should consider the possibility this diagnosis. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Tuberculosis Tuberculosis/HIV co-infection Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Tuberculosis Tuberculosis/HIV co-infection Arctic medicine. Tropical medicine RC955-962 Liberato Isabella Ramos de Oliveira Albuquerque Maria de Fatima P. Militão de Campelo Antônio Roberto Leite Melo Heloísa Ramos Lacerda de Characteristics of pulmonary tuberculosis in HIV seropositive and seronegative patients in a Northeastern region of Brazil |
topic_facet |
Tuberculosis Tuberculosis/HIV co-infection Arctic medicine. Tropical medicine RC955-962 |
description |
The aim of this study was to analyse the clinical, epidemiological and bacteriological features present in 60 pulmonary tuberculosis patients who were also infected with human immunodeficiency virus (HIV) and to compare these with 120 TB patients who were not infected with HIV. The patients with pulmonary tuberculosis and HIV coinfection were mostly male (p = 0.001), showed a higher frequency of weight loss >10 kilos (p <0.001), had a higher rate of non-reaction result to the tuberculin skin test (p <0.001), a higher frequency of negative sputum smear examination for acid-fast bacilli (p = 0.001) and negative sputum culture for Mycobacterium tuberculosis (p = 0.001). Treatment failure was more common in those who were HIV positive (p <0.000). No higher frequency of resistance to antituberculosis drugs was found to be associated with TB/HIV coinfection (p = 0.407). Association between extrapulmonary and pulmonary tuberculosis was more frequent in those seropositive to HIV than those without HIV virus, 30% and 1.6% respectively. These findings showed a predominance of atypical clinical laboratory features in co-infected patients, and suggest that health care personnel should consider the possibility this diagnosis. |
format |
Article in Journal/Newspaper |
author |
Liberato Isabella Ramos de Oliveira Albuquerque Maria de Fatima P. Militão de Campelo Antônio Roberto Leite Melo Heloísa Ramos Lacerda de |
author_facet |
Liberato Isabella Ramos de Oliveira Albuquerque Maria de Fatima P. Militão de Campelo Antônio Roberto Leite Melo Heloísa Ramos Lacerda de |
author_sort |
Liberato Isabella Ramos de Oliveira |
title |
Characteristics of pulmonary tuberculosis in HIV seropositive and seronegative patients in a Northeastern region of Brazil |
title_short |
Characteristics of pulmonary tuberculosis in HIV seropositive and seronegative patients in a Northeastern region of Brazil |
title_full |
Characteristics of pulmonary tuberculosis in HIV seropositive and seronegative patients in a Northeastern region of Brazil |
title_fullStr |
Characteristics of pulmonary tuberculosis in HIV seropositive and seronegative patients in a Northeastern region of Brazil |
title_full_unstemmed |
Characteristics of pulmonary tuberculosis in HIV seropositive and seronegative patients in a Northeastern region of Brazil |
title_sort |
characteristics of pulmonary tuberculosis in hiv seropositive and seronegative patients in a northeastern region of brazil |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2004 |
url |
https://doaj.org/article/26a2f9ee53f14511a4a85de6b07ba1ca |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 37, Iss 1, Pp 46-50 (2004) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822004000100012 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/26a2f9ee53f14511a4a85de6b07ba1ca |
_version_ |
1766338084688887808 |