A Piece of the Puzzle—Possible Mechanisms for Why Low Dietary EPA and DHA Cause Hepatic Lipid Accumulation in Atlantic Salmon ( Salmo salar )

• Published in: Metabolites
• Main Authors: Bjørg Kristine Hundal, Esmail Lutfi, Trygve Sigholt, Grethe Rosenlund, Nina Sylvia Liland, Brett Glencross, Nini Hedberg Sissener
• Format: Article in Journal/Newspaper
• Language: English
• Published: MDPI AG 2022
• Subjects: lipid metabolism; EPA; DHA; robustness; Atlantic salmon; metabolomics; Microbiology; QR1-502; Slaughter; Salmo salar
• Online Access: https://doi.org/10.3390/metabo12020159; https://doaj.org/article/269a05c6ee064fa397bfb65aa7c04ace

The present study aimed at elucidating the effects of graded levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on the hepatic metabolic health of Atlantic salmon reared in sea cages. Diets containing 10, 13, 16 and 35 g/kg EPA + DHA (designated diets 1.0, 1.3, 1.6 and 3.5, respect...