Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis)
A dengue fever case is described in a 58-year-old male patient with febrile illness and thrombocytopenia complicated by neurological involvement characterized by transverse myelitis followed by weakness of both legs and flaccid paralysis. Muscle strength was much diminished and bilateral areflexia w...
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Sociedade Brasileira de Medicina Tropical (SBMT)
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ftdoajarticles:oai:doaj.org/article:25f2b0c33e574d2e8b969515cf202493 2023-05-15T15:03:19+02:00 Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis) Leão Raimundo N.Q. Oikawa Teichi Rosa Elizabeth S.T. Yamaki José T. Rodrigues Sueli G. Vasconcelos Helena B. Sousa Maria R.S. Tsukimata Jaime K. Azevedo Raimunda S.S. Vasconcelos Pedro F.C. 2002-01-01T00:00:00Z https://doaj.org/article/25f2b0c33e574d2e8b969515cf202493 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000400018 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/25f2b0c33e574d2e8b969515cf202493 Revista da Sociedade Brasileira de Medicina Tropical, Vol 35, Iss 4, Pp 401-404 (2002) Dengue fever Transverse myelitis Dengue 2 Virus isolation RT-PCR Arctic medicine. Tropical medicine RC955-962 article 2002 ftdoajarticles 2022-12-30T23:17:38Z A dengue fever case is described in a 58-year-old male patient with febrile illness and thrombocytopenia complicated by neurological involvement characterized by transverse myelitis followed by weakness of both legs and flaccid paralysis. Muscle strength was much diminished and bilateral areflexia was observed. Dengue 2 (DEN-2) virus was isolated and the patient sero-converted by hemagglutination-inhibition and IgM-ELISA tests. The RT-PCR test was positive to DEN-2 in acute phase serum and culture supernatant, but negative in the cerebrospinal fluid. After three weeks of hospitalization the patient was discharged. No other infectious agent was detected in the blood and cerebrospinal fluid samples. The patient had full recovery from paralysis six months after the onset of DEN-2 infection. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
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Dengue fever Transverse myelitis Dengue 2 Virus isolation RT-PCR Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Dengue fever Transverse myelitis Dengue 2 Virus isolation RT-PCR Arctic medicine. Tropical medicine RC955-962 Leão Raimundo N.Q. Oikawa Teichi Rosa Elizabeth S.T. Yamaki José T. Rodrigues Sueli G. Vasconcelos Helena B. Sousa Maria R.S. Tsukimata Jaime K. Azevedo Raimunda S.S. Vasconcelos Pedro F.C. Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis) |
topic_facet |
Dengue fever Transverse myelitis Dengue 2 Virus isolation RT-PCR Arctic medicine. Tropical medicine RC955-962 |
description |
A dengue fever case is described in a 58-year-old male patient with febrile illness and thrombocytopenia complicated by neurological involvement characterized by transverse myelitis followed by weakness of both legs and flaccid paralysis. Muscle strength was much diminished and bilateral areflexia was observed. Dengue 2 (DEN-2) virus was isolated and the patient sero-converted by hemagglutination-inhibition and IgM-ELISA tests. The RT-PCR test was positive to DEN-2 in acute phase serum and culture supernatant, but negative in the cerebrospinal fluid. After three weeks of hospitalization the patient was discharged. No other infectious agent was detected in the blood and cerebrospinal fluid samples. The patient had full recovery from paralysis six months after the onset of DEN-2 infection. |
format |
Article in Journal/Newspaper |
author |
Leão Raimundo N.Q. Oikawa Teichi Rosa Elizabeth S.T. Yamaki José T. Rodrigues Sueli G. Vasconcelos Helena B. Sousa Maria R.S. Tsukimata Jaime K. Azevedo Raimunda S.S. Vasconcelos Pedro F.C. |
author_facet |
Leão Raimundo N.Q. Oikawa Teichi Rosa Elizabeth S.T. Yamaki José T. Rodrigues Sueli G. Vasconcelos Helena B. Sousa Maria R.S. Tsukimata Jaime K. Azevedo Raimunda S.S. Vasconcelos Pedro F.C. |
author_sort |
Leão Raimundo N.Q. |
title |
Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis) |
title_short |
Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis) |
title_full |
Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis) |
title_fullStr |
Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis) |
title_full_unstemmed |
Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis) |
title_sort |
isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis) |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2002 |
url |
https://doaj.org/article/25f2b0c33e574d2e8b969515cf202493 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 35, Iss 4, Pp 401-404 (2002) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000400018 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/25f2b0c33e574d2e8b969515cf202493 |
_version_ |
1766335189080866816 |