Treatment of chronic hepatitis C in non-responsive patients with pegylated interferon associated with ribavirin and thalidomide: report of six cases of total remission Tratamento de hepatite C crônica em pacientes não respondedores, com a associação interferon peguilado, ribavirina e talidomida: Relato de seis casos
Hepatitis C virus (HCV) infection is an important public health issue worldwide. It is estimated that over 170 million people are infected with the virus. The present study reports six cases in which patients did not respond to combination therapy with pegylated interferon and ribavirin. However, af...
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ftdoajarticles:oai:doaj.org/article:25d4b347348d49d0b4f1105e3f035051 2024-09-09T19:25:50+00:00 Treatment of chronic hepatitis C in non-responsive patients with pegylated interferon associated with ribavirin and thalidomide: report of six cases of total remission Tratamento de hepatite C crônica em pacientes não respondedores, com a associação interferon peguilado, ribavirina e talidomida: Relato de seis casos Marcos Montani Caseiro 2006-04-01T00:00:00Z https://doi.org/10.1590/S0036-46652006000200011 https://doaj.org/article/25d4b347348d49d0b4f1105e3f035051 EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652006000200011 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46652006000200011 0036-4665 1678-9946 https://doaj.org/article/25d4b347348d49d0b4f1105e3f035051 Revista do Instituto de Medicina Tropical de São Paulo, Vol 48, Iss 2, Pp 109-112 (2006) Hepatitis C Thalidomide Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2006 ftdoajarticles https://doi.org/10.1590/S0036-46652006000200011 2024-08-05T17:49:30Z Hepatitis C virus (HCV) infection is an important public health issue worldwide. It is estimated that over 170 million people are infected with the virus. The present study reports six cases in which patients did not respond to combination therapy with pegylated interferon and ribavirin. However, after the addition of thalidomide to the therapy, the patients presented negative RNA PCR. The use of thalidomide combined with pegylated interferon and ribavirin for the treatment of hepatitis C is described here for the first time in the related literature. A infecção pelo vírus da Hepatite C (HCV) representa um importante problema de saúde pública no mundo, estima-se que mais de 170 milhões de pessoas estejam infectadas. Relatamos o encontro de 6 pacientes não respondedores à associação de Interferon Peguilado e Ribavirina que negativaram seu PCRRNA após a associação com talidomida. Trata-se do primeiro relato desta associação no tratamento da hepatite C encontrado na literatura. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 48 2 109 112 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
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Hepatitis C Thalidomide Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Hepatitis C Thalidomide Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Marcos Montani Caseiro Treatment of chronic hepatitis C in non-responsive patients with pegylated interferon associated with ribavirin and thalidomide: report of six cases of total remission Tratamento de hepatite C crônica em pacientes não respondedores, com a associação interferon peguilado, ribavirina e talidomida: Relato de seis casos |
topic_facet |
Hepatitis C Thalidomide Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Hepatitis C virus (HCV) infection is an important public health issue worldwide. It is estimated that over 170 million people are infected with the virus. The present study reports six cases in which patients did not respond to combination therapy with pegylated interferon and ribavirin. However, after the addition of thalidomide to the therapy, the patients presented negative RNA PCR. The use of thalidomide combined with pegylated interferon and ribavirin for the treatment of hepatitis C is described here for the first time in the related literature. A infecção pelo vírus da Hepatite C (HCV) representa um importante problema de saúde pública no mundo, estima-se que mais de 170 milhões de pessoas estejam infectadas. Relatamos o encontro de 6 pacientes não respondedores à associação de Interferon Peguilado e Ribavirina que negativaram seu PCRRNA após a associação com talidomida. Trata-se do primeiro relato desta associação no tratamento da hepatite C encontrado na literatura. |
format |
Article in Journal/Newspaper |
author |
Marcos Montani Caseiro |
author_facet |
Marcos Montani Caseiro |
author_sort |
Marcos Montani Caseiro |
title |
Treatment of chronic hepatitis C in non-responsive patients with pegylated interferon associated with ribavirin and thalidomide: report of six cases of total remission Tratamento de hepatite C crônica em pacientes não respondedores, com a associação interferon peguilado, ribavirina e talidomida: Relato de seis casos |
title_short |
Treatment of chronic hepatitis C in non-responsive patients with pegylated interferon associated with ribavirin and thalidomide: report of six cases of total remission Tratamento de hepatite C crônica em pacientes não respondedores, com a associação interferon peguilado, ribavirina e talidomida: Relato de seis casos |
title_full |
Treatment of chronic hepatitis C in non-responsive patients with pegylated interferon associated with ribavirin and thalidomide: report of six cases of total remission Tratamento de hepatite C crônica em pacientes não respondedores, com a associação interferon peguilado, ribavirina e talidomida: Relato de seis casos |
title_fullStr |
Treatment of chronic hepatitis C in non-responsive patients with pegylated interferon associated with ribavirin and thalidomide: report of six cases of total remission Tratamento de hepatite C crônica em pacientes não respondedores, com a associação interferon peguilado, ribavirina e talidomida: Relato de seis casos |
title_full_unstemmed |
Treatment of chronic hepatitis C in non-responsive patients with pegylated interferon associated with ribavirin and thalidomide: report of six cases of total remission Tratamento de hepatite C crônica em pacientes não respondedores, com a associação interferon peguilado, ribavirina e talidomida: Relato de seis casos |
title_sort |
treatment of chronic hepatitis c in non-responsive patients with pegylated interferon associated with ribavirin and thalidomide: report of six cases of total remission tratamento de hepatite c crônica em pacientes não respondedores, com a associação interferon peguilado, ribavirina e talidomida: relato de seis casos |
publisher |
Universidade de São Paulo (USP) |
publishDate |
2006 |
url |
https://doi.org/10.1590/S0036-46652006000200011 https://doaj.org/article/25d4b347348d49d0b4f1105e3f035051 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 48, Iss 2, Pp 109-112 (2006) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652006000200011 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46652006000200011 0036-4665 1678-9946 https://doaj.org/article/25d4b347348d49d0b4f1105e3f035051 |
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https://doi.org/10.1590/S0036-46652006000200011 |
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Revista do Instituto de Medicina Tropical de São Paulo |
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48 |
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112 |
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