Uneventful benznidazole treatment of acute Chagas disease during pregnancy: a case report

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Valeria Rita Corrêa, Fernanda Gama Barbosa, Claudimar Américo de Melo Junior, Luis Fernando D'Albuquerque e Castro, Heitor Franco de Andrade Junior, Nanci Nascimento
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2014
• Subjects: Acute Chagas disease; Benznidazole; Pregnancy; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.1590/0037-8682-0250-2013; https://doaj.org/article/256c895bc8584b59a8c2de8fefb3cac1

This report describes the case of a patient with acute Chagas disease in Tocantins, Brazil, who was unaware of her pregnancy during benznidazole treatment. She presented with impaired cardiac function during the acute phase (pericarditis and incomplete right bundle-branch block) that resolved favorably after benznidazole therapy. Serological results also became negative, as determined by hemagglutination assays, enzyme-linked immunosorbent assays, and immunofluorescence assays. The child was born without sequelae and showed no evidence of congenital Trypanosoma cruzi infection at birth or 24 days later.