High prevalence of HTLV-1 and 2 viruses in pregnant women in São Luis, state of Maranhão, Brazil
INTRODUCTION: Human T cell lymphotropic virus type 1 (HTLV-1) is endemic in the Caribbean, Japan, South America and regions of Africa. HTLV-2 is present in Native American populations and associated with IV drug use in Europe and North America. In Brazil, it is estimated that 1.5 million people are...
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ftdoajarticles:oai:doaj.org/article:24ff0dec16584d51baa69864c2986650 2023-05-15T15:13:08+02:00 High prevalence of HTLV-1 and 2 viruses in pregnant women in São Luis, state of Maranhão, Brazil Verônica Guimarães de Souza Marina Lobato Martins Anna Bárbara de Freitas Carneiro-Proietti José Nélio Januário Roberto Vagner Puglia Ladeira Camila Moreira Serra Silva Claudyene Pires Samea Cristina Gomes Christiane de Souza Martins Elba Gomide Mochel 2012-04-01T00:00:00Z https://doi.org/10.1590/S0037-86822012000200004 https://doaj.org/article/24ff0dec16584d51baa69864c2986650 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000200004&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/S0037-86822012000200004 https://doaj.org/article/24ff0dec16584d51baa69864c2986650 Revista da Sociedade Brasileira de Medicina Tropical, Vol 45, Iss 2, Pp 159-162 (2012) HTLV-1/2 Gravidez Prevalência Maranhão Brasil Arctic medicine. Tropical medicine RC955-962 article 2012 ftdoajarticles https://doi.org/10.1590/S0037-86822012000200004 2022-12-30T21:38:12Z INTRODUCTION: Human T cell lymphotropic virus type 1 (HTLV-1) is endemic in the Caribbean, Japan, South America and regions of Africa. HTLV-2 is present in Native American populations and associated with IV drug use in Europe and North America. In Brazil, it is estimated that 1.5 million people are infected with HTLV-1/2. The study objective was to determine HTLV-1/2 prevalence in pregnant women in the prenatal care from three public services in São Luis, State of Maranhão, Brazil, and to counsel seropositive women to reduce viral transmission. METHODS: A cross-sectional study was conducted from February to December 2008; women with age of 18 to 45 years, with low risk for sexually transmitted disease (STD) were invited to participate. Blood samples were collected in filter paper, and HTLV-1/2 immunoenzymatic test (ELISA) was performed as a screening test. Women with reactive results were submitted to peripheral venous blood collection for ELISA repetition, followed by Western blot (WB) and real-time PCR to confirm and discriminate the infection between virus types 1 and 2. RESULTS: Of the 2,044 women tested, seven (0.3%) were ELISA reactive and confirmed positive (four were HTLV-1, and three were HTLV-2). All positive women were oriented not to breastfeed their newborns. CONCLUSIONS: This study showed that the virus is present in high prevalence in that population. Further studies covering other segments of the population are necessary to better characterize the presence of HTLV-1/2 in Maranhão and to elicit measures to prevent its spread. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 45 2 159 162 |
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HTLV-1/2 Gravidez Prevalência Maranhão Brasil Arctic medicine. Tropical medicine RC955-962 |
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HTLV-1/2 Gravidez Prevalência Maranhão Brasil Arctic medicine. Tropical medicine RC955-962 Verônica Guimarães de Souza Marina Lobato Martins Anna Bárbara de Freitas Carneiro-Proietti José Nélio Januário Roberto Vagner Puglia Ladeira Camila Moreira Serra Silva Claudyene Pires Samea Cristina Gomes Christiane de Souza Martins Elba Gomide Mochel High prevalence of HTLV-1 and 2 viruses in pregnant women in São Luis, state of Maranhão, Brazil |
topic_facet |
HTLV-1/2 Gravidez Prevalência Maranhão Brasil Arctic medicine. Tropical medicine RC955-962 |
description |
INTRODUCTION: Human T cell lymphotropic virus type 1 (HTLV-1) is endemic in the Caribbean, Japan, South America and regions of Africa. HTLV-2 is present in Native American populations and associated with IV drug use in Europe and North America. In Brazil, it is estimated that 1.5 million people are infected with HTLV-1/2. The study objective was to determine HTLV-1/2 prevalence in pregnant women in the prenatal care from three public services in São Luis, State of Maranhão, Brazil, and to counsel seropositive women to reduce viral transmission. METHODS: A cross-sectional study was conducted from February to December 2008; women with age of 18 to 45 years, with low risk for sexually transmitted disease (STD) were invited to participate. Blood samples were collected in filter paper, and HTLV-1/2 immunoenzymatic test (ELISA) was performed as a screening test. Women with reactive results were submitted to peripheral venous blood collection for ELISA repetition, followed by Western blot (WB) and real-time PCR to confirm and discriminate the infection between virus types 1 and 2. RESULTS: Of the 2,044 women tested, seven (0.3%) were ELISA reactive and confirmed positive (four were HTLV-1, and three were HTLV-2). All positive women were oriented not to breastfeed their newborns. CONCLUSIONS: This study showed that the virus is present in high prevalence in that population. Further studies covering other segments of the population are necessary to better characterize the presence of HTLV-1/2 in Maranhão and to elicit measures to prevent its spread. |
format |
Article in Journal/Newspaper |
author |
Verônica Guimarães de Souza Marina Lobato Martins Anna Bárbara de Freitas Carneiro-Proietti José Nélio Januário Roberto Vagner Puglia Ladeira Camila Moreira Serra Silva Claudyene Pires Samea Cristina Gomes Christiane de Souza Martins Elba Gomide Mochel |
author_facet |
Verônica Guimarães de Souza Marina Lobato Martins Anna Bárbara de Freitas Carneiro-Proietti José Nélio Januário Roberto Vagner Puglia Ladeira Camila Moreira Serra Silva Claudyene Pires Samea Cristina Gomes Christiane de Souza Martins Elba Gomide Mochel |
author_sort |
Verônica Guimarães de Souza |
title |
High prevalence of HTLV-1 and 2 viruses in pregnant women in São Luis, state of Maranhão, Brazil |
title_short |
High prevalence of HTLV-1 and 2 viruses in pregnant women in São Luis, state of Maranhão, Brazil |
title_full |
High prevalence of HTLV-1 and 2 viruses in pregnant women in São Luis, state of Maranhão, Brazil |
title_fullStr |
High prevalence of HTLV-1 and 2 viruses in pregnant women in São Luis, state of Maranhão, Brazil |
title_full_unstemmed |
High prevalence of HTLV-1 and 2 viruses in pregnant women in São Luis, state of Maranhão, Brazil |
title_sort |
high prevalence of htlv-1 and 2 viruses in pregnant women in são luis, state of maranhão, brazil |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2012 |
url |
https://doi.org/10.1590/S0037-86822012000200004 https://doaj.org/article/24ff0dec16584d51baa69864c2986650 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
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Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 45, Iss 2, Pp 159-162 (2012) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000200004&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/S0037-86822012000200004 https://doaj.org/article/24ff0dec16584d51baa69864c2986650 |
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https://doi.org/10.1590/S0037-86822012000200004 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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45 |
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159 |
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