Five-year field results and long-term effectiveness of 20 mg/kg liposomal amphotericin B (Ambisome) for visceral leishmaniasis in Bihar, India.

• Published in: PLoS Neglected Tropical Diseases
• Main Authors: Sakib Burza, Prabhat K Sinha, Raman Mahajan, María Angeles Lima, Gaurab Mitra, Neena Verma, Manica Balasegaram, Pradeep Das
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2014
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Azar
• Online Access: https://doi.org/10.1371/journal.pntd.0002603; https://doaj.org/article/2336b601f64040fd9778026f22ba049c

BACKGROUND: Visceral Leishmaniasis (VL; also known as Kala-azar) is an ultimately fatal disease endemic in Bihar. A 2007 observational cohort study in Bihar of 251 patients with VL treated with 20 mg/Kg intravenous liposomal amphotericin B (Ambisome) demonstrated a 98% cure rate at 6-months. Between...