Clinical manifestations, complications, and outcomes of patients with COVID-19 in Sudan: a multicenter observational study
Abstract Background Coronavirus disease 2019 (COVID-19) is a pandemic caused by a newly discovered coronavirus. Although clinical manifestations of COVID-19 are mainly pulmonary, some patients have other systemic manifestations. This study aimed to describe the clinical finding and outcomes in Sudan...
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ftdoajarticles:oai:doaj.org/article:219d7c2b33694239b83304b1ed0eaca7 2023-05-15T15:14:39+02:00 Clinical manifestations, complications, and outcomes of patients with COVID-19 in Sudan: a multicenter observational study Elfatih A. Hasabo Fatima A. Ayyad Sara A. M. Alam Eldeen Malaz K. Noureldaim Tibyan A. Abdallah Yousra T. Ahmed Safaa Badi Waleed K. Khalid Hind A. Mirghani Yossra A. Mohammed Lubaba A. Alkhider Saada A. Hamad Amna M. Tagelseed Ethar H. A. Elsheikh Noon H. Khalid Samia A. Mohammed Sara O. Elmobark Ola O. Ali Duaa A. Mohammed Ali Mohamed S. Muneer Heitham Awadalla Elfatih M. Malik 2021-11-01T00:00:00Z https://doi.org/10.1186/s41182-021-00382-4 https://doaj.org/article/219d7c2b33694239b83304b1ed0eaca7 EN eng BMC https://doi.org/10.1186/s41182-021-00382-4 https://doaj.org/toc/1349-4147 doi:10.1186/s41182-021-00382-4 1349-4147 https://doaj.org/article/219d7c2b33694239b83304b1ed0eaca7 Tropical Medicine and Health, Vol 49, Iss 1, Pp 1-13 (2021) COVID-19 Clinical manifestations In-hospital outcomes Complications Sudan Severity Arctic medicine. Tropical medicine RC955-962 article 2021 ftdoajarticles https://doi.org/10.1186/s41182-021-00382-4 2022-12-31T09:07:04Z Abstract Background Coronavirus disease 2019 (COVID-19) is a pandemic caused by a newly discovered coronavirus. Although clinical manifestations of COVID-19 are mainly pulmonary, some patients have other systemic manifestations. This study aimed to describe the clinical finding and outcomes in Sudanese patients diagnosed with COVID-19. Methods This retrospective observational study is based on documented files that included patients diagnosed with COVID-19 in seven selected hospitals inside Khartoum. Clinical manifestations, complications and outcomes were extracted from patients’ records using an extraction form designed for this study. Results Data of 243 patients diagnosed with COVID-19 were analyzed. The mean (SD) age in years was 55.8 (18.4). Out of 116 participants, 27 of them (23.3%) had severe disease, 15 (12.9%) were critically ill. 67.5% of patients were admitted to the hospital within 7 days from onset of symptoms; most of them were admitted to the wards (n = 140,72.5%). Fever (83.2%), cough (70.7%), and shortness of breath (69.2%) were the most commonly recorded clinical manifestations. Sepsis (9.8%) and acidosis (7.8%) were the most frequently reported complications. Death was the final outcome in 21.4% (56/243). Older age and presence of diabetes were found significantly associated with in-hospital death. The laboratory results showed high CRP in 85.6% (119/139), high ferritin in 88.9% (24/27), lactate dehydrogenase had a median of 409.0 (359–760), D-dimer had a median of 3.3 (1.2–16. 6), and 53/105 (50.5%) had low albumin. Conclusions Fever was the most mentioned sign among the participants, followed by fatigue. Cough and shortness of breath were the most commonly recorded pulmonary symptoms manifested. Our study showed multiple variables were associated with in-hospital death. The mortality rate was high among severe and critically ill patients diagnosed with COVID-19. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Tropical Medicine and Health 49 1 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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COVID-19 Clinical manifestations In-hospital outcomes Complications Sudan Severity Arctic medicine. Tropical medicine RC955-962 |
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COVID-19 Clinical manifestations In-hospital outcomes Complications Sudan Severity Arctic medicine. Tropical medicine RC955-962 Elfatih A. Hasabo Fatima A. Ayyad Sara A. M. Alam Eldeen Malaz K. Noureldaim Tibyan A. Abdallah Yousra T. Ahmed Safaa Badi Waleed K. Khalid Hind A. Mirghani Yossra A. Mohammed Lubaba A. Alkhider Saada A. Hamad Amna M. Tagelseed Ethar H. A. Elsheikh Noon H. Khalid Samia A. Mohammed Sara O. Elmobark Ola O. Ali Duaa A. Mohammed Ali Mohamed S. Muneer Heitham Awadalla Elfatih M. Malik Clinical manifestations, complications, and outcomes of patients with COVID-19 in Sudan: a multicenter observational study |
topic_facet |
COVID-19 Clinical manifestations In-hospital outcomes Complications Sudan Severity Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract Background Coronavirus disease 2019 (COVID-19) is a pandemic caused by a newly discovered coronavirus. Although clinical manifestations of COVID-19 are mainly pulmonary, some patients have other systemic manifestations. This study aimed to describe the clinical finding and outcomes in Sudanese patients diagnosed with COVID-19. Methods This retrospective observational study is based on documented files that included patients diagnosed with COVID-19 in seven selected hospitals inside Khartoum. Clinical manifestations, complications and outcomes were extracted from patients’ records using an extraction form designed for this study. Results Data of 243 patients diagnosed with COVID-19 were analyzed. The mean (SD) age in years was 55.8 (18.4). Out of 116 participants, 27 of them (23.3%) had severe disease, 15 (12.9%) were critically ill. 67.5% of patients were admitted to the hospital within 7 days from onset of symptoms; most of them were admitted to the wards (n = 140,72.5%). Fever (83.2%), cough (70.7%), and shortness of breath (69.2%) were the most commonly recorded clinical manifestations. Sepsis (9.8%) and acidosis (7.8%) were the most frequently reported complications. Death was the final outcome in 21.4% (56/243). Older age and presence of diabetes were found significantly associated with in-hospital death. The laboratory results showed high CRP in 85.6% (119/139), high ferritin in 88.9% (24/27), lactate dehydrogenase had a median of 409.0 (359–760), D-dimer had a median of 3.3 (1.2–16. 6), and 53/105 (50.5%) had low albumin. Conclusions Fever was the most mentioned sign among the participants, followed by fatigue. Cough and shortness of breath were the most commonly recorded pulmonary symptoms manifested. Our study showed multiple variables were associated with in-hospital death. The mortality rate was high among severe and critically ill patients diagnosed with COVID-19. |
format |
Article in Journal/Newspaper |
author |
Elfatih A. Hasabo Fatima A. Ayyad Sara A. M. Alam Eldeen Malaz K. Noureldaim Tibyan A. Abdallah Yousra T. Ahmed Safaa Badi Waleed K. Khalid Hind A. Mirghani Yossra A. Mohammed Lubaba A. Alkhider Saada A. Hamad Amna M. Tagelseed Ethar H. A. Elsheikh Noon H. Khalid Samia A. Mohammed Sara O. Elmobark Ola O. Ali Duaa A. Mohammed Ali Mohamed S. Muneer Heitham Awadalla Elfatih M. Malik |
author_facet |
Elfatih A. Hasabo Fatima A. Ayyad Sara A. M. Alam Eldeen Malaz K. Noureldaim Tibyan A. Abdallah Yousra T. Ahmed Safaa Badi Waleed K. Khalid Hind A. Mirghani Yossra A. Mohammed Lubaba A. Alkhider Saada A. Hamad Amna M. Tagelseed Ethar H. A. Elsheikh Noon H. Khalid Samia A. Mohammed Sara O. Elmobark Ola O. Ali Duaa A. Mohammed Ali Mohamed S. Muneer Heitham Awadalla Elfatih M. Malik |
author_sort |
Elfatih A. Hasabo |
title |
Clinical manifestations, complications, and outcomes of patients with COVID-19 in Sudan: a multicenter observational study |
title_short |
Clinical manifestations, complications, and outcomes of patients with COVID-19 in Sudan: a multicenter observational study |
title_full |
Clinical manifestations, complications, and outcomes of patients with COVID-19 in Sudan: a multicenter observational study |
title_fullStr |
Clinical manifestations, complications, and outcomes of patients with COVID-19 in Sudan: a multicenter observational study |
title_full_unstemmed |
Clinical manifestations, complications, and outcomes of patients with COVID-19 in Sudan: a multicenter observational study |
title_sort |
clinical manifestations, complications, and outcomes of patients with covid-19 in sudan: a multicenter observational study |
publisher |
BMC |
publishDate |
2021 |
url |
https://doi.org/10.1186/s41182-021-00382-4 https://doaj.org/article/219d7c2b33694239b83304b1ed0eaca7 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Tropical Medicine and Health, Vol 49, Iss 1, Pp 1-13 (2021) |
op_relation |
https://doi.org/10.1186/s41182-021-00382-4 https://doaj.org/toc/1349-4147 doi:10.1186/s41182-021-00382-4 1349-4147 https://doaj.org/article/219d7c2b33694239b83304b1ed0eaca7 |
op_doi |
https://doi.org/10.1186/s41182-021-00382-4 |
container_title |
Tropical Medicine and Health |
container_volume |
49 |
container_issue |
1 |
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1766345088110166016 |