BEHAVIORAL AND MEMORY CHANGES IN Mus musculus COINFECTED BY Toxocara canis AND Toxoplasma gondii
Several researchers have stated that parasites can alter the behavior of their hosts, in order to increase the transmission rate, principally when prey-predator relationships are a reliable way of infection transmission. The aim of this study was to verify the occurrence of changes in anxiety and sh...
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ftdoajarticles:oai:doaj.org/article:216fb6962de94bb89adea926eedf0e45 2024-09-09T19:26:38+00:00 BEHAVIORAL AND MEMORY CHANGES IN Mus musculus COINFECTED BY Toxocara canis AND Toxoplasma gondii Flávia Motta Corrêa Pedro Paulo Chieffi Susana A. Zevallos Lescano Sergio Vieira dos Santos 2014-07-01T00:00:00Z https://doi.org/10.1590/S0036-46652014000400014 https://doaj.org/article/216fb6962de94bb89adea926eedf0e45 EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652014000400353&lng=en&tlng=en https://doaj.org/toc/1678-9946 1678-9946 doi:10.1590/S0036-46652014000400014 https://doaj.org/article/216fb6962de94bb89adea926eedf0e45 Revista do Instituto de Medicina Tropical de São Paulo, Vol 56, Iss 4, Pp 353-356 (2014) Mus musculus Toxocara canis Toxoplasma gondii Concomitant infections Behavior alterations Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2014 ftdoajarticles https://doi.org/10.1590/S0036-46652014000400014 2024-08-05T17:49:31Z Several researchers have stated that parasites can alter the behavior of their hosts, in order to increase the transmission rate, principally when prey-predator relationships are a reliable way of infection transmission. The aim of this study was to verify the occurrence of changes in anxiety and short-term memory patterns in experimentally infected Mus musculus by Toxocara canis and/or Toxoplasma gondii. Forty male Mus musculus (Balb/c) eight-week-old were divided into four groups of 10 mice each. One group was infected with 300 eggs of Toxocara canis; a second group was submitted to infection with 10 cysts of Toxoplasma gondii; a third group was concomitantly infected with both parasites with the same inoculums and the last group was maintained without infection. The anxiety levels were evaluated using an elevated plus maze and an actometer; the short-term memory was determined by a two-way active avoidance equipment. The determination of anxiety levels were conducted 40 and 70 days after infection and the short-term memory was evaluated 140 days after infection. Mice chronically infected by Toxoplasma gondii showed impaired learning and short-term memory, but no significant differences were found in mice infected by Toxocara canis or concomitantly infected by Toxocara canis and Toxoplasma gondii when compared to non infected mice. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 56 4 353 356 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Mus musculus Toxocara canis Toxoplasma gondii Concomitant infections Behavior alterations Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Mus musculus Toxocara canis Toxoplasma gondii Concomitant infections Behavior alterations Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Flávia Motta Corrêa Pedro Paulo Chieffi Susana A. Zevallos Lescano Sergio Vieira dos Santos BEHAVIORAL AND MEMORY CHANGES IN Mus musculus COINFECTED BY Toxocara canis AND Toxoplasma gondii |
topic_facet |
Mus musculus Toxocara canis Toxoplasma gondii Concomitant infections Behavior alterations Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Several researchers have stated that parasites can alter the behavior of their hosts, in order to increase the transmission rate, principally when prey-predator relationships are a reliable way of infection transmission. The aim of this study was to verify the occurrence of changes in anxiety and short-term memory patterns in experimentally infected Mus musculus by Toxocara canis and/or Toxoplasma gondii. Forty male Mus musculus (Balb/c) eight-week-old were divided into four groups of 10 mice each. One group was infected with 300 eggs of Toxocara canis; a second group was submitted to infection with 10 cysts of Toxoplasma gondii; a third group was concomitantly infected with both parasites with the same inoculums and the last group was maintained without infection. The anxiety levels were evaluated using an elevated plus maze and an actometer; the short-term memory was determined by a two-way active avoidance equipment. The determination of anxiety levels were conducted 40 and 70 days after infection and the short-term memory was evaluated 140 days after infection. Mice chronically infected by Toxoplasma gondii showed impaired learning and short-term memory, but no significant differences were found in mice infected by Toxocara canis or concomitantly infected by Toxocara canis and Toxoplasma gondii when compared to non infected mice. |
format |
Article in Journal/Newspaper |
author |
Flávia Motta Corrêa Pedro Paulo Chieffi Susana A. Zevallos Lescano Sergio Vieira dos Santos |
author_facet |
Flávia Motta Corrêa Pedro Paulo Chieffi Susana A. Zevallos Lescano Sergio Vieira dos Santos |
author_sort |
Flávia Motta Corrêa |
title |
BEHAVIORAL AND MEMORY CHANGES IN Mus musculus COINFECTED BY Toxocara canis AND Toxoplasma gondii |
title_short |
BEHAVIORAL AND MEMORY CHANGES IN Mus musculus COINFECTED BY Toxocara canis AND Toxoplasma gondii |
title_full |
BEHAVIORAL AND MEMORY CHANGES IN Mus musculus COINFECTED BY Toxocara canis AND Toxoplasma gondii |
title_fullStr |
BEHAVIORAL AND MEMORY CHANGES IN Mus musculus COINFECTED BY Toxocara canis AND Toxoplasma gondii |
title_full_unstemmed |
BEHAVIORAL AND MEMORY CHANGES IN Mus musculus COINFECTED BY Toxocara canis AND Toxoplasma gondii |
title_sort |
behavioral and memory changes in mus musculus coinfected by toxocara canis and toxoplasma gondii |
publisher |
Universidade de São Paulo (USP) |
publishDate |
2014 |
url |
https://doi.org/10.1590/S0036-46652014000400014 https://doaj.org/article/216fb6962de94bb89adea926eedf0e45 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 56, Iss 4, Pp 353-356 (2014) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652014000400353&lng=en&tlng=en https://doaj.org/toc/1678-9946 1678-9946 doi:10.1590/S0036-46652014000400014 https://doaj.org/article/216fb6962de94bb89adea926eedf0e45 |
op_doi |
https://doi.org/10.1590/S0036-46652014000400014 |
container_title |
Revista do Instituto de Medicina Tropical de São Paulo |
container_volume |
56 |
container_issue |
4 |
container_start_page |
353 |
op_container_end_page |
356 |
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1809896212008009728 |