Distribution of HLA-DRB1 alleles in BRICS countries with a high tuberculosis burden: a systematic review and meta-analysis

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Alice Sarno, Cleidiane Borges Daltro, Carlos Mauricio Cardeal Mendes, Theolis Barbosa
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2021
• Subjects: Tuberculosis; Epitope-based vaccine; Rational vaccine design; Vaccine candidate; Major histocompatibility complex; Immunogenicity; Arctic medicine. Tropical medicine; RC955-962; Arctic; Calmette
• Online Access: https://doi.org/10.1590/0037-8682-0017-2021; https://doaj.org/article/20f7648d79984a97ae0b04f07ef1b314

Abstract INTRODUCTION: Tuberculosis (TB) is the leading cause of death worldwide caused by a single infectious disease agent. Brazil, Russia, India, China, and South Africa (BRICS) account for more than half of the world’s TB cases. Bacillus Calmette-Guérin (BCG) remains the only vaccine available d...