Outcomes of non-surgical treatment of chronic anal fissure: A comparative study
Background and objective: Chronic anal fissure is a common health problem related to high morbidity. The chemical option for treating chronic anal fissures is highly preferred. Methods: A clinical prospective comparative study was carried out in the General Surgery Outpatient Department in Rizgary T...
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Hawler Medical University
2023
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ftdoajarticles:oai:doaj.org/article:20d713ee0425488e9d21d7916ef54cec 2024-01-21T10:06:47+01:00 Outcomes of non-surgical treatment of chronic anal fissure: A comparative study Azhy Muhammed Dewana Baderkhan Saeed Ahmed Ahmed Abdulkadir Baban Rawand Musheer Haweizy 2023-12-01T00:00:00Z https://doi.org/10.15218/zjms.2023.031 https://doaj.org/article/20d713ee0425488e9d21d7916ef54cec EN eng Hawler Medical University https://zjms.hmu.edu.krd/index.php/zjms/article/view/903 https://doaj.org/toc/1995-5588 https://doaj.org/toc/1995-5596 doi:10.15218/zjms.2023.031 1995-5588 1995-5596 https://doaj.org/article/20d713ee0425488e9d21d7916ef54cec Zanco Journal of Medical Sciences, Vol 27, Iss 3, Pp 283-291 (2023) non-surgical treatment chronic anal fissure diltiazem Medicine R article 2023 ftdoajarticles https://doi.org/10.15218/zjms.2023.031 2023-12-24T01:41:14Z Background and objective: Chronic anal fissure is a common health problem related to high morbidity. The chemical option for treating chronic anal fissures is highly preferred. Methods: A clinical prospective comparative study was carried out in the General Surgery Outpatient Department in Rizgary Teaching Hospital, Erbil, KRG, during the period from January 2019 to December 2021,on a sample of 100 patients randomly recruited patients with chronic anal fissures divided into two groups with 50 participants each: the DTZ group, who received 2% diltiazem ointment, and the GTN group, who used 0.2% glyceryl trinitrate ointment twice daily for 6 consecutive weeks. The aim of the study is to compare the efficacy and effects of topical Diltiazem (DTZ) and topical glyceryl trinitrate (GTN) in the management of chronic anal fissures. Results: There was a highly significant association between fissure healing at the 4th week and patients treated with DTZ (P <0.001). A highly significant association was observed at the 6th week between fissure healing and DTZ treatment (P <0.001), while there was later a highly significant association between fissure healing at the 8th week and patients treated with GTN (P <0.001). A significant association was observed between treatment adverse effects and patients treated with GTN (P = 0.05). DTZ was found to be more effective for symptomatic relief than GTN. Conclusion: Both DTZ and GTN are effective in the treatment of chronic anal fissures, but treatment with DTZ is accompanied by faster healing and lower side effects. Article in Journal/Newspaper GTN-P Directory of Open Access Journals: DOAJ Articles Zanco Journal of Medical Sciences 27 3 283 291 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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language |
English |
topic |
non-surgical treatment chronic anal fissure diltiazem Medicine R |
spellingShingle |
non-surgical treatment chronic anal fissure diltiazem Medicine R Azhy Muhammed Dewana Baderkhan Saeed Ahmed Ahmed Abdulkadir Baban Rawand Musheer Haweizy Outcomes of non-surgical treatment of chronic anal fissure: A comparative study |
topic_facet |
non-surgical treatment chronic anal fissure diltiazem Medicine R |
description |
Background and objective: Chronic anal fissure is a common health problem related to high morbidity. The chemical option for treating chronic anal fissures is highly preferred. Methods: A clinical prospective comparative study was carried out in the General Surgery Outpatient Department in Rizgary Teaching Hospital, Erbil, KRG, during the period from January 2019 to December 2021,on a sample of 100 patients randomly recruited patients with chronic anal fissures divided into two groups with 50 participants each: the DTZ group, who received 2% diltiazem ointment, and the GTN group, who used 0.2% glyceryl trinitrate ointment twice daily for 6 consecutive weeks. The aim of the study is to compare the efficacy and effects of topical Diltiazem (DTZ) and topical glyceryl trinitrate (GTN) in the management of chronic anal fissures. Results: There was a highly significant association between fissure healing at the 4th week and patients treated with DTZ (P <0.001). A highly significant association was observed at the 6th week between fissure healing and DTZ treatment (P <0.001), while there was later a highly significant association between fissure healing at the 8th week and patients treated with GTN (P <0.001). A significant association was observed between treatment adverse effects and patients treated with GTN (P = 0.05). DTZ was found to be more effective for symptomatic relief than GTN. Conclusion: Both DTZ and GTN are effective in the treatment of chronic anal fissures, but treatment with DTZ is accompanied by faster healing and lower side effects. |
format |
Article in Journal/Newspaper |
author |
Azhy Muhammed Dewana Baderkhan Saeed Ahmed Ahmed Abdulkadir Baban Rawand Musheer Haweizy |
author_facet |
Azhy Muhammed Dewana Baderkhan Saeed Ahmed Ahmed Abdulkadir Baban Rawand Musheer Haweizy |
author_sort |
Azhy Muhammed Dewana |
title |
Outcomes of non-surgical treatment of chronic anal fissure: A comparative study |
title_short |
Outcomes of non-surgical treatment of chronic anal fissure: A comparative study |
title_full |
Outcomes of non-surgical treatment of chronic anal fissure: A comparative study |
title_fullStr |
Outcomes of non-surgical treatment of chronic anal fissure: A comparative study |
title_full_unstemmed |
Outcomes of non-surgical treatment of chronic anal fissure: A comparative study |
title_sort |
outcomes of non-surgical treatment of chronic anal fissure: a comparative study |
publisher |
Hawler Medical University |
publishDate |
2023 |
url |
https://doi.org/10.15218/zjms.2023.031 https://doaj.org/article/20d713ee0425488e9d21d7916ef54cec |
genre |
GTN-P |
genre_facet |
GTN-P |
op_source |
Zanco Journal of Medical Sciences, Vol 27, Iss 3, Pp 283-291 (2023) |
op_relation |
https://zjms.hmu.edu.krd/index.php/zjms/article/view/903 https://doaj.org/toc/1995-5588 https://doaj.org/toc/1995-5596 doi:10.15218/zjms.2023.031 1995-5588 1995-5596 https://doaj.org/article/20d713ee0425488e9d21d7916ef54cec |
op_doi |
https://doi.org/10.15218/zjms.2023.031 |
container_title |
Zanco Journal of Medical Sciences |
container_volume |
27 |
container_issue |
3 |
container_start_page |
283 |
op_container_end_page |
291 |
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