Malaria prevalence among pregnant women in two districts with differing endemicity in Chhattisgarh, India
Abstract Background In India, malaria is not uniformly distributed. Chhattisgarh is a highly malarious state where both Plasmodium falciparum and Plasmodium vivax are prevalent with a preponderance of P. falciparum . Malaria in pregnancy (MIP), especially when caused by P. falciparum , poses substan...
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ftdoajarticles:oai:doaj.org/article:205b08a899c94831a2f3dd55ce892b78 2023-05-15T15:17:16+02:00 Malaria prevalence among pregnant women in two districts with differing endemicity in Chhattisgarh, India Singh Neeru Singh Mrigendra P Wylie Blair J Hussain Mobassir Kojo Yeboah A Shekhar Chander Sabin Lora Desai Meghna Udhayakumar V Hamer Davidson H 2012-08-01T00:00:00Z https://doi.org/10.1186/1475-2875-11-274 https://doaj.org/article/205b08a899c94831a2f3dd55ce892b78 EN eng BMC http://www.malariajournal.com/content/11/1/274 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-11-274 1475-2875 https://doaj.org/article/205b08a899c94831a2f3dd55ce892b78 Malaria Journal, Vol 11, Iss 1, p 274 (2012) Pregnancy Malaria India Plasmodium falciparum Plasmodium vivax Anaemia Low birth weight Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2012 ftdoajarticles https://doi.org/10.1186/1475-2875-11-274 2022-12-31T08:48:32Z Abstract Background In India, malaria is not uniformly distributed. Chhattisgarh is a highly malarious state where both Plasmodium falciparum and Plasmodium vivax are prevalent with a preponderance of P. falciparum . Malaria in pregnancy (MIP), especially when caused by P. falciparum , poses substantial risk to the mother and foetus by increasing the risk of foetal death, prematurity, low birth weight (LBW), and maternal anaemia. These risks vary between areas with stable and unstable transmission. The specific objectives of this study were to determine the prevalence of malaria, its association with maternal and birth outcomes, and use of anti-malarial preventive measures for development of evidence based interventions to reduce the burden of MIP. Methods A cross-sectional study of pregnant women presenting to antenatal clinics (ANC) or delivery units (DU), or hospitalized for non-obstetric illness was conducted over 12 months in high (Bastar) and low (Rajnandgaon) transmission districts in Chhattisgarh state. Intensity of transmission was defined on the basis of slide positivity rates with a high proportion due to P. falciparum . In each district, a rural and an urban health facility was selected. Results Prevalence of peripheral parasitaemia was low: 1.3% (35/2696) among women at ANCs and 1.9% at DUs (19/1025). Peripheral parasitaemia was significantly more common in Bastar (2.8%) than in Rajnandgaon (0.1%) (p < 0.0001). On multivariate analysis of ANC participants, residence in Bastar district (stable malaria transmission) was strongly associated with peripheral parasitaemia (adjusted OR [aOR] 43.4; 95% CI, 5.6-335.2). Additional covariates associated with parasitaemia were moderate anaemia (aOR 3.7; 95% CI 1.8-7.7), fever within the past week (aOR 3.2; 95% CI 1.2-8.6), and lack of formal education (aOR 4.6; 95% CI 2.0-10.7). Similarly, analysis of DU participants revealed that moderate anaemia (aOR 2.5; 95% CI 1.1-5.4) and fever within the past week (aOR 5.8; 95% CI 2.4-13.9) were strongly associated ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 11 1 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
topic |
Pregnancy Malaria India Plasmodium falciparum Plasmodium vivax Anaemia Low birth weight Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Pregnancy Malaria India Plasmodium falciparum Plasmodium vivax Anaemia Low birth weight Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Singh Neeru Singh Mrigendra P Wylie Blair J Hussain Mobassir Kojo Yeboah A Shekhar Chander Sabin Lora Desai Meghna Udhayakumar V Hamer Davidson H Malaria prevalence among pregnant women in two districts with differing endemicity in Chhattisgarh, India |
topic_facet |
Pregnancy Malaria India Plasmodium falciparum Plasmodium vivax Anaemia Low birth weight Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background In India, malaria is not uniformly distributed. Chhattisgarh is a highly malarious state where both Plasmodium falciparum and Plasmodium vivax are prevalent with a preponderance of P. falciparum . Malaria in pregnancy (MIP), especially when caused by P. falciparum , poses substantial risk to the mother and foetus by increasing the risk of foetal death, prematurity, low birth weight (LBW), and maternal anaemia. These risks vary between areas with stable and unstable transmission. The specific objectives of this study were to determine the prevalence of malaria, its association with maternal and birth outcomes, and use of anti-malarial preventive measures for development of evidence based interventions to reduce the burden of MIP. Methods A cross-sectional study of pregnant women presenting to antenatal clinics (ANC) or delivery units (DU), or hospitalized for non-obstetric illness was conducted over 12 months in high (Bastar) and low (Rajnandgaon) transmission districts in Chhattisgarh state. Intensity of transmission was defined on the basis of slide positivity rates with a high proportion due to P. falciparum . In each district, a rural and an urban health facility was selected. Results Prevalence of peripheral parasitaemia was low: 1.3% (35/2696) among women at ANCs and 1.9% at DUs (19/1025). Peripheral parasitaemia was significantly more common in Bastar (2.8%) than in Rajnandgaon (0.1%) (p < 0.0001). On multivariate analysis of ANC participants, residence in Bastar district (stable malaria transmission) was strongly associated with peripheral parasitaemia (adjusted OR [aOR] 43.4; 95% CI, 5.6-335.2). Additional covariates associated with parasitaemia were moderate anaemia (aOR 3.7; 95% CI 1.8-7.7), fever within the past week (aOR 3.2; 95% CI 1.2-8.6), and lack of formal education (aOR 4.6; 95% CI 2.0-10.7). Similarly, analysis of DU participants revealed that moderate anaemia (aOR 2.5; 95% CI 1.1-5.4) and fever within the past week (aOR 5.8; 95% CI 2.4-13.9) were strongly associated ... |
format |
Article in Journal/Newspaper |
author |
Singh Neeru Singh Mrigendra P Wylie Blair J Hussain Mobassir Kojo Yeboah A Shekhar Chander Sabin Lora Desai Meghna Udhayakumar V Hamer Davidson H |
author_facet |
Singh Neeru Singh Mrigendra P Wylie Blair J Hussain Mobassir Kojo Yeboah A Shekhar Chander Sabin Lora Desai Meghna Udhayakumar V Hamer Davidson H |
author_sort |
Singh Neeru |
title |
Malaria prevalence among pregnant women in two districts with differing endemicity in Chhattisgarh, India |
title_short |
Malaria prevalence among pregnant women in two districts with differing endemicity in Chhattisgarh, India |
title_full |
Malaria prevalence among pregnant women in two districts with differing endemicity in Chhattisgarh, India |
title_fullStr |
Malaria prevalence among pregnant women in two districts with differing endemicity in Chhattisgarh, India |
title_full_unstemmed |
Malaria prevalence among pregnant women in two districts with differing endemicity in Chhattisgarh, India |
title_sort |
malaria prevalence among pregnant women in two districts with differing endemicity in chhattisgarh, india |
publisher |
BMC |
publishDate |
2012 |
url |
https://doi.org/10.1186/1475-2875-11-274 https://doaj.org/article/205b08a899c94831a2f3dd55ce892b78 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 11, Iss 1, p 274 (2012) |
op_relation |
http://www.malariajournal.com/content/11/1/274 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-11-274 1475-2875 https://doaj.org/article/205b08a899c94831a2f3dd55ce892b78 |
op_doi |
https://doi.org/10.1186/1475-2875-11-274 |
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Malaria Journal |
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11 |
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