Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil
Abstract: INTRODUCTION: Few studies have addressed the primary characteristics of patients infected with hepatitis B virus (HBV) in the general population, especially those living in small- and medium-sized cities in Brazil. We aimed to determine the clinical, demographic, and epidemiologic characte...
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ftdoajarticles:oai:doaj.org/article:1f942bcd7f6f474f97f2679d88f7b93b 2023-05-15T15:09:55+02:00 Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil Luiz Euribel Prestes-Carneiro Jessyka Thaiza Menezes Vieira Luiza Bellintani Isaac Alexandre Martins Portelinha Filho 2016-02-01T00:00:00Z https://doi.org/10.1590/0037-8682-0315-2015 https://doaj.org/article/1f942bcd7f6f474f97f2679d88f7b93b EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000100024&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0315-2015 https://doaj.org/article/1f942bcd7f6f474f97f2679d88f7b93b Revista da Sociedade Brasileira de Medicina Tropical, Vol 49, Iss 1, Pp 24-28 (2016) Hepatitis B vírus Epidemiology Risk factors Antiviral treatment Arctic medicine. Tropical medicine RC955-962 article 2016 ftdoajarticles https://doi.org/10.1590/0037-8682-0315-2015 2022-12-31T02:58:28Z Abstract: INTRODUCTION: Few studies have addressed the primary characteristics of patients infected with hepatitis B virus (HBV) in the general population, especially those living in small- and medium-sized cities in Brazil. We aimed to determine the clinical, demographic, and epidemiologic characteristics of patients diagnosed with HBV who were followed up at an infectious diseases clinic of a public hospital in State of São Paulo, Brazil. METHODS: Medical records of patients aged >18 years and diagnosed with HBV infection between January 2000 and December 2013 were reviewed. RESULTS: Seventy-five patients were enrolled with male-female main infection-associated risk factors; 9 (12%) were co-infected with human immunodeficiency virus (HIV), 5 (6.7%) with hepatitis C virus (HCV), and 3 (4%) were co-infected with both HIV and HCV. Antiviral HBV therapy was applied in 21 (28%) patients and tenofovir monotherapy was the most prescribed medication. After approximately 2 years of antiviral treatment, the HBV-DNA viral load was undetectable in 12 (92.3%) patients and lower levels of alanine aminotransferase were found in these patients. CONCLUSIONS: Over a 13-year interval, very few individuals infected with HBV were identified, highlighting the barriers for caring for patients with HBV in developing countries. New measures need to be implemented to complement curative practices. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 49 1 24 28 |
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Directory of Open Access Journals: DOAJ Articles |
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Hepatitis B vírus Epidemiology Risk factors Antiviral treatment Arctic medicine. Tropical medicine RC955-962 |
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Hepatitis B vírus Epidemiology Risk factors Antiviral treatment Arctic medicine. Tropical medicine RC955-962 Luiz Euribel Prestes-Carneiro Jessyka Thaiza Menezes Vieira Luiza Bellintani Isaac Alexandre Martins Portelinha Filho Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil |
topic_facet |
Hepatitis B vírus Epidemiology Risk factors Antiviral treatment Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract: INTRODUCTION: Few studies have addressed the primary characteristics of patients infected with hepatitis B virus (HBV) in the general population, especially those living in small- and medium-sized cities in Brazil. We aimed to determine the clinical, demographic, and epidemiologic characteristics of patients diagnosed with HBV who were followed up at an infectious diseases clinic of a public hospital in State of São Paulo, Brazil. METHODS: Medical records of patients aged >18 years and diagnosed with HBV infection between January 2000 and December 2013 were reviewed. RESULTS: Seventy-five patients were enrolled with male-female main infection-associated risk factors; 9 (12%) were co-infected with human immunodeficiency virus (HIV), 5 (6.7%) with hepatitis C virus (HCV), and 3 (4%) were co-infected with both HIV and HCV. Antiviral HBV therapy was applied in 21 (28%) patients and tenofovir monotherapy was the most prescribed medication. After approximately 2 years of antiviral treatment, the HBV-DNA viral load was undetectable in 12 (92.3%) patients and lower levels of alanine aminotransferase were found in these patients. CONCLUSIONS: Over a 13-year interval, very few individuals infected with HBV were identified, highlighting the barriers for caring for patients with HBV in developing countries. New measures need to be implemented to complement curative practices. |
format |
Article in Journal/Newspaper |
author |
Luiz Euribel Prestes-Carneiro Jessyka Thaiza Menezes Vieira Luiza Bellintani Isaac Alexandre Martins Portelinha Filho |
author_facet |
Luiz Euribel Prestes-Carneiro Jessyka Thaiza Menezes Vieira Luiza Bellintani Isaac Alexandre Martins Portelinha Filho |
author_sort |
Luiz Euribel Prestes-Carneiro |
title |
Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil |
title_short |
Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil |
title_full |
Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil |
title_fullStr |
Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil |
title_full_unstemmed |
Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil |
title_sort |
clinical, demographic, and epidemiologic characteristics of hepatitis b virus-infected patients at a tertiary public hospital in presidente prudente, state of são paulo, brazil |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2016 |
url |
https://doi.org/10.1590/0037-8682-0315-2015 https://doaj.org/article/1f942bcd7f6f474f97f2679d88f7b93b |
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Arctic |
geographic_facet |
Arctic |
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Arctic |
genre_facet |
Arctic |
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Revista da Sociedade Brasileira de Medicina Tropical, Vol 49, Iss 1, Pp 24-28 (2016) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000100024&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0315-2015 https://doaj.org/article/1f942bcd7f6f474f97f2679d88f7b93b |
op_doi |
https://doi.org/10.1590/0037-8682-0315-2015 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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49 |
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24 |
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