Helicobacter pylori among symptomatic Egyptian children: prevalence, risk factors, and effect on growth
Abstract Aim This study was carried out to determine the prevalence and predictors of Helicobacter pylori (H. pylori) infection among symptomatic children and the effect on growth. Methods A cross-sectional study was conducted in the Outpatient Clinics of the Gastroenterology Unit of the Pediatric H...
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ftdoajarticles:oai:doaj.org/article:1f8314ae534d4e9abe78b2105cbfae17 2023-05-15T15:16:19+02:00 Helicobacter pylori among symptomatic Egyptian children: prevalence, risk factors, and effect on growth Yasmine Samir Galal Carolyne Morcos Ghobrial John Rene Labib Maha Elsayed Abou-Zekri 2019-05-01T00:00:00Z https://doi.org/10.1186/s42506-019-0017-6 https://doaj.org/article/1f8314ae534d4e9abe78b2105cbfae17 EN eng SpringerOpen http://link.springer.com/article/10.1186/s42506-019-0017-6 https://doaj.org/toc/2090-262X doi:10.1186/s42506-019-0017-6 2090-262X https://doaj.org/article/1f8314ae534d4e9abe78b2105cbfae17 Journal of the Egyptian Public Health Association, Vol 94, Iss 1, Pp 1-8 (2019) Helicobacter pylori Prevalence Growth parameters Malabsorption Iron-deficiency anemia Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2019 ftdoajarticles https://doi.org/10.1186/s42506-019-0017-6 2022-12-31T11:11:25Z Abstract Aim This study was carried out to determine the prevalence and predictors of Helicobacter pylori (H. pylori) infection among symptomatic children and the effect on growth. Methods A cross-sectional study was conducted in the Outpatient Clinics of the Gastroenterology Unit of the Pediatric Hospital, Cairo University. A total of 630 children complaining of any symptoms or signs suspicious of H. pylori infection were enrolled. Weight and height were measured for each child, and the standard deviation scores (Z-scores) for weight-for-age (WAZ), weight-for-height (WHZ), and height-for-age (HAZ) were calculated. H. pylori was diagnosed using a stool antigen test. Results The overall prevalence of infection was 64.6%. Socio-demographic variables significantly associated with H. pylori were residence in Upper Egypt (P = 0.013) and rural areas (P = 0.004), illiteracy of mothers (P = 0.017), household crowding index ≥ 3 (P = 0.011), absence of pure water supply (P = 0.005), and eating from street vendors (P < 0.001). Values of WAZ [median, interquartile range (IQR) in infected = − 1.3(− 2.7 to − 0.4) and non-infected = − 0.7(− 2.1 to − 0.1), P < 0.001], HAZ (P = 0.036), and WHZ (P = 0.005) were significantly lower in children infected with H. pylori. After performing a backward logistic regression analysis, eating from street vendors (OR = 1.879, 95% CI 1.346–2.625, P < 0.001), absence of pure water supply (OR = 1.725, 95% CI 1.162–2.561, P = 0.007), and overcrowding (OR = 1.547, 95% CI 1.100–2.177, P = 0.012) remained the significant predictors of H. pylori infection. Conclusion A high prevalence of H. pylori infection among symptomatic children was detected. The extra-digestive effects of H. pylori were revealed in the form of affection of growth parameters and reduced levels of serum hemoglobin, iron, and ferritin. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of the Egyptian Public Health Association 94 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Helicobacter pylori Prevalence Growth parameters Malabsorption Iron-deficiency anemia Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Helicobacter pylori Prevalence Growth parameters Malabsorption Iron-deficiency anemia Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Yasmine Samir Galal Carolyne Morcos Ghobrial John Rene Labib Maha Elsayed Abou-Zekri Helicobacter pylori among symptomatic Egyptian children: prevalence, risk factors, and effect on growth |
topic_facet |
Helicobacter pylori Prevalence Growth parameters Malabsorption Iron-deficiency anemia Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Abstract Aim This study was carried out to determine the prevalence and predictors of Helicobacter pylori (H. pylori) infection among symptomatic children and the effect on growth. Methods A cross-sectional study was conducted in the Outpatient Clinics of the Gastroenterology Unit of the Pediatric Hospital, Cairo University. A total of 630 children complaining of any symptoms or signs suspicious of H. pylori infection were enrolled. Weight and height were measured for each child, and the standard deviation scores (Z-scores) for weight-for-age (WAZ), weight-for-height (WHZ), and height-for-age (HAZ) were calculated. H. pylori was diagnosed using a stool antigen test. Results The overall prevalence of infection was 64.6%. Socio-demographic variables significantly associated with H. pylori were residence in Upper Egypt (P = 0.013) and rural areas (P = 0.004), illiteracy of mothers (P = 0.017), household crowding index ≥ 3 (P = 0.011), absence of pure water supply (P = 0.005), and eating from street vendors (P < 0.001). Values of WAZ [median, interquartile range (IQR) in infected = − 1.3(− 2.7 to − 0.4) and non-infected = − 0.7(− 2.1 to − 0.1), P < 0.001], HAZ (P = 0.036), and WHZ (P = 0.005) were significantly lower in children infected with H. pylori. After performing a backward logistic regression analysis, eating from street vendors (OR = 1.879, 95% CI 1.346–2.625, P < 0.001), absence of pure water supply (OR = 1.725, 95% CI 1.162–2.561, P = 0.007), and overcrowding (OR = 1.547, 95% CI 1.100–2.177, P = 0.012) remained the significant predictors of H. pylori infection. Conclusion A high prevalence of H. pylori infection among symptomatic children was detected. The extra-digestive effects of H. pylori were revealed in the form of affection of growth parameters and reduced levels of serum hemoglobin, iron, and ferritin. |
format |
Article in Journal/Newspaper |
author |
Yasmine Samir Galal Carolyne Morcos Ghobrial John Rene Labib Maha Elsayed Abou-Zekri |
author_facet |
Yasmine Samir Galal Carolyne Morcos Ghobrial John Rene Labib Maha Elsayed Abou-Zekri |
author_sort |
Yasmine Samir Galal |
title |
Helicobacter pylori among symptomatic Egyptian children: prevalence, risk factors, and effect on growth |
title_short |
Helicobacter pylori among symptomatic Egyptian children: prevalence, risk factors, and effect on growth |
title_full |
Helicobacter pylori among symptomatic Egyptian children: prevalence, risk factors, and effect on growth |
title_fullStr |
Helicobacter pylori among symptomatic Egyptian children: prevalence, risk factors, and effect on growth |
title_full_unstemmed |
Helicobacter pylori among symptomatic Egyptian children: prevalence, risk factors, and effect on growth |
title_sort |
helicobacter pylori among symptomatic egyptian children: prevalence, risk factors, and effect on growth |
publisher |
SpringerOpen |
publishDate |
2019 |
url |
https://doi.org/10.1186/s42506-019-0017-6 https://doaj.org/article/1f8314ae534d4e9abe78b2105cbfae17 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of the Egyptian Public Health Association, Vol 94, Iss 1, Pp 1-8 (2019) |
op_relation |
http://link.springer.com/article/10.1186/s42506-019-0017-6 https://doaj.org/toc/2090-262X doi:10.1186/s42506-019-0017-6 2090-262X https://doaj.org/article/1f8314ae534d4e9abe78b2105cbfae17 |
op_doi |
https://doi.org/10.1186/s42506-019-0017-6 |
container_title |
Journal of the Egyptian Public Health Association |
container_volume |
94 |
container_issue |
1 |
_version_ |
1766346611805388800 |