Frequency and distribution of HPV genotypes in 800 genital samples of Ecuadorian men and women from the city of Guayaquil
ABSTRACT Even though there are data published on HPV epidemiology in Ecuador, the distribution of genotypes in Guayaquil, the largest city in the country, has not been previously determined in a study including including both, men and women. The present study aimed to determine the distribution of 3...
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ftdoajarticles:oai:doaj.org/article:1f71952dcb21429f8ff299296402c58e 2024-09-09T19:27:02+00:00 Frequency and distribution of HPV genotypes in 800 genital samples of Ecuadorian men and women from the city of Guayaquil Gustavo David García Muentes Marcia Adelaida Mendoza García Ramiro Israel Burgos Galárraga Kleber Ollague Cynthia Vargas Wachter Juan Carlos Ruiz Cabezas https://doi.org/10.1590/s1678-9946201961041 https://doaj.org/article/1f71952dcb21429f8ff299296402c58e EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652019005000606&lng=en&tlng=en https://doaj.org/toc/1678-9946 1678-9946 doi:10.1590/s1678-9946201961041 https://doaj.org/article/1f71952dcb21429f8ff299296402c58e Revista do Instituto de Medicina Tropical de São Paulo, Vol 61 HPV Ecuador Males and females HPV genotypes Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article ftdoajarticles https://doi.org/10.1590/s1678-9946201961041 2024-08-05T17:49:30Z ABSTRACT Even though there are data published on HPV epidemiology in Ecuador, the distribution of genotypes in Guayaquil, the largest city in the country, has not been previously determined in a study including including both, men and women. The present study aimed to determine the distribution of 37 HPV genotypes in genital samples from Ecuadorian men and women living in the city of Guayaquil. Genital samples included in daily diagnostic routine were analyzed by the 37 HPV GenoArray Diagnostic Kit (Hybribio® Ltd., Sheung Wan, Hong Kong). The relative frequency of detectable genotypes was determined. HPV relative frequency according to sample characteristics, including sex and age groups, was compared using c2 test. From the 800 samples (400 men and 400 women), 411 (51.38%) were positive for HPV DNA. The obtained frequency was higher among samples from men (253/400 or 63.25%) in comparison to samples from women (158/400 or 39.50%), with a p value <0.05. Samples from men showed a higher frequency of HPV genotypes 6, 16, 18 and 11, while among samples from women genotypes 39, 16, 6 and 58 were the most frequent. Considering male and female samples together, genotypes 6, 16, 39 and 11 presented the highest frequencies. HPV DNA was detected in half of the studied samples, with a higher frequency among samples from men. Genotype 39 was the most frequent among women, and ranked third when samples from men and women are analyzed together. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Guayaquil ENVELOPE(-59.767,-59.767,-62.449,-62.449) Revista do Instituto de Medicina Tropical de São Paulo 61 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
HPV Ecuador Males and females HPV genotypes Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
HPV Ecuador Males and females HPV genotypes Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Gustavo David García Muentes Marcia Adelaida Mendoza García Ramiro Israel Burgos Galárraga Kleber Ollague Cynthia Vargas Wachter Juan Carlos Ruiz Cabezas Frequency and distribution of HPV genotypes in 800 genital samples of Ecuadorian men and women from the city of Guayaquil |
topic_facet |
HPV Ecuador Males and females HPV genotypes Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
ABSTRACT Even though there are data published on HPV epidemiology in Ecuador, the distribution of genotypes in Guayaquil, the largest city in the country, has not been previously determined in a study including including both, men and women. The present study aimed to determine the distribution of 37 HPV genotypes in genital samples from Ecuadorian men and women living in the city of Guayaquil. Genital samples included in daily diagnostic routine were analyzed by the 37 HPV GenoArray Diagnostic Kit (Hybribio® Ltd., Sheung Wan, Hong Kong). The relative frequency of detectable genotypes was determined. HPV relative frequency according to sample characteristics, including sex and age groups, was compared using c2 test. From the 800 samples (400 men and 400 women), 411 (51.38%) were positive for HPV DNA. The obtained frequency was higher among samples from men (253/400 or 63.25%) in comparison to samples from women (158/400 or 39.50%), with a p value <0.05. Samples from men showed a higher frequency of HPV genotypes 6, 16, 18 and 11, while among samples from women genotypes 39, 16, 6 and 58 were the most frequent. Considering male and female samples together, genotypes 6, 16, 39 and 11 presented the highest frequencies. HPV DNA was detected in half of the studied samples, with a higher frequency among samples from men. Genotype 39 was the most frequent among women, and ranked third when samples from men and women are analyzed together. |
format |
Article in Journal/Newspaper |
author |
Gustavo David García Muentes Marcia Adelaida Mendoza García Ramiro Israel Burgos Galárraga Kleber Ollague Cynthia Vargas Wachter Juan Carlos Ruiz Cabezas |
author_facet |
Gustavo David García Muentes Marcia Adelaida Mendoza García Ramiro Israel Burgos Galárraga Kleber Ollague Cynthia Vargas Wachter Juan Carlos Ruiz Cabezas |
author_sort |
Gustavo David García Muentes |
title |
Frequency and distribution of HPV genotypes in 800 genital samples of Ecuadorian men and women from the city of Guayaquil |
title_short |
Frequency and distribution of HPV genotypes in 800 genital samples of Ecuadorian men and women from the city of Guayaquil |
title_full |
Frequency and distribution of HPV genotypes in 800 genital samples of Ecuadorian men and women from the city of Guayaquil |
title_fullStr |
Frequency and distribution of HPV genotypes in 800 genital samples of Ecuadorian men and women from the city of Guayaquil |
title_full_unstemmed |
Frequency and distribution of HPV genotypes in 800 genital samples of Ecuadorian men and women from the city of Guayaquil |
title_sort |
frequency and distribution of hpv genotypes in 800 genital samples of ecuadorian men and women from the city of guayaquil |
publisher |
Universidade de São Paulo (USP) |
url |
https://doi.org/10.1590/s1678-9946201961041 https://doaj.org/article/1f71952dcb21429f8ff299296402c58e |
long_lat |
ENVELOPE(-59.767,-59.767,-62.449,-62.449) |
geographic |
Arctic Guayaquil |
geographic_facet |
Arctic Guayaquil |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 61 |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652019005000606&lng=en&tlng=en https://doaj.org/toc/1678-9946 1678-9946 doi:10.1590/s1678-9946201961041 https://doaj.org/article/1f71952dcb21429f8ff299296402c58e |
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https://doi.org/10.1590/s1678-9946201961041 |
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Revista do Instituto de Medicina Tropical de São Paulo |
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61 |
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