Mechanisms of virus resistance and antiviral activity of snake venoms
Viruses depend on cell metabolism for their own propagation. The need to foster an intimate relationship with the host has resulted in the development of various strategies designed to help virus escape from the defense mechanisms present in the host. Over millions of years, the unremitting battle b...
Published in: | Journal of Venomous Animals and Toxins including Tropical Diseases |
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ftdoajarticles:oai:doaj.org/article:1f7174af3a8749938e040b5623f96dc9 2023-05-15T15:06:29+02:00 Mechanisms of virus resistance and antiviral activity of snake venoms JVR Rivero FOF de Castro AS Stival MR Magalhães JR Carmo Filho IAH Pfrimer 2011-01-01T00:00:00Z https://doi.org/10.1590/S1678-91992011000400005 https://doaj.org/article/1f7174af3a8749938e040b5623f96dc9 EN eng SciELO http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000400005 https://doaj.org/toc/1678-9199 doi:10.1590/S1678-91992011000400005 1678-9199 https://doaj.org/article/1f7174af3a8749938e040b5623f96dc9 Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 17, Iss 4, Pp 387-393 (2011) snake venom viruses antiviral agents Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 article 2011 ftdoajarticles https://doi.org/10.1590/S1678-91992011000400005 2022-12-31T13:36:30Z Viruses depend on cell metabolism for their own propagation. The need to foster an intimate relationship with the host has resulted in the development of various strategies designed to help virus escape from the defense mechanisms present in the host. Over millions of years, the unremitting battle between pathogens and their hosts has led to changes in evolution of the immune system. Snake venoms are biological resources that have antiviral activity, hence substances of significant pharmacological value. The biodiversity in Brazil with respect to snakes is one of the richest on the planet; nevertheless, studies on the antiviral activity of venom from Brazilian snakes are scarce. The antiviral properties of snake venom appear as new promising therapeutic alternative against the defense mechanisms developed by viruses. In the current study, scientific papers published in recent years on the antiviral activity of venom from various species of snakes were reviewed. The objective of this review is to discuss the mechanisms of resistance developed by viruses and the components of snake venoms that present antiviral activity, particularly, enzymes, amino acids, peptides and proteins. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Venomous Animals and Toxins including Tropical Diseases 17 4 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
snake venom viruses antiviral agents Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
spellingShingle |
snake venom viruses antiviral agents Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 JVR Rivero FOF de Castro AS Stival MR Magalhães JR Carmo Filho IAH Pfrimer Mechanisms of virus resistance and antiviral activity of snake venoms |
topic_facet |
snake venom viruses antiviral agents Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
description |
Viruses depend on cell metabolism for their own propagation. The need to foster an intimate relationship with the host has resulted in the development of various strategies designed to help virus escape from the defense mechanisms present in the host. Over millions of years, the unremitting battle between pathogens and their hosts has led to changes in evolution of the immune system. Snake venoms are biological resources that have antiviral activity, hence substances of significant pharmacological value. The biodiversity in Brazil with respect to snakes is one of the richest on the planet; nevertheless, studies on the antiviral activity of venom from Brazilian snakes are scarce. The antiviral properties of snake venom appear as new promising therapeutic alternative against the defense mechanisms developed by viruses. In the current study, scientific papers published in recent years on the antiviral activity of venom from various species of snakes were reviewed. The objective of this review is to discuss the mechanisms of resistance developed by viruses and the components of snake venoms that present antiviral activity, particularly, enzymes, amino acids, peptides and proteins. |
format |
Article in Journal/Newspaper |
author |
JVR Rivero FOF de Castro AS Stival MR Magalhães JR Carmo Filho IAH Pfrimer |
author_facet |
JVR Rivero FOF de Castro AS Stival MR Magalhães JR Carmo Filho IAH Pfrimer |
author_sort |
JVR Rivero |
title |
Mechanisms of virus resistance and antiviral activity of snake venoms |
title_short |
Mechanisms of virus resistance and antiviral activity of snake venoms |
title_full |
Mechanisms of virus resistance and antiviral activity of snake venoms |
title_fullStr |
Mechanisms of virus resistance and antiviral activity of snake venoms |
title_full_unstemmed |
Mechanisms of virus resistance and antiviral activity of snake venoms |
title_sort |
mechanisms of virus resistance and antiviral activity of snake venoms |
publisher |
SciELO |
publishDate |
2011 |
url |
https://doi.org/10.1590/S1678-91992011000400005 https://doaj.org/article/1f7174af3a8749938e040b5623f96dc9 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 17, Iss 4, Pp 387-393 (2011) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000400005 https://doaj.org/toc/1678-9199 doi:10.1590/S1678-91992011000400005 1678-9199 https://doaj.org/article/1f7174af3a8749938e040b5623f96dc9 |
op_doi |
https://doi.org/10.1590/S1678-91992011000400005 |
container_title |
Journal of Venomous Animals and Toxins including Tropical Diseases |
container_volume |
17 |
container_issue |
4 |
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1766338083036332032 |