The Epidemiological Characteristics and Dynamic Transmission of Dengue in China, 2013.
BACKGROUND:There was a dengue epidemic in several regions of China in 2013. No study has explored the dynamics of dengue transmission between different geographical locations with dengue outbreaks in China. The purpose of the study is to analyze the epidemiological characteristics and to explore the...
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ftdoajarticles:oai:doaj.org/article:1f6b9782c39246d99322a410ea5015e1 2023-05-15T15:11:50+02:00 The Epidemiological Characteristics and Dynamic Transmission of Dengue in China, 2013. Shaowei Sang Shasha Wang Liang Lu Peng Bi Ming Lv Qiyong Liu 2016-11-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0005095 https://doaj.org/article/1f6b9782c39246d99322a410ea5015e1 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC5098828?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0005095 https://doaj.org/article/1f6b9782c39246d99322a410ea5015e1 PLoS Neglected Tropical Diseases, Vol 10, Iss 11, p e0005095 (2016) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2016 ftdoajarticles https://doi.org/10.1371/journal.pntd.0005095 2022-12-31T12:03:17Z BACKGROUND:There was a dengue epidemic in several regions of China in 2013. No study has explored the dynamics of dengue transmission between different geographical locations with dengue outbreaks in China. The purpose of the study is to analyze the epidemiological characteristics and to explore the dynamic transmission of dengue in China, 2013. METHODOLOGY AND PRINCIPAL FINDINGS:Records of dengue cases of 2013 were obtained from the China Notifiable Disease Surveillance System. Full E-gene sequences of dengue virus detected from the outbreak regions of China were download from GenBank. Geographical Information System and heatmaps were used to describe the epidemiological characteristics. Maximum Likelihood phylogenetic and Bayesian phylogeographic analyses were conducted to explore the dengue dynamic transmission. Yunnan Province and Guangdong Province had the highest imported cases in the 2013 epidemic. In the locations with local dengue transmission, most of imported cases occurred from June to November 2013 while local dengue cases developed from July to December, 2013. There were significant variations for the incidences of dengue, in terms of age distributions, among different geographic locations. However, gender differences were identified in Guangzhou, Foshan and Xishuangbanna. DENV 1-3 were detected in all locations with the disease outbreaks. Some genotypes were detected in more than one locations and more than one genotypes have been detected in several locations. The dengue viruses introduced to outbreak areas were predominantly from Southeast Asia. In Guangdong Province, the phylogeographical results indicated that dengue viruses of DENV 1 were transmitted to neighboring cities Foshan and Zhongshan from Guangzhou city, and then transmitted to Jiangmen city. The virus in DENV 3 was introduced to Guangzhou city, Guangdong Province from Xishuangbanna prefecture, Yunnan Province. CONCLUSIONS:Repeated dengue virus introductions from Southeast Asia and subsequent domestic dengue transmission within ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Zhongshan ENVELOPE(76.371,76.371,-69.373,-69.373) PLOS Neglected Tropical Diseases 10 11 e0005095 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Shaowei Sang Shasha Wang Liang Lu Peng Bi Ming Lv Qiyong Liu The Epidemiological Characteristics and Dynamic Transmission of Dengue in China, 2013. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND:There was a dengue epidemic in several regions of China in 2013. No study has explored the dynamics of dengue transmission between different geographical locations with dengue outbreaks in China. The purpose of the study is to analyze the epidemiological characteristics and to explore the dynamic transmission of dengue in China, 2013. METHODOLOGY AND PRINCIPAL FINDINGS:Records of dengue cases of 2013 were obtained from the China Notifiable Disease Surveillance System. Full E-gene sequences of dengue virus detected from the outbreak regions of China were download from GenBank. Geographical Information System and heatmaps were used to describe the epidemiological characteristics. Maximum Likelihood phylogenetic and Bayesian phylogeographic analyses were conducted to explore the dengue dynamic transmission. Yunnan Province and Guangdong Province had the highest imported cases in the 2013 epidemic. In the locations with local dengue transmission, most of imported cases occurred from June to November 2013 while local dengue cases developed from July to December, 2013. There were significant variations for the incidences of dengue, in terms of age distributions, among different geographic locations. However, gender differences were identified in Guangzhou, Foshan and Xishuangbanna. DENV 1-3 were detected in all locations with the disease outbreaks. Some genotypes were detected in more than one locations and more than one genotypes have been detected in several locations. The dengue viruses introduced to outbreak areas were predominantly from Southeast Asia. In Guangdong Province, the phylogeographical results indicated that dengue viruses of DENV 1 were transmitted to neighboring cities Foshan and Zhongshan from Guangzhou city, and then transmitted to Jiangmen city. The virus in DENV 3 was introduced to Guangzhou city, Guangdong Province from Xishuangbanna prefecture, Yunnan Province. CONCLUSIONS:Repeated dengue virus introductions from Southeast Asia and subsequent domestic dengue transmission within ... |
format |
Article in Journal/Newspaper |
author |
Shaowei Sang Shasha Wang Liang Lu Peng Bi Ming Lv Qiyong Liu |
author_facet |
Shaowei Sang Shasha Wang Liang Lu Peng Bi Ming Lv Qiyong Liu |
author_sort |
Shaowei Sang |
title |
The Epidemiological Characteristics and Dynamic Transmission of Dengue in China, 2013. |
title_short |
The Epidemiological Characteristics and Dynamic Transmission of Dengue in China, 2013. |
title_full |
The Epidemiological Characteristics and Dynamic Transmission of Dengue in China, 2013. |
title_fullStr |
The Epidemiological Characteristics and Dynamic Transmission of Dengue in China, 2013. |
title_full_unstemmed |
The Epidemiological Characteristics and Dynamic Transmission of Dengue in China, 2013. |
title_sort |
epidemiological characteristics and dynamic transmission of dengue in china, 2013. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2016 |
url |
https://doi.org/10.1371/journal.pntd.0005095 https://doaj.org/article/1f6b9782c39246d99322a410ea5015e1 |
long_lat |
ENVELOPE(76.371,76.371,-69.373,-69.373) |
geographic |
Arctic Zhongshan |
geographic_facet |
Arctic Zhongshan |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 10, Iss 11, p e0005095 (2016) |
op_relation |
http://europepmc.org/articles/PMC5098828?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0005095 https://doaj.org/article/1f6b9782c39246d99322a410ea5015e1 |
op_doi |
https://doi.org/10.1371/journal.pntd.0005095 |
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PLOS Neglected Tropical Diseases |
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10 |
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11 |
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e0005095 |
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