Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar
Thirty cases of human kala-azar were diagnosed by iliac crest biopsy and myeloculture. Histological analysis of 12 patients showed diffuse thickening of reticulin fibers. To the best of our knowledge, this is the third report describing secondary bone marrow fibrosis (myelofibrosis-like) associated...
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Sociedade Brasileira de Medicina Tropical (SBMT)
2000
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ftdoajarticles:oai:doaj.org/article:1f60b1ed6b494b8897160de611ac9137 2023-05-15T15:00:11+02:00 Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar Rocha Filho Francisco Dário Ferreira Francisco Valdeci de Almeida Mendes Flávia de Oliveira Ferreira Fernanda Nogueira Holanda Karbage Alexandre Alencar Marília Lage Costa Danielle 2000-01-01T00:00:00Z https://doaj.org/article/1f60b1ed6b494b8897160de611ac9137 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822000000400005 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/1f60b1ed6b494b8897160de611ac9137 Revista da Sociedade Brasileira de Medicina Tropical, Vol 33, Iss 4, Pp 363-366 (2000) Human kala-azar Myelofibrosis Bone marrow biopsy Arctic medicine. Tropical medicine RC955-962 article 2000 ftdoajarticles 2022-12-30T21:28:00Z Thirty cases of human kala-azar were diagnosed by iliac crest biopsy and myeloculture. Histological analysis of 12 patients showed diffuse thickening of reticulin fibers. To the best of our knowledge, this is the third report describing secondary bone marrow fibrosis (myelofibrosis-like) associated with kala-azar. Patients with positive bone marrow fibrosis (pbmf = 12) were compared to patients without detectable bone marrow fibrosis (wbmf = 18). There were no significant differences in clinical and blood parameters following treatment. All patients showed regression of hepatosplenomegaly.Our findings suggest that associated bone marrow fibrosis is transient and did not interfere in the evolution of treated patients. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Azar ENVELOPE(-63.733,-63.733,-64.983,-64.983) |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Human kala-azar Myelofibrosis Bone marrow biopsy Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Human kala-azar Myelofibrosis Bone marrow biopsy Arctic medicine. Tropical medicine RC955-962 Rocha Filho Francisco Dário Ferreira Francisco Valdeci de Almeida Mendes Flávia de Oliveira Ferreira Fernanda Nogueira Holanda Karbage Alexandre Alencar Marília Lage Costa Danielle Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar |
topic_facet |
Human kala-azar Myelofibrosis Bone marrow biopsy Arctic medicine. Tropical medicine RC955-962 |
description |
Thirty cases of human kala-azar were diagnosed by iliac crest biopsy and myeloculture. Histological analysis of 12 patients showed diffuse thickening of reticulin fibers. To the best of our knowledge, this is the third report describing secondary bone marrow fibrosis (myelofibrosis-like) associated with kala-azar. Patients with positive bone marrow fibrosis (pbmf = 12) were compared to patients without detectable bone marrow fibrosis (wbmf = 18). There were no significant differences in clinical and blood parameters following treatment. All patients showed regression of hepatosplenomegaly.Our findings suggest that associated bone marrow fibrosis is transient and did not interfere in the evolution of treated patients. |
format |
Article in Journal/Newspaper |
author |
Rocha Filho Francisco Dário Ferreira Francisco Valdeci de Almeida Mendes Flávia de Oliveira Ferreira Fernanda Nogueira Holanda Karbage Alexandre Alencar Marília Lage Costa Danielle |
author_facet |
Rocha Filho Francisco Dário Ferreira Francisco Valdeci de Almeida Mendes Flávia de Oliveira Ferreira Fernanda Nogueira Holanda Karbage Alexandre Alencar Marília Lage Costa Danielle |
author_sort |
Rocha Filho Francisco Dário |
title |
Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar |
title_short |
Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar |
title_full |
Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar |
title_fullStr |
Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar |
title_full_unstemmed |
Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar |
title_sort |
bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2000 |
url |
https://doaj.org/article/1f60b1ed6b494b8897160de611ac9137 |
long_lat |
ENVELOPE(-63.733,-63.733,-64.983,-64.983) |
geographic |
Arctic Azar |
geographic_facet |
Arctic Azar |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 33, Iss 4, Pp 363-366 (2000) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822000000400005 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/1f60b1ed6b494b8897160de611ac9137 |
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1766332290264203264 |