Risk factors for malaria infection prevalence and household vector density between mass distribution campaigns of long-lasting insecticidal nets in North-western Tanzania
Abstract Background Long-lasting insecticidal nets (LLINs) are the most widely deployed vector control intervention in sub-Saharan Africa to prevent malaria. Recent reports indicate selection of pyrethroid insecticide resistance is widespread in mosquito vectors. This paper explores risk factors ass...
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ftdoajarticles:oai:doaj.org/article:1f2bbcce378444489c26c510ee67ff92 2023-05-15T15:16:39+02:00 Risk factors for malaria infection prevalence and household vector density between mass distribution campaigns of long-lasting insecticidal nets in North-western Tanzania Jacklin F. Mosha Eliud Lukole J. Derek Charlwood Alexandra Wright Mark Rowland Olivia Bullock Alphaxard Manjurano William Kisinza Franklin W. Mosha Immo Kleinschmidt Natacha Protopopoff 2020-08-01T00:00:00Z https://doi.org/10.1186/s12936-020-03369-4 https://doaj.org/article/1f2bbcce378444489c26c510ee67ff92 EN eng BMC http://link.springer.com/article/10.1186/s12936-020-03369-4 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-020-03369-4 1475-2875 https://doaj.org/article/1f2bbcce378444489c26c510ee67ff92 Malaria Journal, Vol 19, Iss 1, Pp 1-11 (2020) Malaria Llins Effectiveness Vectors Tanzania Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2020 ftdoajarticles https://doi.org/10.1186/s12936-020-03369-4 2023-01-08T01:30:43Z Abstract Background Long-lasting insecticidal nets (LLINs) are the most widely deployed vector control intervention in sub-Saharan Africa to prevent malaria. Recent reports indicate selection of pyrethroid insecticide resistance is widespread in mosquito vectors. This paper explores risk factors associated with malaria infection prevalence and vector density between mass distribution campaigns, changes in net coverage, and loss of protection in an area of high pyrethroid resistance in Northwest Tanzania. Methods A cross sectional malaria survey of 3456 children was undertaken in 2014 in Muleba district, Kagera region west of Lake Victoria. Vector density was assessed using indoor light traps and outdoor tent traps. Anophelines were identified to species using PCR and tested for Plasmodium falciparum circumsporozoite protein. Logistic regression was used to identify household and environmental factors associated with malaria infection and regression binomial negative for vector density. Results LLIN use was 27.7%. Only 16.9% of households had sufficient nets to cover all sleeping places. Malaria infection was independently associated with access to LLINs (OR: 0.57; 95% CI 0.34–0.98). LLINs less than 2 years old were slightly more protective than older LLINs (53 vs 65% prevalence of infection); however, there was no evidence that LLINs in good condition (hole index < 65) were more protective than LLINs, which were more holed. Other risk factors for malaria infection were age, group, altitude and house construction quality. Independent risk factors for vector density were consistent with malaria outcomes and included altitude, wind, livestock, house quality, open eaves and LLIN usage. Indoor collections comprised 4.6% Anopheles funestus and 95.4% Anopheles gambiae of which 4.5% were Anopheles arabiensis and 93.5% were Anopheles gambiae sensu stricto. Conclusion Three years after the mass distribution campaign and despite top-ups, LLIN usage had declined considerably. While children living in households with ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 19 1 |
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English |
topic |
Malaria Llins Effectiveness Vectors Tanzania Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Malaria Llins Effectiveness Vectors Tanzania Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Jacklin F. Mosha Eliud Lukole J. Derek Charlwood Alexandra Wright Mark Rowland Olivia Bullock Alphaxard Manjurano William Kisinza Franklin W. Mosha Immo Kleinschmidt Natacha Protopopoff Risk factors for malaria infection prevalence and household vector density between mass distribution campaigns of long-lasting insecticidal nets in North-western Tanzania |
topic_facet |
Malaria Llins Effectiveness Vectors Tanzania Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Long-lasting insecticidal nets (LLINs) are the most widely deployed vector control intervention in sub-Saharan Africa to prevent malaria. Recent reports indicate selection of pyrethroid insecticide resistance is widespread in mosquito vectors. This paper explores risk factors associated with malaria infection prevalence and vector density between mass distribution campaigns, changes in net coverage, and loss of protection in an area of high pyrethroid resistance in Northwest Tanzania. Methods A cross sectional malaria survey of 3456 children was undertaken in 2014 in Muleba district, Kagera region west of Lake Victoria. Vector density was assessed using indoor light traps and outdoor tent traps. Anophelines were identified to species using PCR and tested for Plasmodium falciparum circumsporozoite protein. Logistic regression was used to identify household and environmental factors associated with malaria infection and regression binomial negative for vector density. Results LLIN use was 27.7%. Only 16.9% of households had sufficient nets to cover all sleeping places. Malaria infection was independently associated with access to LLINs (OR: 0.57; 95% CI 0.34–0.98). LLINs less than 2 years old were slightly more protective than older LLINs (53 vs 65% prevalence of infection); however, there was no evidence that LLINs in good condition (hole index < 65) were more protective than LLINs, which were more holed. Other risk factors for malaria infection were age, group, altitude and house construction quality. Independent risk factors for vector density were consistent with malaria outcomes and included altitude, wind, livestock, house quality, open eaves and LLIN usage. Indoor collections comprised 4.6% Anopheles funestus and 95.4% Anopheles gambiae of which 4.5% were Anopheles arabiensis and 93.5% were Anopheles gambiae sensu stricto. Conclusion Three years after the mass distribution campaign and despite top-ups, LLIN usage had declined considerably. While children living in households with ... |
format |
Article in Journal/Newspaper |
author |
Jacklin F. Mosha Eliud Lukole J. Derek Charlwood Alexandra Wright Mark Rowland Olivia Bullock Alphaxard Manjurano William Kisinza Franklin W. Mosha Immo Kleinschmidt Natacha Protopopoff |
author_facet |
Jacklin F. Mosha Eliud Lukole J. Derek Charlwood Alexandra Wright Mark Rowland Olivia Bullock Alphaxard Manjurano William Kisinza Franklin W. Mosha Immo Kleinschmidt Natacha Protopopoff |
author_sort |
Jacklin F. Mosha |
title |
Risk factors for malaria infection prevalence and household vector density between mass distribution campaigns of long-lasting insecticidal nets in North-western Tanzania |
title_short |
Risk factors for malaria infection prevalence and household vector density between mass distribution campaigns of long-lasting insecticidal nets in North-western Tanzania |
title_full |
Risk factors for malaria infection prevalence and household vector density between mass distribution campaigns of long-lasting insecticidal nets in North-western Tanzania |
title_fullStr |
Risk factors for malaria infection prevalence and household vector density between mass distribution campaigns of long-lasting insecticidal nets in North-western Tanzania |
title_full_unstemmed |
Risk factors for malaria infection prevalence and household vector density between mass distribution campaigns of long-lasting insecticidal nets in North-western Tanzania |
title_sort |
risk factors for malaria infection prevalence and household vector density between mass distribution campaigns of long-lasting insecticidal nets in north-western tanzania |
publisher |
BMC |
publishDate |
2020 |
url |
https://doi.org/10.1186/s12936-020-03369-4 https://doaj.org/article/1f2bbcce378444489c26c510ee67ff92 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 19, Iss 1, Pp 1-11 (2020) |
op_relation |
http://link.springer.com/article/10.1186/s12936-020-03369-4 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-020-03369-4 1475-2875 https://doaj.org/article/1f2bbcce378444489c26c510ee67ff92 |
op_doi |
https://doi.org/10.1186/s12936-020-03369-4 |
container_title |
Malaria Journal |
container_volume |
19 |
container_issue |
1 |
_version_ |
1766346946189983744 |