Methodological approaches for analysing data from therapeutic efficacy studies

• Published in: Malaria Journal
• Main Authors: Solange Whegang Youdom, Leonardo K. Basco
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2021
• Subjects: Plasmodium falciparum; Drug resistance; Artemisinin; Ordinal outcome; Multiple comparison; Network meta-analysis; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic; Meier
• Online Access: https://doi.org/10.1186/s12936-021-03768-1; https://doaj.org/article/1f2841539cc6438db138c9b5819ccd59

Abstract Several anti-malarial drugs have been evaluated in randomized clinical trials to treat acute uncomplicated Plasmodium falciparum malaria. The outcome of anti-malarial drug efficacy studies is classified into one of four possible outcomes defined by the World Health Organization: adequate cl...