In vitro antibacterial activity and major bioactive components of Cinnamomum verum essential oils against cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus
Objective: To evaluate the antibacterial activity of Cinnamomum verum (C. verum) from 32 different essential oils against cariogenic bacteria, Streptococcus mutans (S. mutans) and Streptococcus sobrinus (S. sobrinus). Methods: The antibacterial activities of each essential oil were individually inve...
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Wolters Kluwer Medknow Publications
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ftdoajarticles:oai:doaj.org/article:1eae83cb1a564a089e1460df5cd23b29 2023-05-15T15:10:55+02:00 In vitro antibacterial activity and major bioactive components of Cinnamomum verum essential oils against cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus Okhee Choi Su Kyung Cho Junheon Kim Chung Gyoo Park Jinwoo Kim 2016-04-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2016.01.007 https://doaj.org/article/1eae83cb1a564a089e1460df5cd23b29 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169115308844 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2016.01.007 https://doaj.org/article/1eae83cb1a564a089e1460df5cd23b29 Asian Pacific Journal of Tropical Biomedicine, Vol 6, Iss 4, Pp 308-314 (2016) Streptococcus mutans Streptococcus sobrinus Cariogenic bacteria Essential oil Antibacterial activity Cinnamaldehyde Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2016 ftdoajarticles https://doi.org/10.1016/j.apjtb.2016.01.007 2022-12-31T01:51:37Z Objective: To evaluate the antibacterial activity of Cinnamomum verum (C. verum) from 32 different essential oils against cariogenic bacteria, Streptococcus mutans (S. mutans) and Streptococcus sobrinus (S. sobrinus). Methods: The antibacterial activities of each essential oil were individually investigated against S. mutans and S. sobrinus. The essential oil of C. verum was selected for further evaluation against S. mutans and S. sobrinus. Gas chromatography mass spectrometry was used to determine the major constituents of C. verum essential oil. In addition, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration of the most effective constituent was investigated. Results: The essential oil from C. verum exhibited the greatest antibacterial activity. Gas chromatography mass spectrometry analysis revealed that the major components of C. verum essential oil were cinnamaldehyde (56.3%), cinnamyl acetate (7.1%) and β-phellandrene (6.3%). The MIC of cinnamaldehyde was measured using broth dilution assays. The MIC of cinnamaldehyde was 0.02% (v/v) against both bacterial strains tested. The minimum bactericidal concentration of cinnamaldehyde against S. mutans and S. sobrinus were 0.2% and 0.1% (v/v), respectively. Conclusions: The essential oil of C. verum and its major component cinnamaldehyde possessed considerable in vitro antibacterial activities against cariogenic bacteria, S. mutans and S. sobrinus strains. These results showed that the essential oil of C. verum and its bioactive component, cinnamaldehyde, have potential for application as natural agents for the prevention and treatment of dental caries. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 6 4 308 314 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Streptococcus mutans Streptococcus sobrinus Cariogenic bacteria Essential oil Antibacterial activity Cinnamaldehyde Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Streptococcus mutans Streptococcus sobrinus Cariogenic bacteria Essential oil Antibacterial activity Cinnamaldehyde Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Okhee Choi Su Kyung Cho Junheon Kim Chung Gyoo Park Jinwoo Kim In vitro antibacterial activity and major bioactive components of Cinnamomum verum essential oils against cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus |
topic_facet |
Streptococcus mutans Streptococcus sobrinus Cariogenic bacteria Essential oil Antibacterial activity Cinnamaldehyde Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To evaluate the antibacterial activity of Cinnamomum verum (C. verum) from 32 different essential oils against cariogenic bacteria, Streptococcus mutans (S. mutans) and Streptococcus sobrinus (S. sobrinus). Methods: The antibacterial activities of each essential oil were individually investigated against S. mutans and S. sobrinus. The essential oil of C. verum was selected for further evaluation against S. mutans and S. sobrinus. Gas chromatography mass spectrometry was used to determine the major constituents of C. verum essential oil. In addition, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration of the most effective constituent was investigated. Results: The essential oil from C. verum exhibited the greatest antibacterial activity. Gas chromatography mass spectrometry analysis revealed that the major components of C. verum essential oil were cinnamaldehyde (56.3%), cinnamyl acetate (7.1%) and β-phellandrene (6.3%). The MIC of cinnamaldehyde was measured using broth dilution assays. The MIC of cinnamaldehyde was 0.02% (v/v) against both bacterial strains tested. The minimum bactericidal concentration of cinnamaldehyde against S. mutans and S. sobrinus were 0.2% and 0.1% (v/v), respectively. Conclusions: The essential oil of C. verum and its major component cinnamaldehyde possessed considerable in vitro antibacterial activities against cariogenic bacteria, S. mutans and S. sobrinus strains. These results showed that the essential oil of C. verum and its bioactive component, cinnamaldehyde, have potential for application as natural agents for the prevention and treatment of dental caries. |
format |
Article in Journal/Newspaper |
author |
Okhee Choi Su Kyung Cho Junheon Kim Chung Gyoo Park Jinwoo Kim |
author_facet |
Okhee Choi Su Kyung Cho Junheon Kim Chung Gyoo Park Jinwoo Kim |
author_sort |
Okhee Choi |
title |
In vitro antibacterial activity and major bioactive components of Cinnamomum verum essential oils against cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus |
title_short |
In vitro antibacterial activity and major bioactive components of Cinnamomum verum essential oils against cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus |
title_full |
In vitro antibacterial activity and major bioactive components of Cinnamomum verum essential oils against cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus |
title_fullStr |
In vitro antibacterial activity and major bioactive components of Cinnamomum verum essential oils against cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus |
title_full_unstemmed |
In vitro antibacterial activity and major bioactive components of Cinnamomum verum essential oils against cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus |
title_sort |
in vitro antibacterial activity and major bioactive components of cinnamomum verum essential oils against cariogenic bacteria, streptococcus mutans and streptococcus sobrinus |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2016 |
url |
https://doi.org/10.1016/j.apjtb.2016.01.007 https://doaj.org/article/1eae83cb1a564a089e1460df5cd23b29 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 6, Iss 4, Pp 308-314 (2016) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169115308844 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2016.01.007 https://doaj.org/article/1eae83cb1a564a089e1460df5cd23b29 |
op_doi |
https://doi.org/10.1016/j.apjtb.2016.01.007 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
6 |
container_issue |
4 |
container_start_page |
308 |
op_container_end_page |
314 |
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