Revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools
Different aspects of hepatosplenic schistosomiasis are revisited here. Manson's schistosomiasis causes periportal fibrosis and portal hypertension in approximately 6% of infected subjects, usually with preservation of their hepatic function. The assessment of liver involvement is of major impor...
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ftdoajarticles:oai:doaj.org/article:1e9c76856f834212b3d9ffed780ecbd9 2023-05-15T15:08:14+02:00 Revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools José Roberto Lambertucci 2014-05-01T00:00:00Z https://doi.org/10.1590/0037-8682-0186-2013 https://doaj.org/article/1e9c76856f834212b3d9ffed780ecbd9 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000200130&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0186-2013 https://doaj.org/article/1e9c76856f834212b3d9ffed780ecbd9 Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 2, Pp 130-136 (2014) Hepatosplenic schistosomiasis Ultrasound Magnetic resonance imaging Thrombocytopenia Manson's schistosomiasis Arctic medicine. Tropical medicine RC955-962 article 2014 ftdoajarticles https://doi.org/10.1590/0037-8682-0186-2013 2022-12-31T03:01:13Z Different aspects of hepatosplenic schistosomiasis are revisited here. Manson's schistosomiasis causes periportal fibrosis and portal hypertension in approximately 6% of infected subjects, usually with preservation of their hepatic function. The assessment of liver involvement is of major importance in determining the prognosis and risk of complications from schistosomiasis, such as upper digestive bleeding secondary to variceal rupture. For many years, the diagnosis of hepatosplenic schistosomiasis and liver fibrosis was made by abdominal palpation and the finding of liver and/or spleen enlargement. However, there is no consensus regarding the clinical parameters of the liver and spleen to be considered in this physical evaluation. For the last three decades, abdominal ultrasound (US) has become the best imaging technique to evaluate liver fibrosis caused by schistosomiasis mansoni. However, US is a subjective procedure and is therefore examiner-dependent. Magnetic resonance imaging (MRI) findings have provided valuable information in addition to ultrasound and clinical examination. The combination of a comprehensive history and physical examination, basic laboratory tests (a stool examination for Schistosoma mansoni eggs and a blood cell count), biomarkers for liver fibrosis/portal hypertension and imaging methods seem to offer the best approach for evaluating patients with this disease. In situations where research is involved or in patients with severe disease, MRI may be considered. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 47 2 130 136 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Hepatosplenic schistosomiasis Ultrasound Magnetic resonance imaging Thrombocytopenia Manson's schistosomiasis Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Hepatosplenic schistosomiasis Ultrasound Magnetic resonance imaging Thrombocytopenia Manson's schistosomiasis Arctic medicine. Tropical medicine RC955-962 José Roberto Lambertucci Revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools |
topic_facet |
Hepatosplenic schistosomiasis Ultrasound Magnetic resonance imaging Thrombocytopenia Manson's schistosomiasis Arctic medicine. Tropical medicine RC955-962 |
description |
Different aspects of hepatosplenic schistosomiasis are revisited here. Manson's schistosomiasis causes periportal fibrosis and portal hypertension in approximately 6% of infected subjects, usually with preservation of their hepatic function. The assessment of liver involvement is of major importance in determining the prognosis and risk of complications from schistosomiasis, such as upper digestive bleeding secondary to variceal rupture. For many years, the diagnosis of hepatosplenic schistosomiasis and liver fibrosis was made by abdominal palpation and the finding of liver and/or spleen enlargement. However, there is no consensus regarding the clinical parameters of the liver and spleen to be considered in this physical evaluation. For the last three decades, abdominal ultrasound (US) has become the best imaging technique to evaluate liver fibrosis caused by schistosomiasis mansoni. However, US is a subjective procedure and is therefore examiner-dependent. Magnetic resonance imaging (MRI) findings have provided valuable information in addition to ultrasound and clinical examination. The combination of a comprehensive history and physical examination, basic laboratory tests (a stool examination for Schistosoma mansoni eggs and a blood cell count), biomarkers for liver fibrosis/portal hypertension and imaging methods seem to offer the best approach for evaluating patients with this disease. In situations where research is involved or in patients with severe disease, MRI may be considered. |
format |
Article in Journal/Newspaper |
author |
José Roberto Lambertucci |
author_facet |
José Roberto Lambertucci |
author_sort |
José Roberto Lambertucci |
title |
Revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools |
title_short |
Revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools |
title_full |
Revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools |
title_fullStr |
Revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools |
title_full_unstemmed |
Revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools |
title_sort |
revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2014 |
url |
https://doi.org/10.1590/0037-8682-0186-2013 https://doaj.org/article/1e9c76856f834212b3d9ffed780ecbd9 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 2, Pp 130-136 (2014) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000200130&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0186-2013 https://doaj.org/article/1e9c76856f834212b3d9ffed780ecbd9 |
op_doi |
https://doi.org/10.1590/0037-8682-0186-2013 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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47 |
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