Unravelling the impact of insecticide-treated bed nets on childhood malaria in Malawi
Abstract Background To achieve malaria elimination it is essential to understand the impact of insecticide-treated net (ITNs) programmes. Here, the impact of ITN access and use on malaria prevalence in children in Malawi was investigated using Malaria Indicator Survey (MIS) data. Methods MIS data fr...
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ftdoajarticles:oai:doaj.org/article:1e2f441870f642abb1eb113fbf0783bc 2023-05-15T15:15:57+02:00 Unravelling the impact of insecticide-treated bed nets on childhood malaria in Malawi Julie-Anne A. Tangena Donnie Mategula Luigi Sedda Peter M. Atkinson 2023-01-01T00:00:00Z https://doi.org/10.1186/s12936-023-04448-y https://doaj.org/article/1e2f441870f642abb1eb113fbf0783bc EN eng BMC https://doi.org/10.1186/s12936-023-04448-y https://doaj.org/toc/1475-2875 doi:10.1186/s12936-023-04448-y 1475-2875 https://doaj.org/article/1e2f441870f642abb1eb113fbf0783bc Malaria Journal, Vol 22, Iss 1, Pp 1-12 (2023) Malaria indicator survey Malawi Insecticide-treated bed net Bed net use Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2023 ftdoajarticles https://doi.org/10.1186/s12936-023-04448-y 2023-01-22T01:41:59Z Abstract Background To achieve malaria elimination it is essential to understand the impact of insecticide-treated net (ITNs) programmes. Here, the impact of ITN access and use on malaria prevalence in children in Malawi was investigated using Malaria Indicator Survey (MIS) data. Methods MIS data from 2012, 2014 and 2017 were used to investigate the relationship between malaria prevalence in children (6–59 months) and ITN use. Generalized linear modelling (GLM), geostatistical mixed regression modelling and non-stationary GLM were undertaken to evaluate trends, spatial patterns and local dynamics, respectively. Results Malaria prevalence in Malawi was 27.1% (95% CI 23.1–31.2%) in 2012 and similar in both 2014 (32.1%, 95% CI 25.5–38.7) and 2017 (23.9%, 95% CI 20.3–27.4%). ITN coverage and use increased during the same time period, with household ITN access growing from 19.0% (95% CI 15.6–22.3%) of households with at least 1 ITN for every 2 people sleeping in the house the night before to 41.7% (95% CI 39.1–44.4%) and ITN use from 41.1% (95% CI 37.3–44.9%) of the population sleeping under an ITN the previous night to 57.4% (95% CI 55.0–59.9%). Both the geostatistical and non-stationary GLM regression models showed child malaria prevalence had a negative association with ITN population access and a positive association with ITN use although affected by large uncertainties. The non-stationary GLM highlighted the spatital heterogeneity in the relationship between childhood malaria and ITN dynamics across the country. Conclusion Malaria prevalence in children under five had a negative association with ITN population access and a positive association with ITN use, with spatial heterogeneity in these relationships across Malawi. This study presents an important modelling approach that allows malaria control programmes to spatially disentangle the impact of interventions on malaria cases. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 22 1 |
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Malaria indicator survey Malawi Insecticide-treated bed net Bed net use Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Malaria indicator survey Malawi Insecticide-treated bed net Bed net use Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Julie-Anne A. Tangena Donnie Mategula Luigi Sedda Peter M. Atkinson Unravelling the impact of insecticide-treated bed nets on childhood malaria in Malawi |
topic_facet |
Malaria indicator survey Malawi Insecticide-treated bed net Bed net use Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background To achieve malaria elimination it is essential to understand the impact of insecticide-treated net (ITNs) programmes. Here, the impact of ITN access and use on malaria prevalence in children in Malawi was investigated using Malaria Indicator Survey (MIS) data. Methods MIS data from 2012, 2014 and 2017 were used to investigate the relationship between malaria prevalence in children (6–59 months) and ITN use. Generalized linear modelling (GLM), geostatistical mixed regression modelling and non-stationary GLM were undertaken to evaluate trends, spatial patterns and local dynamics, respectively. Results Malaria prevalence in Malawi was 27.1% (95% CI 23.1–31.2%) in 2012 and similar in both 2014 (32.1%, 95% CI 25.5–38.7) and 2017 (23.9%, 95% CI 20.3–27.4%). ITN coverage and use increased during the same time period, with household ITN access growing from 19.0% (95% CI 15.6–22.3%) of households with at least 1 ITN for every 2 people sleeping in the house the night before to 41.7% (95% CI 39.1–44.4%) and ITN use from 41.1% (95% CI 37.3–44.9%) of the population sleeping under an ITN the previous night to 57.4% (95% CI 55.0–59.9%). Both the geostatistical and non-stationary GLM regression models showed child malaria prevalence had a negative association with ITN population access and a positive association with ITN use although affected by large uncertainties. The non-stationary GLM highlighted the spatital heterogeneity in the relationship between childhood malaria and ITN dynamics across the country. Conclusion Malaria prevalence in children under five had a negative association with ITN population access and a positive association with ITN use, with spatial heterogeneity in these relationships across Malawi. This study presents an important modelling approach that allows malaria control programmes to spatially disentangle the impact of interventions on malaria cases. |
format |
Article in Journal/Newspaper |
author |
Julie-Anne A. Tangena Donnie Mategula Luigi Sedda Peter M. Atkinson |
author_facet |
Julie-Anne A. Tangena Donnie Mategula Luigi Sedda Peter M. Atkinson |
author_sort |
Julie-Anne A. Tangena |
title |
Unravelling the impact of insecticide-treated bed nets on childhood malaria in Malawi |
title_short |
Unravelling the impact of insecticide-treated bed nets on childhood malaria in Malawi |
title_full |
Unravelling the impact of insecticide-treated bed nets on childhood malaria in Malawi |
title_fullStr |
Unravelling the impact of insecticide-treated bed nets on childhood malaria in Malawi |
title_full_unstemmed |
Unravelling the impact of insecticide-treated bed nets on childhood malaria in Malawi |
title_sort |
unravelling the impact of insecticide-treated bed nets on childhood malaria in malawi |
publisher |
BMC |
publishDate |
2023 |
url |
https://doi.org/10.1186/s12936-023-04448-y https://doaj.org/article/1e2f441870f642abb1eb113fbf0783bc |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 22, Iss 1, Pp 1-12 (2023) |
op_relation |
https://doi.org/10.1186/s12936-023-04448-y https://doaj.org/toc/1475-2875 doi:10.1186/s12936-023-04448-y 1475-2875 https://doaj.org/article/1e2f441870f642abb1eb113fbf0783bc |
op_doi |
https://doi.org/10.1186/s12936-023-04448-y |
container_title |
Malaria Journal |
container_volume |
22 |
container_issue |
1 |
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1766346272059424768 |