High endemicity of Clonorchis sinensis infection in Binyang County, southern China.
High-intensity clonorchiasis infection is associated with serious outcomes, including cancer. Understanding the infection intensity of Clonorchis sinensis and its risk factors in local endemic regions could facilitate effective control measures. In a county located in a highly endemic area in Guangx...
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ftdoajarticles:oai:doaj.org/article:1dcf3f1a849a40e6bf37615cb09cc2ff 2023-05-15T15:16:18+02:00 High endemicity of Clonorchis sinensis infection in Binyang County, southern China. Junling Sun Hualei Xin Zhihua Jiang Menbao Qian Kaixia Duan Yingdan Chen Shizhu Li Wei Li Shiyong Huang Xiaoqin Gan Yichao Yang Zhongjie Li 2020-08-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0008540 https://doaj.org/article/1dcf3f1a849a40e6bf37615cb09cc2ff EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0008540 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008540 https://doaj.org/article/1dcf3f1a849a40e6bf37615cb09cc2ff PLoS Neglected Tropical Diseases, Vol 14, Iss 8, p e0008540 (2020) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2020 ftdoajarticles https://doi.org/10.1371/journal.pntd.0008540 2022-12-31T07:48:36Z High-intensity clonorchiasis infection is associated with serious outcomes, including cancer. Understanding the infection intensity of Clonorchis sinensis and its risk factors in local endemic regions could facilitate effective control measures. In a county located in a highly endemic area in Guangxi Province, P. R. China, local residents were randomly enrolled in the study; helminth egg examinations were performed with the Kato-Katz method, and the intensity of infection was identified as mild, moderate or heavy. Knowledge, attitudes, and high-risk behaviours were investigated among those infected with Clonorchis sinensis. A total of 2521 local residents participated in this study, and the Clonorchis sinensis-positive proportion was 28.9% (728 persons). Among the infected persons, the percentages of mild, moderate and heavy infections were 66.2%, 28.4% and 5.4%, respectively. Males experienced a higher proportion of moderate and heavy infections (37.5%) than females (18.1%) (p<0.05). The highest infection proportion among the different levels of infection intensity was identified among persons aged 30-59 years (15.7% for moderate and heavy infections). Among the 509 persons who reported eating raw fish, 302 persons (59.3%) had eaten raw fresh fish for more than 10 years, and 131 (25.7%) persons ate raw fish ≥12 times a year. Multivariate logistic regression revealed that eating raw fish 12-50 times in the last year (adjusted odds ratio [aOR] = 1.74, 95%CI: 1.09-2.80) and eating raw fish >50 times in the last year (aOR = 2.89, 95%CI: 1.20-7.50) were risk factors for high-intensity infections (moderate and heavy). The overall infection proportion was high in the study area, with a large group of residents experiencing high-intensity infections. High frequency of raw fish consumption was associated with high-intensity infections. Intervention strategies targeting people with a high frequency of raw fish consumption should be implemented to reduce the probability of severe consequences. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 14 8 e0008540 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Junling Sun Hualei Xin Zhihua Jiang Menbao Qian Kaixia Duan Yingdan Chen Shizhu Li Wei Li Shiyong Huang Xiaoqin Gan Yichao Yang Zhongjie Li High endemicity of Clonorchis sinensis infection in Binyang County, southern China. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
High-intensity clonorchiasis infection is associated with serious outcomes, including cancer. Understanding the infection intensity of Clonorchis sinensis and its risk factors in local endemic regions could facilitate effective control measures. In a county located in a highly endemic area in Guangxi Province, P. R. China, local residents were randomly enrolled in the study; helminth egg examinations were performed with the Kato-Katz method, and the intensity of infection was identified as mild, moderate or heavy. Knowledge, attitudes, and high-risk behaviours were investigated among those infected with Clonorchis sinensis. A total of 2521 local residents participated in this study, and the Clonorchis sinensis-positive proportion was 28.9% (728 persons). Among the infected persons, the percentages of mild, moderate and heavy infections were 66.2%, 28.4% and 5.4%, respectively. Males experienced a higher proportion of moderate and heavy infections (37.5%) than females (18.1%) (p<0.05). The highest infection proportion among the different levels of infection intensity was identified among persons aged 30-59 years (15.7% for moderate and heavy infections). Among the 509 persons who reported eating raw fish, 302 persons (59.3%) had eaten raw fresh fish for more than 10 years, and 131 (25.7%) persons ate raw fish ≥12 times a year. Multivariate logistic regression revealed that eating raw fish 12-50 times in the last year (adjusted odds ratio [aOR] = 1.74, 95%CI: 1.09-2.80) and eating raw fish >50 times in the last year (aOR = 2.89, 95%CI: 1.20-7.50) were risk factors for high-intensity infections (moderate and heavy). The overall infection proportion was high in the study area, with a large group of residents experiencing high-intensity infections. High frequency of raw fish consumption was associated with high-intensity infections. Intervention strategies targeting people with a high frequency of raw fish consumption should be implemented to reduce the probability of severe consequences. |
format |
Article in Journal/Newspaper |
author |
Junling Sun Hualei Xin Zhihua Jiang Menbao Qian Kaixia Duan Yingdan Chen Shizhu Li Wei Li Shiyong Huang Xiaoqin Gan Yichao Yang Zhongjie Li |
author_facet |
Junling Sun Hualei Xin Zhihua Jiang Menbao Qian Kaixia Duan Yingdan Chen Shizhu Li Wei Li Shiyong Huang Xiaoqin Gan Yichao Yang Zhongjie Li |
author_sort |
Junling Sun |
title |
High endemicity of Clonorchis sinensis infection in Binyang County, southern China. |
title_short |
High endemicity of Clonorchis sinensis infection in Binyang County, southern China. |
title_full |
High endemicity of Clonorchis sinensis infection in Binyang County, southern China. |
title_fullStr |
High endemicity of Clonorchis sinensis infection in Binyang County, southern China. |
title_full_unstemmed |
High endemicity of Clonorchis sinensis infection in Binyang County, southern China. |
title_sort |
high endemicity of clonorchis sinensis infection in binyang county, southern china. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2020 |
url |
https://doi.org/10.1371/journal.pntd.0008540 https://doaj.org/article/1dcf3f1a849a40e6bf37615cb09cc2ff |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 14, Iss 8, p e0008540 (2020) |
op_relation |
https://doi.org/10.1371/journal.pntd.0008540 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008540 https://doaj.org/article/1dcf3f1a849a40e6bf37615cb09cc2ff |
op_doi |
https://doi.org/10.1371/journal.pntd.0008540 |
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PLOS Neglected Tropical Diseases |
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14 |
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8 |
container_start_page |
e0008540 |
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1766346598221086720 |