Canine chondrodysplasia caused by a truncating mutation in collagen-binding integrin alpha subunit 10.

• Published in: PLoS ONE
• Main Authors: Kaisa Kyöstilä, Anu K Lappalainen, Hannes Lohi
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2013
• Subjects: Medicine; R; Science; Q; Nes; Nes’; karelian
• Online Access: https://doi.org/10.1371/journal.pone.0075621; https://doaj.org/article/1bfbde2f37a243c19fcc5e9ad56d2a37

The skeletal dysplasias are disorders of the bone and cartilage tissues. Similarly to humans, several dog breeds have been reported to suffer from different types of genetic skeletal disorders. We have studied the molecular genetic background of an autosomal recessive chondrodysplasia that affects t...