Phytochemical analysis and anti-oxidant activities of Albuca bracteata Jacq. and Albuca setosa Jacq bulb extracts used for the management of diabetes in the Eastern Cape, South Africa
Objective: The bulb of Albuca bracteata Jacq., and Albuca setosa commonly used in Eastern Cape Province of South Africa for the treatment of several types of disease conditions including diabetes, was investigated for their phytochemical contents and antioxidant activities. Methods: The antioxidant...
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Wolters Kluwer Medknow Publications
2017
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ftdoajarticles:oai:doaj.org/article:1bc8b54980ad44f493908a1dacdbb899 2023-05-15T15:13:22+02:00 Phytochemical analysis and anti-oxidant activities of Albuca bracteata Jacq. and Albuca setosa Jacq bulb extracts used for the management of diabetes in the Eastern Cape, South Africa Samuel Odeyemi Anthony Afolayan Graeme Bradley 2017-06-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2017.05.013 https://doaj.org/article/1bc8b54980ad44f493908a1dacdbb899 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169116307481 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2017.05.013 https://doaj.org/article/1bc8b54980ad44f493908a1dacdbb899 Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 6, Pp 577-584 (2017) Phytochemicals Antioxidants Ornitogalum longibrateum Albuca bracteata Diabetes Albuca setosa Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2017 ftdoajarticles https://doi.org/10.1016/j.apjtb.2017.05.013 2022-12-31T14:24:52Z Objective: The bulb of Albuca bracteata Jacq., and Albuca setosa commonly used in Eastern Cape Province of South Africa for the treatment of several types of disease conditions including diabetes, was investigated for their phytochemical contents and antioxidant activities. Methods: The antioxidant activity was determined by evaluating the effect of various solvent extracts (acetone, methanol, ethanol and water) on 2,2 – diphenyl-2-picrylhydrazyl (DPPH) scavenging activity, 2,2′ – azino-bis (3-ethylbenzthiazoline-6-sulfonic acid diammonium salt (ABTS), ferric reducing power, hydrogen peroxide and nitric oxide scavenging activity while the various extracts were also analysed for phytochemical their contents. Results: The results obtained indicate that polyphenols, proanthocyanidins, saponins and alkaloids are present in higher concentrations. The composition of phenols (117 mg/g), flavonols (26.28 mg/g), proanthocyanidins (84.85 mg/g) and flavonoids (5.36 mg/g) were significantly higher in the acetone extract while saponin and alkaloids contents were higher in the aqueous extract. Antioxidant studies of the extracts for nitric oxide, hydrogen peroxide, ABTS and DPPH showed high antioxidant potential in a concentration-dependent manner that was not significantly different from Vitamin C, BHT and Rutin used as standard references. The methanol extract showed higher ferric reducing potential compared to the aqueous extract but was significantly different from Vitamin C, BHT and Rutin. Conclusion: This implies that the bulb of Albuca bracteata may serve as a natural source of antioxidants, which together with the numerous phytochemicals present, could account for its folkloric use as a medicinal plant. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 7 6 577 584 |
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Directory of Open Access Journals: DOAJ Articles |
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topic |
Phytochemicals Antioxidants Ornitogalum longibrateum Albuca bracteata Diabetes Albuca setosa Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Phytochemicals Antioxidants Ornitogalum longibrateum Albuca bracteata Diabetes Albuca setosa Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Samuel Odeyemi Anthony Afolayan Graeme Bradley Phytochemical analysis and anti-oxidant activities of Albuca bracteata Jacq. and Albuca setosa Jacq bulb extracts used for the management of diabetes in the Eastern Cape, South Africa |
topic_facet |
Phytochemicals Antioxidants Ornitogalum longibrateum Albuca bracteata Diabetes Albuca setosa Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: The bulb of Albuca bracteata Jacq., and Albuca setosa commonly used in Eastern Cape Province of South Africa for the treatment of several types of disease conditions including diabetes, was investigated for their phytochemical contents and antioxidant activities. Methods: The antioxidant activity was determined by evaluating the effect of various solvent extracts (acetone, methanol, ethanol and water) on 2,2 – diphenyl-2-picrylhydrazyl (DPPH) scavenging activity, 2,2′ – azino-bis (3-ethylbenzthiazoline-6-sulfonic acid diammonium salt (ABTS), ferric reducing power, hydrogen peroxide and nitric oxide scavenging activity while the various extracts were also analysed for phytochemical their contents. Results: The results obtained indicate that polyphenols, proanthocyanidins, saponins and alkaloids are present in higher concentrations. The composition of phenols (117 mg/g), flavonols (26.28 mg/g), proanthocyanidins (84.85 mg/g) and flavonoids (5.36 mg/g) were significantly higher in the acetone extract while saponin and alkaloids contents were higher in the aqueous extract. Antioxidant studies of the extracts for nitric oxide, hydrogen peroxide, ABTS and DPPH showed high antioxidant potential in a concentration-dependent manner that was not significantly different from Vitamin C, BHT and Rutin used as standard references. The methanol extract showed higher ferric reducing potential compared to the aqueous extract but was significantly different from Vitamin C, BHT and Rutin. Conclusion: This implies that the bulb of Albuca bracteata may serve as a natural source of antioxidants, which together with the numerous phytochemicals present, could account for its folkloric use as a medicinal plant. |
format |
Article in Journal/Newspaper |
author |
Samuel Odeyemi Anthony Afolayan Graeme Bradley |
author_facet |
Samuel Odeyemi Anthony Afolayan Graeme Bradley |
author_sort |
Samuel Odeyemi |
title |
Phytochemical analysis and anti-oxidant activities of Albuca bracteata Jacq. and Albuca setosa Jacq bulb extracts used for the management of diabetes in the Eastern Cape, South Africa |
title_short |
Phytochemical analysis and anti-oxidant activities of Albuca bracteata Jacq. and Albuca setosa Jacq bulb extracts used for the management of diabetes in the Eastern Cape, South Africa |
title_full |
Phytochemical analysis and anti-oxidant activities of Albuca bracteata Jacq. and Albuca setosa Jacq bulb extracts used for the management of diabetes in the Eastern Cape, South Africa |
title_fullStr |
Phytochemical analysis and anti-oxidant activities of Albuca bracteata Jacq. and Albuca setosa Jacq bulb extracts used for the management of diabetes in the Eastern Cape, South Africa |
title_full_unstemmed |
Phytochemical analysis and anti-oxidant activities of Albuca bracteata Jacq. and Albuca setosa Jacq bulb extracts used for the management of diabetes in the Eastern Cape, South Africa |
title_sort |
phytochemical analysis and anti-oxidant activities of albuca bracteata jacq. and albuca setosa jacq bulb extracts used for the management of diabetes in the eastern cape, south africa |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2017 |
url |
https://doi.org/10.1016/j.apjtb.2017.05.013 https://doaj.org/article/1bc8b54980ad44f493908a1dacdbb899 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 6, Pp 577-584 (2017) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169116307481 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2017.05.013 https://doaj.org/article/1bc8b54980ad44f493908a1dacdbb899 |
op_doi |
https://doi.org/10.1016/j.apjtb.2017.05.013 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
7 |
container_issue |
6 |
container_start_page |
577 |
op_container_end_page |
584 |
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1766343935656984576 |